Gene Information

Name : metB (CMM_0873)
Accession : YP_001221613.1
Strain : Clavibacter michiganensis NCPPB 382
Genome accession: NC_009480
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 995583 - 996755 bp
Length : 1173 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
GTGAGCGACAAGCACGACTTCGACACCCGCGCGATCCACGCCGGACAGGACCCGGATCCCACCACGGGCGCGGTCATCCC
GCCGCTCTACCTCACGAGCACCTTCGTGCAGGACGGGATCGGCGGGCTCCGCGAGGGCTACGAGTACGCGCGGAGCGCCA
ACCCCACGCGCACCGGCCTGCAGGAGCTGCTCGCGTCGCTCGAGAAGGGGAAGCACGCGTTCTCGTTCGCCTCGGGGCTC
GCCGCCGAGGACACGCTGCTGCGCGCGATCACCCGCCCCGGCGACCGCATCGTGCTGAGCGACGACGTGTACGGCGGCAC
CTACCGCCTCCTCACGCGCGTGCTCGGCGACTGGGGGATCGTCGTCGAGACCGTCGACATGAGCGACCTCGCCGCGGTCG
AGCGGGTGCTCGGTTCCGGGCCGGCGAAGGTCCTCTGGGTCGAGACGCCCAGCAACCCGCTCATGAAGATCAGCGACATC
CGCGCGCTCGCCGACCTCGGCCACGCAGCGGGCGCCACGGTCGTCGTCGACAACACGTTCGCGTCGCCGTACCTCCAGCA
GCCGCTGACGCTCGGCGCCGACGTGGTCGTGCACTCGACCACCAAGTACCTGGGCGGCCACTCCGACGTGCTCGGCGGCG
CCGTGGTCCTCGACGACGACGCGCTCGCCGAGAAGGTCGGCTTCCTGCAGTTCGCGGTCGGCGCCGTCTCCGGCCCCATG
GACGCCTGGCTCACGACCCGCGGGATCAAGACACTCGCCGTCCGCGTCGAGCGCCACTCCGCGAACGCCGAGGAGATCGC
CGCCTTCCTGCAGCAGCACCCCGACGTCACGGCCGTGCACTACCCGGGCCTGCCGGAGCACCCGGGCCACGACATCGCCA
AGGCCCAGATGACGGGCTTCGGCGGCATGATCTCGTTCCAGGTGCGCGGGGGAGCGAAGGCCGCGCGCCGCGTGGTCGAG
GGCACGCGCGTGTTCCAGCTCGCGGAGTCGCTCGGCGGCGTCGAGTCGCTCATCAGCTACCCGTCCGAGATGACGCACGC
GTCCGTCAAGGGCACGCCGCTCGAGGTCCCTGGCGACCTGGTGCGCCTGTCGGTCGGCATCGAGTCCGTCGAGGACCTCG
TCGTCGACCTCGAGCGCGCGCTCGGCAAGGCCCTCAAGCAGGGCAAGCACTAG

Protein sequence :
MSDKHDFDTRAIHAGQDPDPTTGAVIPPLYLTSTFVQDGIGGLREGYEYARSANPTRTGLQELLASLEKGKHAFSFASGL
AAEDTLLRAITRPGDRIVLSDDVYGGTYRLLTRVLGDWGIVVETVDMSDLAAVERVLGSGPAKVLWVETPSNPLMKISDI
RALADLGHAAGATVVVDNTFASPYLQQPLTLGADVVVHSTTKYLGGHSDVLGGAVVLDDDALAEKVGFLQFAVGAVSGPM
DAWLTTRGIKTLAVRVERHSANAEEIAAFLQQHPDVTAVHYPGLPEHPGHDIAKAQMTGFGGMISFQVRGGAKAARRVVE
GTRVFQLAESLGGVESLISYPSEMTHASVKGTPLEVPGDLVRLSVGIESVEDLVVDLERALGKALKQGKH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-78 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-77 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-56 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_001221613.1 cystathionine gamma-synthase BAC0207 Protein 8e-67 43