Gene Information

Name : lysS (SynRCC307_0114)
Accession : YP_001226370.1
Strain : Synechococcus sp. RCC307
Genome accession: NC_009482
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 110673 - 112181 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGAGCGAGCTGCGAGATACCCGCCTGGAGAAAGCCCAGGCATTAATTGAATGCGGCCAAGTGCCGTATGCCCTGCGTTT
TGAGCCAAGCCATCGCACCGCTGAGCTGCAGCAAGCTCACGCCGATCTGCCCAATGGCGAAGAGCGTGATGTCTCCGTTG
CGATCGCTGGCCGCGTGATGACGCGCCGGGTCATGGGCAAGTTGGCGTTTTTCACCCTCGCTGATGAGACCGGCCCCATT
CAGCTGTTTTTGGAAAAAGCCGCGCTGGGAGATGCGTTTAAGCAGATCACCAGCCTGGTGGATGCCGGCGACTGGATCGG
GGTCAAGGGCACCTTGCGCCGCACCGATCGCGGTGAGTTGTCGGTGAAGGCAGCGCAATGGCAGATGCTCAGCAAAAGCC
TGCAGCCGCTACCGGACAAATGGCATGGCCTGGCTGATGTGGAGAAGCGCTACCGCCAGCGCTACCTCGATCTGATCGTT
TCTCCCGATACCCGCGACACCTTCCGCCGCCGCGCGCAGCTGGTGAGCGGCATCCGCCGCTGGCTGGATGAGCGCGATTT
CCTGGAGATTGAAACCCCTGTGCTGCAAAGCGAGCCCGGAGGCGCCGATGCCCGGCCCTTTGAAACGCACCACAACGCCC
TGGATCTGCCGTTAACGCTGCGCATTGCGACCGAGCTCCACCTCAAGCGCTTGGTGGTGGGTGGTTTTGAGCGGGTCTAT
GAGCTGGGCCGGATTTTCAGAAATGAGGGCGTCAGCACGCGCCACAACCCTGAATTCACCTCAGTGGAGATCTATCAAGC
CTTCGCTGATTACAACGACATGATGGATCTCACCGAGGAGCTGATCAGCTCGGTGACCCAGCAGGTTTGCGGCAGCACCT
TGATCAACTACCAAGGCACCGAGATCAATTTGGCCCCGGGCTGGCGCCGGGCCACCATGCATGAACTGGTGAAAGAAGCG
ACTGGGCTTGATTTCGCCGGCTTCAGTAGCCGCGAAGATGCTGCCGCAGCCATGGAAGCCAAGGGGTTGCAGACCCCGGC
CTTGGCGGATTCGGTGGGCCGTTTGCTCAATGAGGCCTTTGAGCAGGCCGTGGAAGAAACCCTGATTCAGCCCACCTTCG
TTACTGACTATCCCGTTGAGATTTCACCGTTGGCGCGGTCCCACCGCAGCAAGCCAGGGTTGGTGGAGCGTTTTGAGCTG
TTCATCGTCGGCCGTGAGCATGGCAATGCCTTCAGTGAGCTGACTGATCCAGTGGATCAGCGTCAACGCCTCGAGGCGCA
GCAAGAGCGGCGTGCAGCAGGTGATCTAGAGGCGCAGCGCGTTGATGAGGACTTTTTGAATGCCCTTGAGGTGGGCATGC
CACCCACCGGTGGTTTGGGCATTGGCATTGATCGCCTGGTGATGCTGCTCACCGATAGCCCATCGATCCGTGATGTGATC
GCGTTTCCGCTGCTAAAGCCGGAAAGCCGAGACGGGTCCGCCGCAGTGGATAATGGTTCCACTGAGTAG

Protein sequence :
MSELRDTRLEKAQALIECGQVPYALRFEPSHRTAELQQAHADLPNGEERDVSVAIAGRVMTRRVMGKLAFFTLADETGPI
QLFLEKAALGDAFKQITSLVDAGDWIGVKGTLRRTDRGELSVKAAQWQMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIV
SPDTRDTFRRRAQLVSGIRRWLDERDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGFERVY
ELGRIFRNEGVSTRHNPEFTSVEIYQAFADYNDMMDLTEELISSVTQQVCGSTLINYQGTEINLAPGWRRATMHELVKEA
TGLDFAGFSSREDAAAAMEAKGLQTPALADSVGRLLNEAFEQAVEETLIQPTFVTDYPVEISPLARSHRSKPGLVERFEL
FIVGREHGNAFSELTDPVDQRQRLEAQQERRAAGDLEAQRVDEDFLNALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
AFPLLKPESRDGSAAVDNGSTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-106 49
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 9e-82 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001226370.1 lysyl-tRNA synthetase VFG1668 Protein 1e-106 49