Gene Information

Name : guaA (BBta_3614)
Accession : YP_001239609.1
Strain : Bradyrhizobium sp. BTAi1
Genome accession: NC_009485
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3783225 - 3784829 bp
Length : 1605 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGCCCAGCCCGACACCCCCGCCAGCGCCGCCACTGAGACCTCCGTGGCCGCGCTCCACGACAAGATCCTGATTGT
CGATTTCGGCAGCCAGGTCACGCAGCTGATCGCGCGCCGGGTGCGCGAGGACGGCGTGTATTGCGAGATCGTGCCGTTCC
AGAAGGCGGAGGCCGCCTTCCGGCAGATGCAGCCCAAGGCCGTGATCCTGTCCGGCGGCCCGGAATCGGTCCACGAGGCC
GGCTCCCCGCGCGCCCCGCAGCTGATCTTCGACTCGGGCGTCCCGGTGATGGGCATCTGCTACGGCCAGATGACGATGGC
CGCCCAGCTCGGCGGCACCGTCGAGGGCGGCCACCACCGCGAGTTCGGCCGCGCCGACGTCGAGGTCAAGACATCGAGCC
GCCTGTTCGATGGCGTCTGGCAACCGGGCGAGCAGCACCAGGTGTGGATGAGCCATGGCGACCGCATCACCCAGATGCCG
CCGGGCTTCTCGGTGGCCGGTGTCTCGCCGAACGCGCCCTTCGCCGTGATCCAGGACGAGACGCGCAAATATTACGGCCT
GATGTTCCACCCCGAAGTGGTGCACACGCCTGATGGCGCCAAGCTGATCCGCAACTTCGTGCGCAACATCGCCGGCCTCG
GCGGCGACTGGACCATGCACGCCTTCCGCGCCGAGGAGATCAAGAAGATCCGCGCCCAGGTCGGCAAGGGCAAGGTGATC
TGTGGCCTCTCCGGCGGCGTCGATTCCGCCGTTGCCGCGGTGCTGATCCACGAGGCGATCGGCGACCAGCTCACCTGCGT
GTTCGTCGATCACGGCCTGCTCAGGCTCAACGAGGCCGAGACCGTCGTCGACCTGTTCCGGCACCACTACAACATTCCGC
TGGTGCATGTGGACGCCTCAAAACTCTTCCTCGGCGAGCTCGCCGGGGTCACCGACCCGGAGCAGAAGCGCAAGACCATC
GGACGACTCTTCATCGACGTGTTCGAGGCCGAGGCCAAGAAGATCGGCGGCGCCGATTTCCTGGCGCAGGGCACGCTCTA
TCCCGACGTGATCGAGAGCGTCTCCTTCACCGGCGGCCCCTCGGTGACGATCAAGTCGCACCACAATGTCGGCGGCCTGC
CGGCGCGCATGAACATGAAGCTGGTCGAGCCGTTGCGCGAATTGTTCAAGGACGAGGTCCGCGTGCTCGGCCGCGAGCTC
GGCCTGCCCGACGTCTTCGTCGGCCGCCACCCGTTCCCGGGCCCGGGCCTCGCCATCCGCTGCCCCGGCGAGATCACGGT
CGACAAGCTCGACATCCTGCGCAAAGCCGACGCCATCTACATCGACGAGATCCGCAAGGCCGGCCTCTACGACACCATCT
GGCAGGCTTTTGCCGTGCTGCTCCCCGTCAAGACCGTCGGCGTCATGGGCGACGGCCGCACCTACGACTACGTCGTCGGC
CTGCGCGCGGTCACGTCAACCGACGGAATGACGGCGGACTTCTATCCGTTCGACATGAAGTTCTTAGGCAACACGGCGAC
GCGCATCATCAACGAGGTGAAGGGCGTGAATAGGGTGGTGTATGATGTGACGAGCAAGCCGCCGGGGACGATTGAGTGGG
AGTAG

Protein sequence :
MTAQPDTPASAATETSVAALHDKILIVDFGSQVTQLIARRVREDGVYCEIVPFQKAEAAFRQMQPKAVILSGGPESVHEA
GSPRAPQLIFDSGVPVMGICYGQMTMAAQLGGTVEGGHHREFGRADVEVKTSSRLFDGVWQPGEQHQVWMSHGDRITQMP
PGFSVAGVSPNAPFAVIQDETRKYYGLMFHPEVVHTPDGAKLIRNFVRNIAGLGGDWTMHAFRAEEIKKIRAQVGKGKVI
CGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRLNEAETVVDLFRHHYNIPLVHVDASKLFLGELAGVTDPEQKRKTI
GRLFIDVFEAEAKKIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPARMNMKLVEPLRELFKDEVRVLGREL
GLPDVFVGRHPFPGPGLAIRCPGEITVDKLDILRKADAIYIDEIRKAGLYDTIWQAFAVLLPVKTVGVMGDGRTYDYVVG
LRAVTSTDGMTADFYPFDMKFLGNTATRIINEVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-132 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-132 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-132 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-118 52