Gene Information

Name : serS (LRC224)
Accession : YP_684544.1
Strain : Methanocella arvoryzae MRE50
Genome accession: NC_009464
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 3039771 - 3041048 bp
Length : 1278 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACATCAGGTTCGTGAGAGAGAGCCCCGACGTGGTCAGGGCAGATCTCCGCAAGCGTAACGATCTCGAGAAGCT
CGCGTGGGTGGACGACCTCCTCGCGAAGGATTCCCAGGCCCGGGCAATGCAGGTCAAAGTAGACGAACTGCGCAGGCGCC
GCAACGAAATATCAAGGGAGATCAACGAGGCCCGGAAGGCTGGCAAGGATACCTCCGCCCTGATGGCCGAAGCCAGGGAC
ATTCCCAGGCAGATCAAGGAAGCGGAAACCGAGATGGAAGAGAGCCGGAACAAGGTGCACTACTACCTGATGCGCCTGCC
GAATATTCTGGACGACTCGGTCCCCGTCGGCAAAGATGACACGGAAAACGTGGAGGTCAAGCGCTGGGGCGAGCCCGTGC
AGAAGGACTTCGAGATCAAGAACCACGGGCTGCTGGCAGTCGAGCACGGCTGGGCCGACTTTGAGCGGGCAGCCAAGGTA
GCCGGAGCGGGCTTCTATTTCCTCAAGGGCAACATGGTGCTGCTGGACATGGCTCTGCAGCGGTTCGCGATGGACCTGCT
GGTCAAGAGAGGCTTCACCCCGGTCACCCCGCCGTACATGATGAACCGCAAGTCCTACGAAGGGGTCACAGATTTAGCCG
ACTTCGAGAAGGTCATGTACAAGATCGAGGGCGACGACATGTACCTGATCGCCACAAGCGAGCACCCCATCGGAGCAATG
TACCAGGGAGAGATATTTGAGGAGAAGGACCTGCCATTGAGGCTAGCCGGCATATCGCCCTGCTTCCGCAGGGAGATCGG
CGCCCACGGCCTCGACACCAAAGGCCTGTTCAGGGTCCACCAGTTCCACAAGATCGAGCAGTTCGTCTTCTGCAAGCCGG
AAGACTCGTGGAAGATTCACGAAGAGATCCTCGCCAACGCTGAGGCAGTCTTCCAGCAGCTGGGCCTGCCCTACCACGTA
GTCAACATCTGCACCGGCGACATCGGCACCGTAGCGGCCAAGAAGTACGACATAGAGGTCTGGATGCCGAGGGAGAACAC
GTACAAGGAAGTCGTCTCCTGCTCCAACTGCACCGCGTACCAGGCGACGAGGCTGAACATCAAGGTAAGGGATCCGAAGG
ACTTCGAGAGCAAGCGGTACGTCCACACCCTCAACTCCACGGCCATCGCGACGTCAAGGGCTATGAGAGCGATACTGGAG
AACAACCAGCAGAAAGACGGATCAGTCCTCATACCAGAGGTACTCAGGCCCTACATGAACGGGCTGGAGTACCTGTAA

Protein sequence :
MLDIRFVRESPDVVRADLRKRNDLEKLAWVDDLLAKDSQARAMQVKVDELRRRRNEISREINEARKAGKDTSALMAEARD
IPRQIKEAETEMEESRNKVHYYLMRLPNILDDSVPVGKDDTENVEVKRWGEPVQKDFEIKNHGLLAVEHGWADFERAAKV
AGAGFYFLKGNMVLLDMALQRFAMDLLVKRGFTPVTPPYMMNRKSYEGVTDLADFEKVMYKIEGDDMYLIATSEHPIGAM
YQGEIFEEKDLPLRLAGISPCFRREIGAHGLDTKGLFRVHQFHKIEQFVFCKPEDSWKIHEEILANAEAVFQQLGLPYHV
VNICTGDIGTVAAKKYDIEVWMPRENTYKEVVSCSNCTAYQATRLNIKVRDPKDFESKRYVHTLNSTAIATSRAMRAILE
NNQQKDGSVLIPEVLRPYMNGLEYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-69 43