|
Name : ureC (BBta_4442) Accession : YP_001240384.1 Strain : Bradyrhizobium sp. BTAi1 Genome accession: NC_009485 Putative virulence/resistance : Virulence Product : urease subunit alpha Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0804 EC number : 3.5.1.5 Position : 4652078 - 4653784 bp Length : 1707 bp Strand : - Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alp DNA sequence : ATGGCCACGCTGACCCGCCGCGCCTATGCCGAGCTCTACGGTCCCACCAAAGGGGATCTCGTCAGGCTCGCCGACACCAG CCTGCTCGCCGAGATCGAGCACGACTACACGACCTACGGCCATGAGCTCCTGGTCGGCGCCGGAAAGAATTTGCGCGACG GCGAGGCCGTCGCGGCGCACCGCACCTCGCAGCACAAGGCCCTCGACGTCGTCGTCAAGAACGCGACCATCGTCGACGCC GTCATCGGCATCGTGAAGGCCGATATCGGCATCCGCGACGGCCGCATCGTCGGCATCGGCAAGGCAGGCAATTCCGACGT GATGCCCGACGTGCATCCGGACATGGTGGTCGGCCACACCACGGCGCCGATCGCCGGCGGTCCGTTCATCGTCACAGCCG GCGCGATCGAGAGCCACGCGCATCTGATCTCGCCGGAACAGTCCGACCACGCGCTGTCCGGCGGCACGACGACGATGATC GGCAACGGCTCGGGGCCGGTGTTCGATGTCGGCTCCGGCTCGGGGCCGAATTTCGGGCATTTCCTCAAGTCGATCGAGTT CTCGCCGCTGAACTACGCGCTGTTCGGCCGTGGCGGCTCCAACCCGGAGGCGGTCGAGGAGGCGGTCGCGGCCGGCGGCA TGTCGGTCAAGATCCATGAGGATTTCGGCGCGGCGCCCGATGTCATCGACAAGACCCTGATCGCCGCTGATCGTCACGAC TTCGCCGTCCACCTGCACACGGACTCGATCAACGAATACGGCTTCTGCGAGGATACGATGGCGGCGGTCGATGGCCGCAC CATCCACATGTATCACGTCGAGGGCGCCGGCGGCGGCCACGCGCCCGATCTGCTCAAGGTGGTCTCATGGCCCAACGTGA TCCCGTCATCGACCAATCCGACCAATCCCTATACCTCCTATGGCATGGAGGAAGGCGTGCCGATGACGATGATCTGTCAT CAGCTCAACTACAATGCACCCGAGGACGTGATGTTCGGTGAGGCGCGGGTGCGCGCGCAGTCGATGGCGGCCGAGGATTT CCTGCACGACATGGGCGCGATCTCGATCTTCGGCACGGATACGCAGGGCATGGGGCGGCTCGCCGAGAACGTCGCCAAAT GCTGGCAGCTCGCCAGCGTCATGAAGGATCGCACCGGCCGGCTGCCGGAGGAGACCACCGCGCGCGCCGACAATGAGCGG ATCAAGCGCTACATCGCCAAGCTCACGATCAACCCGGCGATCGCCGTCGGCATCGATCACGTCGTCGGCTCGATCGAGGT CGGCAAGATGGCCGATCTCGTGCTCTGGCCGCGCGCCTCGTTCGGGCTGAAGCCCTATATGGTGATCAAGAACGGATTCC CGGTGTGGGCGGCGATGGGCGACGGCAATGGCAGCCTCGGCCTGTCGGAGCCGATGATCCAGAAGCGGATGTGGGGCGCG CTCGGCGCCGCACCGCAGCGGCTCGGCGTCAACTTCATGTCCAAGCTCGCGGTCGACGCCGACATCCGTGGCAGGCTCGG GCTGGGACGCGCGACCGTGCAGATCAAGAACGTCCGCCGTTTGCGCAAGACCGACATGATCCGCAACGCGGCGATGCCGC ATGTCGAGGTCGATCCGCAGACCTTCGAGGTGCGCGCCGACGGCAAGCTCCTGATGTGTCCGCCGGCCACGACCGTGCCG CTCGCCAGGAGGTTCATGCTGCGATGA Protein sequence : MATLTRRAYAELYGPTKGDLVRLADTSLLAEIEHDYTTYGHELLVGAGKNLRDGEAVAAHRTSQHKALDVVVKNATIVDA VIGIVKADIGIRDGRIVGIGKAGNSDVMPDVHPDMVVGHTTAPIAGGPFIVTAGAIESHAHLISPEQSDHALSGGTTTMI GNGSGPVFDVGSGSGPNFGHFLKSIEFSPLNYALFGRGGSNPEAVEEAVAAGGMSVKIHEDFGAAPDVIDKTLIAADRHD FAVHLHTDSINEYGFCEDTMAAVDGRTIHMYHVEGAGGGHAPDLLKVVSWPNVIPSSTNPTNPYTSYGMEEGVPMTMICH QLNYNAPEDVMFGEARVRAQSMAAEDFLHDMGAISIFGTDTQGMGRLAENVAKCWQLASVMKDRTGRLPEETTARADNER IKRYIAKLTINPAIAVGIDHVVGSIEVGKMADLVLWPRASFGLKPYMVIKNGFPVWAAMGDGNGSLGLSEPMIQKRMWGA LGAAPQRLGVNFMSKLAVDADIRGRLGLGRATVQIKNVRRLRKTDMIRNAAMPHVEVDPQTFEVRADGKLLMCPPATTVP LARRFMLR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 3e-104 | 48 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 3e-104 | 48 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 5e-100 | 48 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 5e-100 | 48 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 5e-100 | 48 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 5e-100 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ureC | YP_001240384.1 | urease subunit alpha | VFG0270 | Protein | 1e-101 | 47 |
