Gene Information

Name : leuS (Gura_3134)
Accession : YP_001231868.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3702407 - 3704881 bp
Length : 2475 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGAAGAAAAGTATCTCCCGAGCAGGGTTGAGGAGAAATGGCAGAAATTCTGGGAAGCCAATAAGAGCTTCAGGGCAAC
CGAGGATAAGACGAGGGAAAAGTATTATCTTCTGGAAATGTTTCCCTATCCTTCGGGGCGCATTCACATGGGGCATGTGC
GCAACTACTCGATCGGCGACGTGATAGCCCGGTTCAAAAGGATGAAAGGCTTTAATGTCCTTCATCCCATGGGGTGGGAT
GCCTTCGGCATGCCGGCAGAGAACGCGGCGATCCAGAACAAGAGCCACCCTGCCAAATGGACCTATGAAAACATCGCTTA
TATGCGGGGCCAATTGAAAAAAATGGGCCTTTCCTATGATTGGGATCGGGAACTTGCGACCTGCGACGTGGACTACTACA
AATGGGAGCAGTTGATTTTCCTGCAGATGTATAAAAAGGGTCTTGCCTATAAAAAGATATCTTCCGTTAACTGGTGCCCC
AAATGTGAAACTGTTCTGGCCAATGAACAGGTTGAAGACGGCTGCTGTTGGCGGTGCGACAGTAATGTGGATCAGAAGGA
ACTTGAGCAGTGGTCATTCAGGATAACCGACTATGCAGAGGAACTCCTGGAATACACCTACAAGCTCCCCGGTTGGCCGG
AGCGTGTCCTGACCATGCAGCGCAACTGGATAGGGCGAAGCACCGGTTGCGAAATAGATTTCCCCATCGAAGGGCAAATG
GACAAGATAAAGGTTTTTACCACCCGTCAGGATACCCTGTTCGGCGCCACATTCATGTCTCTGGCGCCGGAACATCCCAT
GGCACTGGAGTTGACTACCCCTGAAAACATGGCAACTGTAGCGGCTTTTATCGAGAAGGTCAAGAAGACCGATCGTATCC
GGCGCACTGCAGAAGACTTTGAAAAGGAAGGGGTGTTTACCGGTTCGTACTGCATAAATCCGGTCACTAACCGACGGATG
CCGGTCTATCTCGCCAATTTTGTCCTGACCGACTACGGCACCGGGGCGGTTATGGCGGTACCGACCCATGACCAGCGCGA
TTTCGAGTTCGCGCGGAAATACGATATCCCCATGGGTGTGGTGATCCAGCCGGAAGGGGAGGCATTGGACCCGCAGACGA
TGGCGGAAGCTTTCACTGCTGAAGGGATCATGGTCAACTCCGGCAGGTTTGACGGCCTGAAAAGCGGCGCGGCCAAAGAG
CAGATTGCCGATTATCTGGAGAAGGAGGGCATCGGCAAGAAGACGGTCAATTACCGTCTGCGTGACTGGGGGATTTCACG
GCAACGCTACTGGGGGAACCCTATTCCCATGATTTACTGCGACCTTTGCGGAGCGGTGCCCGTGCCCGAAACGGATCTGC
CGGTGGTTCTTCCCATGGACGCCACGTTTACCGGTGAGGGGGGTAATCCACTGGATAAGGTGGATTCCTTCGTCAATACG
ACCTGTCCCCAGTGTGGCGAAGCCGCCCGCAGGGAGACCGACACCATGGACACCTTTGTGGAATCCTCATGGTATTTCCT
CCGTTACTGCTGCCCCGACTTTGTTTCCGGGCCGCTGGACAAGGAGAAGACCGAATACTGGATGTCGGTGGACCAGTATA
TCGGCGGAATCGAGCATGCGGTCATGCACCTGCTCTATGCGCGCTTCTTCACCAAGGTATTGCGCGATCTGGGCTATTGC
GACATCGACGAGCCGTTCACCAACCTTCTCACCCAGGGGATGGTGATCAAGGATGGGGCGAAGATGAGCAAGTCGAAGGG
GAATGTGGTCGACCCCAACGCCCTTATCGATAAATACGGTGCTGACACGGCCCGACTCTTCTCTCTCTTTGCTGCGCCGC
CGGAAAAGGACCTGGACTGGAGCGATCAGGGGGTTGACGGCAGTTTCCGTTTTCTCAACCGTGTATGGAAACTGGTCTAC
GATACCCTGCCCATCATCGGCGGTGCGGGAGCTCTCGATCCTGCCGGGTTGACCAACGAAGGGAAGGGGTTGCGCCGCCA
GGTGCACAAGACCATCAGGAAGGTGACGGAAGATATCGAGGAACGGTTCCACTTCAACACGGCCATAGCTGCCACAATGG
AACTGGTCAATACCATCCAGTCGTTTGAGCCGAAAAACAGTCCGCAAAATGCACCGGTGCTCAAGGAGGCAATCGAATCG
GTAGTGATGCTGCTTGCCCCCTTTGTTCCCCATTTCACCGAAGAGCTGTGGGCCCAGCTCGGTAACAATAAAAGCCTGGA
GCAGGCAGGCTGGCCGGCATTTGATTCAGCTGCGGCAATTGATGAAGAGCTGCTGGTCGTTGTTCAGGTTAATGGCAAGC
TGCGCGGGAAGCTGACCGTTGCCGTTACCGCTTCGGAAGATGACGTAAAAGGCGCCGCCCTTGCCGACGAGCGGGTGAAG
CCGTTTATTGAAGGGAAGAGTGTAAAGAAGATTGTCTATGTTCCCGGCAAGCTGGTTAACATCGTTGTAGGTTAA

Protein sequence :
MEEKYLPSRVEEKWQKFWEANKSFRATEDKTREKYYLLEMFPYPSGRIHMGHVRNYSIGDVIARFKRMKGFNVLHPMGWD
AFGMPAENAAIQNKSHPAKWTYENIAYMRGQLKKMGLSYDWDRELATCDVDYYKWEQLIFLQMYKKGLAYKKISSVNWCP
KCETVLANEQVEDGCCWRCDSNVDQKELEQWSFRITDYAEELLEYTYKLPGWPERVLTMQRNWIGRSTGCEIDFPIEGQM
DKIKVFTTRQDTLFGATFMSLAPEHPMALELTTPENMATVAAFIEKVKKTDRIRRTAEDFEKEGVFTGSYCINPVTNRRM
PVYLANFVLTDYGTGAVMAVPTHDQRDFEFARKYDIPMGVVIQPEGEALDPQTMAEAFTAEGIMVNSGRFDGLKSGAAKE
QIADYLEKEGIGKKTVNYRLRDWGISRQRYWGNPIPMIYCDLCGAVPVPETDLPVVLPMDATFTGEGGNPLDKVDSFVNT
TCPQCGEAARRETDTMDTFVESSWYFLRYCCPDFVSGPLDKEKTEYWMSVDQYIGGIEHAVMHLLYARFFTKVLRDLGYC
DIDEPFTNLLTQGMVIKDGAKMSKSKGNVVDPNALIDKYGADTARLFSLFAAPPEKDLDWSDQGVDGSFRFLNRVWKLVY
DTLPIIGGAGALDPAGLTNEGKGLRRQVHKTIRKVTEDIEERFHFNTAIAATMELVNTIQSFEPKNSPQNAPVLKEAIES
VVMLLAPFVPHFTEELWAQLGNNKSLEQAGWPAFDSAAAIDEELLVVVQVNGKLRGKLTVAVTASEDDVKGAALADERVK
PFIEGKSVKKIVYVPGKLVNIVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-160 42