Gene Information

Name : Gura_2980 (Gura_2980)
Accession : YP_001231725.1
Strain : Geobacter uraniireducens Rf4
Genome accession: NC_009483
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3443168 - 3443923 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAAAATAACAGCAATTATTCCCGCAAGATATGCATCCACCCGTTTTGAAGGGAAAGCCCTTGCCGACATCATGGGCAA
GCCCATGGTGCAACATGTCTACGAGCGGACCGCCAAAGCCTCGCTGGTTTCCGAAGTAATCGTGGCCACTGACGACGAGC
GGATTGCCGCAGCTGTCCATGCATTCGGCGGCAGGGCCGAGATGACCTCAAGGGTGCATGAAACCGGGACGGACAGGCTG
GCCGAAGTGGCGGCGCGTCTCGATTCCGACATCATCGTCAATGTTCAGGGCGACGAGCCCCTCATTGAGCCTGCCATGAT
CGATGAGGCGATCAAACCGCTCGCCGAGGATTCTTCTGTCATGATGGGGACCCTCAAAACACGCATCAAGACCTTGCACG
ATTTTCTCAGCCCCAATGTGGTCAAGGTGGTTACCGACTGGGAAGGGTATGCCCTTTATTTTTCCCGTTCACCGCTACCC
AATTTCCGCGACAAGTGGAATGATCTGAAGGACGAGGCGTTTGCCTCGCGTAAACTGCTCTGCTACAAGCACGTGGGACT
GTATGTTTACCGTCGCGACTTCCTCCTCCAATTCGCCCAGATGTCACCCACTTACCTGGAAATGGCGGAAAAGCTGGAGC
AGCTCCGGGTTCTGGAAAACGGTTATAGAATCAAGGTCGTGGAGACCGATTATGAATCCATAGGGGTCGATACTCCCGGC
GACCTGGAGAAGGTGTTGGAGAGACTTAAAAAGTAG

Protein sequence : 
MKITAIIPARYASTRFEGKALADIMGKPMVQHVYERTAKASLVSEVIVATDDERIAAAVHAFGGRAEMTSRVHETGTDRL
AEVAARLDSDIIVNVQGDEPLIEPAMIDEAIKPLAEDSSVMMGTLKTRIKTLHDFLSPNVVKVVTDWEGYALYFSRSPLP
NFRDKWNDLKDEAFASRKLLCYKHVGLYVYRRDFLLQFAQMSPTYLEMAEKLEQLRVLENGYRIKVVETDYESIGVDTPG
DLEKVLERLKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-43 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-42 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-43 46