Gene Information

Name : hemC (Gura_0359)
Accession : YP_001229148.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 419732 - 420688 bp
Length : 957 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGCACTGAAAACTCTACGCATAGGAACACGCGCCAGCCAGCTGGCGCTCTGGCAGGCCAACTGGGTGAAGTCTGAGCT
GGAAAAGCGTTATCCGGGGCTGGAAGTATCCCTGCTCAAGATCAAGACCATCGGCGACAAGATCCTCGACGTGCCACTGG
CCCAGGTGGGGGGGAAAGGGCTGTTCGTCAAGGAGATCGAAGAGGCCATGCTGCGCGGCGACATCGACATTGCAGTCCAC
AGCATGAAGGATGTGCCGACCGAGTTTCCCGAAGGTCTGGGACTGCACTGCATTACCGAGCGGGAAGACCCGCGCGATGC
GGTCATTTCCCGTGGCATAAAATTCGCCGACCTGCCAAAAGGGGCGAAAATCGGCACCAGCGCCCTGCGCCGCCAAGCCC
AGCTGCTGAAAATCCGCCCGGACATGGAGATGGTCATCATCCGCGGCAACGTGGAAACCCGCATCAACAAGCTGGAGGCG
GAGAACCTCGACGCCGTAATCCTTGCCGCTGCCGGCCTGAAGCGACTCGGCTTCACCGACAAGGTGGCGGAGTACCTCCC
CACGGATCTTTCCATTCCGGCCATCGGCCAGGGGGCGCTCGGCATCGAATGCCGCCTCGACAACGAAGAGGTGAAAAGCG
CCATCGACTTCTTCAACCATCCCGCCACCGCTTATGCGGTCAGGGCCGAGCGCGCCCTTCTCTGGCGCTGCGAAGGGGGC
TGCCAGGTCCCCATTGCCGCATTCGGCGAGGTTGAAGGCGACCAGCTGAAGCTGACCGGCTTCATCGCTTCGGTGGACGG
CAAAACCTCGGTGAAGGGGAGCGTCAGCGGACCTGCTGAAGAGTGCGAAAAACTCGGCATCACCCTTGCCGAGCAACTGC
TCAAGGACGGTGGTCACGAGATCCTTGCCGAAGTCTACCAGCGGGAAGTTTCACGGGAAAAAGAGATTCCCGTTTAA

Protein sequence :
MALKTLRIGTRASQLALWQANWVKSELEKRYPGLEVSLLKIKTIGDKILDVPLAQVGGKGLFVKEIEEAMLRGDIDIAVH
SMKDVPTEFPEGLGLHCITEREDPRDAVISRGIKFADLPKGAKIGTSALRRQAQLLKIRPDMEMVIIRGNVETRINKLEA
ENLDAVILAAAGLKRLGFTDKVAEYLPTDLSIPAIGQGALGIECRLDNEEVKSAIDFFNHPATAYAVRAERALLWRCEGG
CQVPIAAFGEVEGDQLKLTGFIASVDGKTSVKGSVSGPAEECEKLGITLAEQLLKDGGHEILAEVYQREVSREKEIPV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-71 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-71 52