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Name : cadA (RCIX2335) Accession : YP_686314.1 Strain : Methanocella arvoryzae MRE50 Genome accession: NC_009464 Putative virulence/resistance : Resistance Product : putative Cd(2+)-translocating P-type ATPase Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : 3.6.3.3 Position : 811244 - 813370 bp Length : 2127 bp Strand : + Note : - DNA sequence : ATGCACAAGCCGGAGCAGAAGAACGGCCGGGAGGCGTCGCCGGACGCCGCCCCGGGCCACATCGAAGTGCACACCTTCGA AATCCGGGGGCTGGACTGTGCAGACTGTGCGGCAAAGCTGGAAAAGTATGTCTCAGAGATGCCCGGAGTAGCCAGGGCAG CGCTAAACTTTTCTACGGCTGTTTTAACGGTAGAGCACTCGACCCCTGTAGCCGAGATTGGAAAAGCCATCTCGGGGATG GGGTACACTTACAAGCTGCAGGGCAACGGGAGCCCGAAGGAGAGCTTCCTGAGGAAGTACCGGAAAATCCTCTCGACGGC AGCATCGGGCATCGGCCTGGCTGCGGGAATGGCTGCGTCTTTCCTGGGACTGCCGTGGTACGTGCCGACGCTGTGCTTCG CCTTCGCTATTGTCACAGGCGGCTTCTATATCTTCAGAAGCGCGCTGTACTCGTTGAAATCGCTTACGCCGGACATGAAC CTGCTGATGACGCTCGCCGTAGCAGGGGCCATCCTGATCAACCAGTGGGAAGAAGGCGCCGCAGTCATCTTCCTGTTCTC GGTAGGGTCTGCGCTGCAATCGTACACCCTGGACCGGACGAGGAACTCGATCAAGTCGCTGATCAACCTCGCCCCCGCGG AAGCGTCTGTCCTCGTCGACGGAAAGGAACGGAAAGTCCCGGTGCGGTCGATCGTGCCCGGCGACATACTGATCATCAGG CCCGGCGAGCGCATCGCAATGGACGGCACTGTAGTAGATGGCGTCTCCTCGGTCAACCAGGCGCCCATCACCGGGGAATC GATCCCGGTGGAGAAAAGGAAGGGCAGCCCGGTATACGCGGGCACCATGAACGAGCGGGGCACGCTGGAAGTCGAAGTGA CGACGCTGTTCGAAGAGAACACCCTGTCGAAGATCATCCACATGGTCGAGGAAGCCCAGAGCCGCAAAGCCCCGGCGCAG GAGTTCGTGGACAGGTTCGCAAAATATTATACACCCGCAGTCATCCTGGTTGCAGCCGCCATCGCGACCATCCCCCCGCT CTTCGGGATGCCGTTCGATACCTGGTTCTACAGGGCGCTGGTGCTGCTGGTCATCGCCTGCCCGTGTGCGCTGGTTATCT CGACGCCCGTCTCAATTGTAGCCGCAATCGGCAACGCTTCGAGGCACGGCGTCCTCATCAAGGGCGGCACATACCTTGAA GAGTGCAGCCGCATCAAGGCCATCGCCTTTGACAAAACAGGCACTCTTACCGAGGGCAGGCCCGAAGTCACGGACGTAGT CACCTATGGCTGCAGCAGAGAGGAGGCCATCCACCTCGCCGCATCCATAGAGGACAGGTCTGAGCATCCGCTGGCGGCCG CCATCATGCGGGCCAACGGGAACAACGGAGTGCTTAAGGCAGAGTCGTTCGAGGCCGTGCCCGGGGCGGGAATCACGGCG ACAGTGAACGGAGTCCGGTATAGCATAGGCAGCGCCCGCATGTTCGAGAAACTGGGCGGCGAGGTGCAGGAAGCTATCGC AGCCTTTGAGGCTGCGGGTAAGACCCCGGTCATCCTGGGCGGGCCCCAGGGTATCCTCGCGGTCTTCGCCATCATGGACA GAGTCAGAGAGGAAAGCCCTGCTGCCCTTAAAGCGCTGCACGACGCCAGAGTCCCCCACCTGGTCATGCTCACCGGAGAC GGAGAGCAGGCGGCCAGGGCCATCGCCCGCCAGACCGGCGTAGACGAGTACTATGCAGGCCTACTACCGGAAGCGAAAGT GAGCCAGATCACCCGGCTCAGGCAAAAGTACGGGCACGTGGCGATGGTGGGCGACGGCGTCAACGATGCCCCCGCCCTCG CAGAGGCATCCATCGGCATAGCGATGGGCGCGACAGGCTCGGACACGGCCATCGAGACCGCGGACATCGCCCTGATGTCC AACGACCTCTCGAAGCTGTCGTACCTGGTCAAGCTTGGCCGCCGGATGATGAGCGTCATCAAGCAGAACGTGACCTTCTC GCTGGTGGTCAAGCTGCTCTTCATCGGGCTGACCCTGGCAGGCTTCTCCAACCTCTGGATGGCCGTGTTTGCCGACACCG GGGCGGCGATCATAGTGATCCTGAACGGGATGAGATTACTGCGGTAA Protein sequence : MHKPEQKNGREASPDAAPGHIEVHTFEIRGLDCADCAAKLEKYVSEMPGVARAALNFSTAVLTVEHSTPVAEIGKAISGM GYTYKLQGNGSPKESFLRKYRKILSTAASGIGLAAGMAASFLGLPWYVPTLCFAFAIVTGGFYIFRSALYSLKSLTPDMN LLMTLAVAGAILINQWEEGAAVIFLFSVGSALQSYTLDRTRNSIKSLINLAPAEASVLVDGKERKVPVRSIVPGDILIIR PGERIAMDGTVVDGVSSVNQAPITGESIPVEKRKGSPVYAGTMNERGTLEVEVTTLFEENTLSKIIHMVEEAQSRKAPAQ EFVDRFAKYYTPAVILVAAAIATIPPLFGMPFDTWFYRALVLLVIACPCALVISTPVSIVAAIGNASRHGVLIKGGTYLE ECSRIKAIAFDKTGTLTEGRPEVTDVVTYGCSREEAIHLAASIEDRSEHPLAAAIMRANGNNGVLKAESFEAVPGAGITA TVNGVRYSIGSARMFEKLGGEVQEAIAAFEAAGKTPVILGGPQGILAVFAIMDRVREESPAALKALHDARVPHLVMLTGD GEQAARAIARQTGVDEYYAGLLPEAKVSQITRLRQKYGHVAMVGDGVNDAPALAEASIGIAMGATGSDTAIETADIALMS NDLSKLSYLVKLGRRMMSVIKQNVTFSLVVKLLFIGLTLAGFSNLWMAVFADTGAAIIVILNGMRLLR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 3e-134 | 45 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 6e-134 | 44 |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 1e-130 | 43 |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 5e-119 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cadA | YP_686314.1 | putative Cd(2+)-translocating P-type ATPase | BAC0298 | Protein | 4e-123 | 45 |
| cadA | YP_686314.1 | putative Cd(2+)-translocating P-type ATPase | BAC0124 | Protein | 3e-86 | 43 |
| cadA | YP_686314.1 | putative Cd(2+)-translocating P-type ATPase | BAC0100 | Protein | 6e-68 | 41 |
