Gene Information

Name : guaA (Gura_3123)
Accession : YP_001231857.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3689900 - 3691450 bp
Length : 1551 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTACCGACATACACTCCGAAAAAATTCTCATCCTTGATTTCGGCTCCCAGGTGACCCAGTTGATTGCCCGGCGGGT
CAGGGAGCAGAGCATATACTGCGAAATTCATCCTTACTCCATGAGTTTTGAGAAAATCAAGGAGTTCGCCCCGAAGGGGA
TCATTCTTTCCGGCGGTCCTTCCAGCGTTTACGATAAGGATGCGCCCCACTCCGATCTCGGTGTGTTTGACCTGGGGCTT
CCCGTGCTGGGCATCTGCTACGGCATGCAGCTGATGACCCAGCAGCTCGGGGGAAAGGTTGAGCGCTCGGACAAGCGCGA
ATTCGGCGGTTCTTCCTTGCAGCTTGACGATGTGAGCGACCTGTTCGCTGGTTTCGACGGAGCTGCGGATGTCTGGATGT
CCCACGGCGACCGGATCGAGGAGATGCCGGCCGGTTTCCAGGTGATCGCCCATACCGAGCATTGCCCTGTTGCGGCAATG
AAGGACGAGAAGCGGCATTTCTACGGCGTCCAGTTCCACCCGGAGGTGGTGCACACCCCGCGCGGCGACGAGATGTTCGG
CAACTTCCTCTTCAATATCTGCGGTTGTGAACCCACCTGGACCATGGCCAACTTCATCGAAACAGAGATCGAGTCCATCC
GCCGCAAGGTGGGGACCGGCAGGGTTCTCTGCGCACTTTCCGGCGGCGTCGATTCTTCGGTCGTGGCGGTCCTCATTCAC
AAGGCGATAGGCGACCAGCTCCATTGCGTCTTTGTCAACAACGGCCTGCTCCGCAAAGGTGAAGCAGAGAAAGTCGTCAA
CCTGTTCAGCAAGCATTTCCGCATCAACCTCGATTATGTGGACGCCAGCGATCGTTTCCTGGAAAAACTGAGCGGCGTTT
CCGATCCGGAAACAAAACGGAAGATCATCGGCAATGAGTTCATTTACCTGTTCGAGGAAGAGGCGAAAAAGATCGGCAAG
GTCGACTACCTGGCCCAAGGGACTCTCTATCCCGACGTCATCGAATCGGTCTCCACCAAGGGGCCGTCAGCGGTCATCAA
GAGCCATCACAACGTGGGCGGTCTGCCGGAGAAGATGAATCTGAAACTCCTGGAGCCGGTCCGCGAACTGTTCAAAGACG
AAGTTCGCCTCCTGGGGAAGGAACTGGGGATGCCGGACGAGGTCATCTACCGTCAGCCGTTTCCAGGCCCGGGGTTGGCT
ATTCGCTGTATCGGCGAACTTTCCAGGGAGAATCTCGATATCCTGCGCGAGGCGGATGCCATCGTTATCGACGAGATCAG
AAAAGCAGGGCTCTACCGGGAAATCTGGCAATCCTTTGCCGTGCTGTTGCCGGTGAAGACCGTCGGCGTCATGGGAGATG
CCCGAACCTACGAAAACACCGTGGCCCTGAGGGCGGTCAATTCCCTTGACGGCATGACCGCCGACTGGGTAAAATTGCCT
TACGAGTTGTTGGGAAGCATTTCTTCGCGGATCATCAACGAGGTCAAAGGGGTCAACCGGGTCGTCTACGATATCAGCCA
GAAACCGCCCGCGACCATAGAATGGGAATAG

Protein sequence :
MTTDIHSEKILILDFGSQVTQLIARRVREQSIYCEIHPYSMSFEKIKEFAPKGIILSGGPSSVYDKDAPHSDLGVFDLGL
PVLGICYGMQLMTQQLGGKVERSDKREFGGSSLQLDDVSDLFAGFDGAADVWMSHGDRIEEMPAGFQVIAHTEHCPVAAM
KDEKRHFYGVQFHPEVVHTPRGDEMFGNFLFNICGCEPTWTMANFIETEIESIRRKVGTGRVLCALSGGVDSSVVAVLIH
KAIGDQLHCVFVNNGLLRKGEAEKVVNLFSKHFRINLDYVDASDRFLEKLSGVSDPETKRKIIGNEFIYLFEEEAKKIGK
VDYLAQGTLYPDVIESVSTKGPSAVIKSHHNVGGLPEKMNLKLLEPVRELFKDEVRLLGKELGMPDEVIYRQPFPGPGLA
IRCIGELSRENLDILREADAIVIDEIRKAGLYREIWQSFAVLLPVKTVGVMGDARTYENTVALRAVNSLDGMTADWVKLP
YELLGSISSRIINEVKGVNRVVYDISQKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-153 59
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-153 59
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-153 59
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-130 53