Gene Information

Name : Acry_0643 (Acry_0643)
Accession : YP_001233783.1
Strain : Acidiphilium cryptum JF-5
Genome accession: NC_009484
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 726037 - 726780 bp
Length : 744 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGGAGGCAGACATTCCGGCTCCCATCGTTCTGATCCCGGCACGGCTCGGCTCGACCCGCCTGCCCGGCAAGCCCCTCGC
CGATATCGGCGGAATTCCGATGATTGTCCATGTCCTCCGCCGCGCCGGGGAAGCGGCGATCGGCCCGGTCGCGGTGGCCT
GCGCCGAATCCGCGATCGCCGACGCCGTCCGCGCGGCCGGCGGCACCGCGGTGCTGACCGACCCCGACCTGCCGAGCGGA
TCGGACCGGATCCACGCCGCCCTCGCCACGATCGACCCGGCTTGCGTTCATGACATCGTGGTGAATCTCCAGGGCGATCT
TCCGGGCTTCCCTCCCGAATCGCTGCGCACCCTGATCGCCGTGCTCGACGATCCGGGCTTCGACATCGCCACCCTCGTCG
CCCCCGTCACCACGGCGGAAGAGGCCGCCTCCCCCTCGGTGGTCAAGGCGGCCTGCGGCTTCGGCGAGGGGATCGCCGCC
CCCGCGCTCTATTTCTCGCGCAACCCGATCCCCTCGGGGCCGGGGCCGCTCTGGCACCATGTCGGCGTCTACGCCTATCG
CCGCGCCGCACTCGACCGTTTCGTCGCGGCACCGCCCTCGCCGCTCGAACTGCGCGAAAAGCTCGAACAGCTCCGCGCCC
TCGAACTCGGGATGCGGATCGGCGCGGCGCGGATTGACCGGGCCCCGTTCGGGGTCGATACCCCGGAAGACCTCGACCGC
GCCCGCAGGAACCTTGCCGCATGA

Protein sequence :
MEADIPAPIVLIPARLGSTRLPGKPLADIGGIPMIVHVLRRAGEAAIGPVAVACAESAIADAVRAAGGTAVLTDPDLPSG
SDRIHAALATIDPACVHDIVVNLQGDLPGFPPESLRTLIAVLDDPGFDIATLVAPVTTAEEAASPSVVKAACGFGEGIAA
PALYFSRNPIPSGPGPLWHHVGVYAYRRAALDRFVAAPPSPLELREKLEQLRALELGMRIGAARIDRAPFGVDTPEDLDR
ARRNLAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-30 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-30 41
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-30 41