Gene Information

Name : BBta_3778 (BBta_3778)
Accession : YP_001239761.1
Strain : Bradyrhizobium sp. BTAi1
Genome accession: NC_009485
Putative virulence/resistance : Resistance
Product : tetracycline-efflux transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 3956720 - 3957988 bp
Length : 1269 bp
Strand : +
Note : Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 5 : Inner membrane protein

DNA sequence :
ATGGTCGACACCGAGCTGGCGAGTTCCGACGGCGTACCGTCGCCGCAGGCCCCGCGCCGCGGCGCCGTCGCTTTCATCTT
CGTCACCATCCTGCTCGATATGCTCGCGCTCGGGCTGATCATGCCGATCCTGCCCAAGCTGATCGAGAGCTTCGTCGCCA
ATGACACCGCGCAGGCAGCACGGATCTTCGGCCTGTTCGGCACGGCCTGGGCACTGATGCAGTTCGTGTTCTCGCCGGTG
CTCGGCAGCCTCTCCGACCGGTTCGGCCGGCGGCCGGTCATCCTGCTCTCGAACTTCGGCCTCGCCGCGGACTACGTGCT
GATGGCGATGGCGCCGTCGCTGGCGTGGCTGTTCATTGGCCGGCTGATCTCCGGCATCACCTCGGCCAGCATTTCCACGG
CCTTTGCCTACATCGCCGACCTCACGCCGCCAGAGCGGCGCGCCGCGATCTTCGGCCGCATGGGAGCGGCGTTCGGCGCC
GGCTTCGTGCTCGGCCCGGCGACCGGCGGATTGCTGGGCGATATCGATCCGCGGCTGCCGTTCTGGGCGGCCGCCGGACT
CAGCTTCGTCAATGCGGTCTATGGATTGTTGGTGCTGCCGGAATCGCTGGGGCACGAGCGGCGCAGTCCGTTCCGCTGGC
GGACCGCGAACCCGCTCGGCGCACTGCAATTGCTGCGCTCCGACCGCATGCTGGCCGGGCTGTCCATGGTCAACTTCATC
ACCCAGCTCGCCCATGTCGTGCTGCCGTCGACCTTCGTGCTCTACGCCACCTACCGCTATGGCTGGGATACGCGCACGGT
CGGCCTGACGCTGGCGATCGTCGGCGTGTGCGCCATGGTGGTGCAGGGCGGGGCGGTCGGCTGGATCGTGCGTTCGCTCG
GCGAGCGTGGCGCCTTGCTGCTCGGCCTGTGCAGCGGCACGCTGGGCTTTCTGATCTTTGGCCTCGCGCCGACCGGGATG
CTGAGCTGGCTCGGCATTCCTGCGATGGCGCTCTGGGGCGTCTCCGGCGCGGCGATCCAGGCGCTGATGACACGGCTGGT
GCCGGCGGACCGGCAGGGCCAGCTGCAGGGCGCGACGTCGAGCGTGCAGAGCATGGCCCAGCTCGCCGGGCCGTTCCTGT
TCACGCTGACCTTCGCCTATTTCATCGGAGTCACCGCGCCGGTGCATCTGCCCGGCGCGCCGTTCCTGCTGGCGTCGATG
CTGTTGGTCGTCGCGCTCGCGATCGCGCTGCGGACGATCCGCGCCGCGACAGCCGCAGCCTTATCCTGA

Protein sequence :
MVDTELASSDGVPSPQAPRRGAVAFIFVTILLDMLALGLIMPILPKLIESFVANDTAQAARIFGLFGTAWALMQFVFSPV
LGSLSDRFGRRPVILLSNFGLAADYVLMAMAPSLAWLFIGRLISGITSASISTAFAYIADLTPPERRAAIFGRMGAAFGA
GFVLGPATGGLLGDIDPRLPFWAAAGLSFVNAVYGLLVLPESLGHERRSPFRWRTANPLGALQLLRSDRMLAGLSMVNFI
TQLAHVVLPSTFVLYATYRYGWDTRTVGLTLAIVGVCAMVVQGGAVGWIVRSLGERGALLLGLCSGTLGFLIFGLAPTGM
LSWLGIPAMALWGVSGAAIQALMTRLVPADRQGQLQGATSSVQSMAQLAGPFLFTLTFAYFIGVTAPVHLPGAPFLLASM
LLVVALAIALRTIRAATAAALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 2e-36 43
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 2e-36 43
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 2e-36 43
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 3e-36 43
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 3e-37 42
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 4e-37 42
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 1e-29 41
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 1e-29 41
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 1e-29 41
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 1e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BBta_3778 YP_001239761.1 tetracycline-efflux transporter AY264780.2.gene3.p01 Protein 4e-39 43
BBta_3778 YP_001239761.1 tetracycline-efflux transporter NC_011586.7045189.p0 Protein 2e-33 42
BBta_3778 YP_001239761.1 tetracycline-efflux transporter X75761.gene.p01 Protein 5e-36 42
BBta_3778 YP_001239761.1 tetracycline-efflux transporter AF534183.gene.p01 Protein 2e-37 42
BBta_3778 YP_001239761.1 tetracycline-efflux transporter NC_010410.6002597.p0 Protein 2e-37 42
BBta_3778 YP_001239761.1 tetracycline-efflux transporter CP001485.1.gene2821. Protein 2e-37 42