Gene Information

Name : Gura_3858 (Gura_3858)
Accession : YP_001232581.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4508614 - 4509759 bp
Length : 1146 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes

DNA sequence :
TTGGGAGGTTATATGAAGATTTCGACGCAGGCGGTACAGATTGGTTTGGATTGGGACACGAGGACGGGCGCGGTAACGGT
TCCCATCTATCAGACGGCGACGTTTCGCCACCCCGGGTTGGGGCAGAGCACCGGCTACGACTACAGCCGCTCCGGCAATC
CTACCCGGCAGGCGCTGGAGGATGGGATTGCCCGCCTGGACCGGGGTTGCAGGGGCTTTGCCTACGCATCGGGCATGGCG
GCCATCACCAACCTGCTCCTCCTTTTTCAGCGGGGAGACCACCTGGTCGTTACCGAAGACCTCTACGGCGGCACCTACCG
GCTGTTTGAACAGGTTTTCCAGCAGTACGGCCTGGAATTCACCTACGTGGACACCTCGGACATGGCGGCGGTCAAGGGGG
CGTTCAAGGCCAATACCCGCGGACTGTTTGTCGAATCCCTGACCAATCCGCTGCTGAAGGTGGCCGATATACGGGCACTT
GCCATCCTTTGCAAGGAACGGGGGGCGCTTTGCATCGTCGACAACACCTTTCTCACCCCTTACCTGCTCCGGCCGCTGGA
GTTGGGAGCGGACATCACCGTCTACAGCGCCTCCAAGTACCTGGCCGGTCACAACGACACGGTGGCCGGGCTGGTGGTGG
CGAAGGCGCCGCAACTTGCCGAAAAAATCTACTTCCTGCAGAATTCGGTCGGCGCCGTGCTCGGCCCCCAGGACTCCTGG
CTGGTGATCCGGGGGATGAAGACCCTCGCAATCAGGATGGACCGGCAGGAGGCAAACGCAGGGCGAATAGCCGCATGGCT
GCAGCGCCATCCACTGGTGGCAAAGGTCCATTATCCGGGACTTTCCGATCATCCCGGCCACGCCCTGTTGCAGTCCGAGG
CCGCCGGATTCGGCGCCATGATCGCCTTCGAGGTGAAGGAGCCGGCGCAGGTGGAGCAACTCCTCATGAAGACGCAACTC
ATCTCATTCGCAGAAAGCCTGGGCGGGGTGGAGACGCTCATCACCTTTCCCGAAGCGCAGACCCATGCAGACATCAAGCC
GGAGATCCGCAAAAGGCTTGGGATCAACAACGTGCTCCTGCGCCTCTCGGTGGGGATCGAGGATGCGGACGACCTGATCG
CCGATTTGGAACAGGCGTTTGAATAG

Protein sequence :
MGGYMKISTQAVQIGLDWDTRTGAVTVPIYQTATFRHPGLGQSTGYDYSRSGNPTRQALEDGIARLDRGCRGFAYASGMA
AITNLLLLFQRGDHLVVTEDLYGGTYRLFEQVFQQYGLEFTYVDTSDMAAVKGAFKANTRGLFVESLTNPLLKVADIRAL
AILCKERGALCIVDNTFLTPYLLRPLELGADITVYSASKYLAGHNDTVAGLVVAKAPQLAEKIYFLQNSVGAVLGPQDSW
LVIRGMKTLAIRMDRQEANAGRIAAWLQRHPLVAKVHYPGLSDHPGHALLQSEAAGFGAMIAFEVKEPAQVEQLLMKTQL
ISFAESLGGVETLITFPEAQTHADIKPEIRKRLGINNVLLRLSVGIEDADDLIADLEQAFE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-84 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-86 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-68 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gura_3858 YP_001232581.1 cystathionine gamma-synthase BAC0207 Protein 5e-61 43