Gene Information

Name : vibE (VC0395_A0301)
Accession : YP_001216257.1
Strain :
Genome accession: NC_009457
Putative virulence/resistance : Virulence
Product : vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 317892 - 319523 bp
Length : 1632 bp
Strand : -
Note : identified by match to protein family HMM PF00501; match to protein family HMM TIGR02275

DNA sequence : 
ATGACAACCGATTTTACCCCTTGGCCAGAGGCACTTGCCGCTCAATACCGTCAGTTAGGCTACTGGCAAGATAAAACCTT
GCTCGATTACTTACAGCAAAGTGCTGAGCGTACCCCCAATGCGCTTGCGCTGGTCGGTGATAATCAGCAGTGGCGTTACC
AAGCCATGCTCGAACGTATTGAGCAGCTTGCTGCCGGATTTACCGAACTTGGGCTAGGCTGTGGCGATAACGTAGTGCTG
CAATTAGGCAATGTTGCGGAATTCTATTTATGCTTTTTCGCTTTGCTGCGCCAAGGCATACGACCGATTCTGGCGCTCCC
CGCTCACCGTTTAGCGGAAATTCGCTATTTTTGTCAGCACAGCCAAGCCAAAGCTTACCTCATTGATGGCGCTCAGCGAC
CATTTGACTATCAAGCTTTGGCGCAAGAGCTGCTTGCTTGCTGCCCAACACTGCAGACTGTGATTGTACGCGGCCAAACT
CGAGTGACAGATCCAAAATTTATTGAACTGGCGAGTTGCTACTCGGCATCATCTTGTCAAGCGAATGCCGACCCGAATCA
AATCGCCTTTTTCCAACTTTCCGGTGGCACAACGGACACGCCCAAGCTCATCCCGCGTACCCACAATGATTACGCCTACA
GCGTAACCGCCAGTGTCGAAATTTGCCGTTTTGATCAGCATACTCGCTATCTGTGCGTACTGCCCGCGGCACATAACTTC
CCTCTCAGCTCCCCCGGCGCACTCGGTGTTTTCTGGGCGGGTGGCTGCGTTGTCCTCAGTCAAGATGCGTCACCCCAACA
CGCGTTTAAATTGATAGAACAGCATAAAATTACTGTTACCGCGTTGGTGCCGCCTTTAGCACTACTCTGGATGGATCACG
CAGAAAAAAGCACCTACGATCTCTCCTCATTGCACTTTGTGCAAGTAGGCGGGGCAAAATTTAGTGAAGCGGCCGCAAGG
CGTCTGCCGAAAGCGCTAGGCTGCCAATTGCAACAAGTGTTTGGAATGGCAGAAGGCTTGGTCAATTACACTCGTTTGGA
TGACAGTGCGGAACTGATTGCTACAACTCAAGGTCGGCCTATCTCCGCTCACGATCAATTACTGGTGGTTGATGAGCAGG
GTCAACCTGTCGCCAGCGGAGAAGAAGGGTATCTGTTAACCCAAGGTCCCTATACGATTCGCGGTTACTATCGAGCTGAT
CAGCACAATCAACGAGCGTTCAATGCACAAGGTTTTTACATCACCGGCGATAAAGTCAAACTCAGTAGCGAAGGTTACGT
GATTGTCACCGGAAGGGCCAAAGATCAGATCAATCGTGGAGGGGAAAAGATTGCCGCCGAAGAGGTGGAAAATCAGCTTT
TACATCATCCAGCAGTGCATGATGCCGCTTTAATTGCCATCAGTGACGAATACCTAGGAGAGCGCAGTTGCGCGGTGATC
GTACTCAAACCCGAGCAGTCGGTGAATACCATCCAGCTCAAACGTTTTTTACACCAAGCGGGGCTCGCCGATTACAAAAT
CCCAGATCAAATCCAATTTATCGATCAACTGCCCAAAACATCGGTTGGAAAAATCGATAAGAACGCGCTTCGTCGTCGAT
TTGACACGCTCGGCTTAGCGTTAATGTCGTGA

Protein sequence : 
MTTDFTPWPEALAAQYRQLGYWQDKTLLDYLQQSAERTPNALALVGDNQQWRYQAMLERIEQLAAGFTELGLGCGDNVVL
QLGNVAEFYLCFFALLRQGIRPILALPAHRLAEIRYFCQHSQAKAYLIDGAQRPFDYQALAQELLACCPTLQTVIVRGQT
RVTDPKFIELASCYSASSCQANADPNQIAFFQLSGGTTDTPKLIPRTHNDYAYSVTASVEICRFDQHTRYLCVLPAAHNF
PLSSPGALGVFWAGGCVVLSQDASPQHAFKLIEQHKITVTALVPPLALLWMDHAEKSTYDLSSLHFVQVGGAKFSEAAAR
RLPKALGCQLQQVFGMAEGLVNYTRLDDSAELIATTQGRPISAHDQLLVVDEQGQPVASGEEGYLLTQGPYTIRGYYRAD
QHNQRAFNAQGFYITGDKVKLSSEGYVIVTGRAKDQINRGGEKIAAEEVENQLLHHPAVHDAALIAISDEYLGERSCAVI
VLKPEQSVNTIQLKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKIDKNALRRRFDTLGLALMS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-95 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 8e-95 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-95 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-94 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-94 46
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 46
ybtE CAA21394.1 - Virulence HPI Protein 1e-94 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vibE YP_001216257.1 vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-121 50
vibE YP_001216257.1 vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 6e-119 48
vibE YP_001216257.1 vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 3e-103 44