Gene Information

Name : Gura_3857 (Gura_3857)
Accession : YP_001232580.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4507343 - 4508479 bp
Length : 1137 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes

DNA sequence :
ATGAAAATCGGCACAAAGATCATCCATAACGGCCATGGCATAGACCCCTACACCAAGGGGCTCTCCATCCCCATTTACCA
GGTTTCCACCTTTGCCCAGGAATCGGTGGACCATTTTGGCAAGTGGGACTACGCCCGCTCCGGCAACCCGACCCGTGAGG
CCCTGGAGGAGACCATTGCCATCCTGGAAAACGGCACCCATGGCTTTGCCTTCGCTTCGGGAATGGCTGCCATCTCCTCG
GCACTCCTGCTCTTTTCTCCCGGCGACCATCTGGTGGTCTGCGAGGACGTCTACGGCGGCGCTTTCAGGGTCCTCACAAC
ACTTTTCAAGCGTCTCGGCATCGAGACGACCTTTGTCGACGCCACTGACCCGGCGAACATCGCCGCAGCCATCCTTCCCG
CCACCAAGGGAATTTACCTGGAGACGCCGTCAAATCCCCTGCTGAAGGTCACCGACATGGCCGCGGCAGTGGCACTGGCC
AAATCGAGGGGGCTTCTGACCCTGGTGGACAACACCTTCATGACCCCCTATCTGCAAAGGCCGCTGGAGCTTGGGTGCGA
CATCGTCCTGCACAGCGGCACCAAGTTTCTGAACGGCCACAGCGACGTGATCTGCGGCTTTGCCGTGGTGCGCGACGAGG
CGCTGGCAAAGCGGATCGGGTTCGTCCAGAACGCATTCGGCGCGGTGCTTGGGCCGCAGGATTCGTGGCTGGTGCTGCGC
GGGTTGAAGACTTTGCGGGTGCGGCTGGAGGAGAGCCAGAAGAGCGCCAGGGCGGTTGCCGAGTGGCTTTCCGAACAAAA
GCGGGTAACGGAGGTATTCTACCCGGGCCTGCCAAGCCATCCCGGCTATGCCGTCCACAACAGCCAGGCAGCGGGGCCGG
GCGCGGTTCTCTCCTTCAAGCTGGAAACGGTGGAACTGACGCGGCGGGTACTGGAAACGGTCGAATTGGCTGCCTTTGCC
GTCAGTCTCGGCGGAGTGGAGAGCATCATCTCCTACCCGGCAAAGATGTCCCATGCGGCCATGCCGCCGGAGGAGCGGGC
AGCGCGCGGGGTGACCGACAATCTGGTGCGCCTGTCGGTGGGGCTGGAGGAGTGTGAGGACCTCATTGCCGATCTGGACC
GGGTGATAAACGGCTAG

Protein sequence :
MKIGTKIIHNGHGIDPYTKGLSIPIYQVSTFAQESVDHFGKWDYARSGNPTREALEETIAILENGTHGFAFASGMAAISS
ALLLFSPGDHLVVCEDVYGGAFRVLTTLFKRLGIETTFVDATDPANIAAAILPATKGIYLETPSNPLLKVTDMAAAVALA
KSRGLLTLVDNTFMTPYLQRPLELGCDIVLHSGTKFLNGHSDVICGFAVVRDEALAKRIGFVQNAFGAVLGPQDSWLVLR
GLKTLRVRLEESQKSARAVAEWLSEQKRVTEVFYPGLPSHPGYAVHNSQAAGPGAVLSFKLETVELTRRVLETVELAAFA
VSLGGVESIISYPAKMSHAAMPPEERAARGVTDNLVRLSVGLEECEDLIADLDRVING

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-92 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-93 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-75 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gura_3857 YP_001232580.1 cystathionine gamma-synthase BAC0207 Protein 1e-61 41