Gene Information

Name : lysS (SynWH7803_0177)
Accession : YP_001223900.1
Strain : Synechococcus sp. WH 7803
Genome accession: NC_009481
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 194732 - 196201 bp
Length : 1470 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGTCCGATCTGCGTGAGACCCGCCTCGAGAAGGTGTCAGCCCTGCGCGACCAGGGCCGGGAGCCCTACGCCCTCACCTT
TGACCCCAGCGACCGGATGGCTCGGTTGCAGAGCGACCATGCCGATCTGCCCAAGGGTGAGGAGCGGGATTGTGCGGTGG
CTGTGGCCGGGCGGGTGATGACCCGGCGGGTGATGGGCAAGCTTGCGTTCTTCACCCTGGCCGATGAAACCGGCACGATC
CAGCTGTTTCTGGAGAAGGCGGCACTCGGCGAGGCCTTCGCTCAGATTACGTCTCTGGTCGATGCCGGTGATCTGATCGG
CGTGCGTGGCACGTTGCGCCGCACCGACCGGGGGGAGTTGTCGGTGAAAGTGGCGGAGTGGACCATGCTCACCAAGTCTC
TGCAGCCCCTGCCGGACAAGTGGCACGGGCTGGCGGACGTGGAGAAGCGCTATCGCCAGCGCTATCTCGATCTGATCGTG
ACCCCGCAGTCGCGCGAGACGTTCCGACGCCGGGCGCTGACCGTGAGTGCGATCCGTCGCTGGCTCGATGAGCGCGAGTT
CCTCGAGATTGAAACGCCCGTGCTGCAGTCGGAGGCAGGAGGAGCCGATGCGCGTCCGTTCATCACCCACCACAACACGT
TGGATCTCCCGCTCTACCTGCGCATCGCCACCGAATTGCACCTCAAACGCTTGGTGGTGGGCGGTTTTGAGCGGGTCTAC
GAGCTGGGTCGCATCTTCCGCAACGAGGGGGTGAGCACCCGCCACAACCCTGAGTTCACCTCGGTGGAGGTGTATCAGGC
CTATGCCGATTACCTGGGGATGATCGAGCTCACCGAGTCGATGATCGCCTCGGTGTGCGAGCAGGTGTGCGGCGGCACGC
GGCTCACCTACCAAGGCACGGAGATCGATCTCACCCCGCCCTGGCGCCGGGCGACGATGCACGAGCTGGTGGAGGAAGCC
ACCGGCCTCGACTTCACGGCTTTCGCGGATCGGGCGGCGGCCGCTGAAGCGATGACGGCCAAGGGGTTGCCGGTGCCAGA
CAAAGCCGATTCGGTGGGCCGTCTGCTCAATGAGGCTTTTGAGCATGCCGTGGAAGCCAATCTGATCCAGCCCACCTTCG
TGCTCGACTATCCCGAGGAGATCTCTCCGCTCGCCCGCAAGCACCGCAGCAAGCCTGGCTTGGTGGAGCGCTTCGAGTTG
TTCATCGTTGGTCGGGAAACGGCCAATGCCTTCAGCGAGTTGATCGATCCAGTGGACCAGCGCGGGCGCCTAGAGGCTCA
GCAGGCACGCCGGGCCGCCGGTGATGAGGAAGCCCAGGGGGTGGATGAGGACTTTCTGCAGGCCCTGGAAGTGGGCATGC
CCCCCACTGGAGGCCTGGGCATCGGCATCGACCGCCTGGTGATGCTGCTCACGGACAGTCCCTCCATCCGCGATGTGATC
GCCTTCCCGCTGCTGCGTCCTGAGGGCTGA

Protein sequence :
MSDLRETRLEKVSALRDQGREPYALTFDPSDRMARLQSDHADLPKGEERDCAVAVAGRVMTRRVMGKLAFFTLADETGTI
QLFLEKAALGEAFAQITSLVDAGDLIGVRGTLRRTDRGELSVKVAEWTMLTKSLQPLPDKWHGLADVEKRYRQRYLDLIV
TPQSRETFRRRALTVSAIRRWLDEREFLEIETPVLQSEAGGADARPFITHHNTLDLPLYLRIATELHLKRLVVGGFERVY
ELGRIFRNEGVSTRHNPEFTSVEVYQAYADYLGMIELTESMIASVCEQVCGGTRLTYQGTEIDLTPPWRRATMHELVEEA
TGLDFTAFADRAAAAEAMTAKGLPVPDKADSVGRLLNEAFEHAVEANLIQPTFVLDYPEEISPLARKHRSKPGLVERFEL
FIVGRETANAFSELIDPVDQRGRLEAQQARRAAGDEEAQGVDEDFLQALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVI
AFPLLRPEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-103 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-84 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001223900.1 lysyl-tRNA synthetase VFG1668 Protein 2e-103 48