Gene Information

Name : guaA (SynRCC307_0049)
Accession : YP_001226305.1
Strain : Synechococcus sp. RCC307
Genome accession: NC_009482
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 45105 - 46796 bp
Length : 1692 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGATCGCTCCCGTCAGTTGTGGGCGGTTGGACCGCGGGGTCAGTCCTGGTTCGCTGAGGCTGCGTTTTAGGCTCTTTCG
ATTGCCTTACGTGCCGATGTCCGCTGCTCTAGCTGGCCTGGAGGGAGCAGATGGGCGCCGCCCAGCGATCGTCATCCTTG
ATTTTGGCTCGCAGTACTCCGAGCTGATTGCCAGGCGTGTACGGGAGACCGAGGTCTATTCCTTGGTGGTCAGCCACACC
ACCACCCTCGAGCAGTTGAAGGCCCTGGGACCGCGCGGAATCATCCTCAGCGGCGGGCCCAGCTCGGTGTATGCCGCTGG
AGCTCCGTTGTGCGATCCAGGCATCTGGGATCTGGGGATCCCGGTTCTGGGGGTTTGCTACGGCATGCAGCTGATGGTGC
AGCAGCTGGGCGGTTCCGTTGAAGCATCAGAACGGGGTGAATACGGCAAGGCTCCGCTGTTTGTTGACGATCCCACCGAT
CTGCTCACCAACGTCGACGACGGTTCGACGATGTGGATGAGCCACGGGGATTCGGTGCAAGCCCTCCCCGATGGCTTCAC
GCGCCTGGCCCACACCGACAACACCCCAGAAGCGGCGATTGCCCACCACGGCCGCAAGCTCTACGGCGTTCAGTTCCATC
CGGAGGTGGTGCACTCCACCTGCGGCATGGCCCTGATCCGCAATTTCATCTACCACGTGTGTGGTTGTGAGCCGGATTGG
ACCACTGAAGCCTTCATTGATGAGGCGATTGCCGATGTGCGCGCCCGGGTGGGGAGCAAACGCGTGCTGCTGGCCCTCTC
CGGTGGCGTGGACTCCTCAACCTTGGCCTTTTTGCTGCATAAGGCCATCGGTGATCAGCTCACCTGCATGTTCATCGACC
AGGGCTTCATGCGCAAAGGCGAGCCCGAGTTTTTGGTCGAGTTTTTCGATAAGCGCTTCCACATCAATGTGGAGTACATC
AATGCCCGGGAGCGCTTCATCAACAAGCTCGCTGGCATTACCGATCCCGAGGAAAAGCGCCGCATCATCGGCACCGAATT
CATTCGGGTGTTTGAAGAGGAGAGCAAGCGGCTTGGACCTTTTGATTACCTCGCCCAGGGCACGCTCTATCCCGATGTGA
TTGAGAGCGCTGGCACCAACGTCGACCCCAAAACCGGCGAGCGCGTGGCGGTGAAGATCAAGAGCCACCACAACGTGGGT
GGTTTGCCTAAGGACCTTCAGTTCAAGTTGGTGGAGCCCCTGCGCCGTCTGTTTAAAGACGAGGTGCGCAAAGTGGGCCG
CAGCCTTGGCTTGCCAGAGGAGATTGTCCGGCGTCACCCCTTCCCTGGGCCGGGCTTAGCGATCAGGATTCTTGGCGAAG
TCAGCGAAGAGAAGCTCGACATCTTGCGCGATGCCGATCTGATCGTGCGTGAAGAGGTGCGCGATGCCGGCCTCTATCAC
GACATTTGGCAGGCCTTTGCGGTGCTGTTGCCCGTGCGCAGCGTTGGTGTGATGGGCGATAAGCGCACCTACGCCTACCC
AATCGTGTTGCGTTGCGTGGGCAGTGAAGACGGCATGACCGCGGATTGGTCGCGCTTGCCCTACGACTTGATGGAGCGCA
TCTCCAATCGAATCGTCAATGAGGTGAATGGGGTTAACCGCGTCGTCTATGACATCACCAGCAAGCCGCCCGGAACCATC
GAGTGGGAGTGA

Protein sequence :
MIAPVSCGRLDRGVSPGSLRLRFRLFRLPYVPMSAALAGLEGADGRRPAIVILDFGSQYSELIARRVRETEVYSLVVSHT
TTLEQLKALGPRGIILSGGPSSVYAAGAPLCDPGIWDLGIPVLGVCYGMQLMVQQLGGSVEASERGEYGKAPLFVDDPTD
LLTNVDDGSTMWMSHGDSVQALPDGFTRLAHTDNTPEAAIAHHGRKLYGVQFHPEVVHSTCGMALIRNFIYHVCGCEPDW
TTEAFIDEAIADVRARVGSKRVLLALSGGVDSSTLAFLLHKAIGDQLTCMFIDQGFMRKGEPEFLVEFFDKRFHINVEYI
NARERFINKLAGITDPEEKRRIIGTEFIRVFEEESKRLGPFDYLAQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVG
GLPKDLQFKLVEPLRRLFKDEVRKVGRSLGLPEEIVRRHPFPGPGLAIRILGEVSEEKLDILRDADLIVREEVRDAGLYH
DIWQAFAVLLPVRSVGVMGDKRTYAYPIVLRCVGSEDGMTADWSRLPYDLMERISNRIVNEVNGVNRVVYDITSKPPGTI
EWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-145 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-144 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-145 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-135 54