Gene Information

Name : hemC (RCIX914)
Accession : YP_685587.1
Strain : Methanocella arvoryzae MRE50
Genome accession: NC_009464
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1946086 - 1946997 bp
Length : 912 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGGATAGGAACCAGGGGAAGCAAGCTGGCGCTGGCGCAGGCGGAGAAAGTCCGCCGCCTGCTCAAAGAGCAGGGCGT
GGAGGCCACAATTACGGTAATCAAGACCTCCGGGGACGTGCAGAAGGACAGTCCGCTGTACATGATGAAGGGCTATGGAG
CCTTCGTCCGGGAGATCGACGACTTACTGTTAAAAAACGAGGTCGACCTAGCCGTCCACAGCCTCAAGGACATCCCGACC
GTACGCCCGGAAAATCTGGTGACCGCCGCCGTGCTCAAGCGCGAGTCGGCGCTCGACGTGGCGGTGATCAGAAATGCAGA
GCGGCTGGCAGACCTGCCTGAAGGAGCGGTGGTGGGCACTTCCAGCACCCGCAGGGCGGCTATGATCTACCGCCACTACC
CCGGGCTCGTCACCAAGGACATCCGGGGCAACGTGGACACCCGGCTGCGCAAGCTCCGGGACGGAGAGTACGACGCGATC
CTCCTGGCAGAGGCCGGGCTGATCCGGCTGGGATTGGACTTGAAAGTAGAAAGACTTGACCCATACAACTTTGTCCCGGC
GGCCAACCAGGGCGTCATCGCCATCGTGGCCAGACAGGGCACTCCAGAAGCTGAAGTAGTCAAGGAACTGAACGACGAGA
CCACCTGGATTGAGACGAGGGTGGAGAGGATCATCGCCGCCGGCCTCGACGGAGGCTGCGTAGTCCCGATGGGCGTCTAC
GCGACCAGAGTCGGGGACGAGATCGACGTGATCGGCGAAGTGCTCTCTCTGGATGGCAGGCAGCAGGTCAGAGTAAGGGA
AACCATTCCCGTGGCCGGGTGCGAGGAACACGCGAAGCAAGTATCTGAAAAGCTCGTGCTGGCCGGCGGACTGAAGCTGG
CCGAAGAGGCCCGCAAGGAGCTGGACAGGTGA

Protein sequence :
MRIGTRGSKLALAQAEKVRRLLKEQGVEATITVIKTSGDVQKDSPLYMMKGYGAFVREIDDLLLKNEVDLAVHSLKDIPT
VRPENLVTAAVLKRESALDVAVIRNAERLADLPEGAVVGTSSTRRAAMIYRHYPGLVTKDIRGNVDTRLRKLRDGEYDAI
LLAEAGLIRLGLDLKVERLDPYNFVPAANQGVIAIVARQGTPEAEVVKELNDETTWIETRVERIIAAGLDGGCVVPMGVY
ATRVGDEIDVIGEVLSLDGRQQVRVRETIPVAGCEEHAKQVSEKLVLAGGLKLAEEARKELDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-37 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-37 43