Gene Information

Name : murD (VC0395_A1981)
Accession : YP_001217905.1
Strain :
Genome accession: NC_009457
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2125461 - 2126783 bp
Length : 1323 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGACCGTTGGCAAGGCATACAACATGTGGTCGTCGTGGGGCTCGGGATTACCGGGCTCTCTGTCGTTAATTATCTGCG
AAAATATCATCCGTCGGTAACCGTGCAGGTTATCGATACGCGCGAAATACCACCGGGGCAAGAGCAGCTTTCGTCGGACG
TTGCACTGCACCGTGGCGGGTGGAATCTTGAGTGGTTACTCAATGCCGATTTGGTAGTCACCAATCCAGGCATTGCGTTG
GCGACGCCGGAAATCCAACAAGTGCTGGCCGCTGGAATTCCTGTTGTCGGTGATATTGAGCTCTTTGCATGGCATGTGGA
TACACCCGTTATTGCGATCACTGGCTCGAACGGCAAAAGCACCGTCACTGATTTAAGTGGTGTGTTAGCCAATGCTGCTG
GTGTGAAGGCCGCGGTAGGCGGCAATATTGGGGTTCCGGCACTGGATCTGATTTCTCCAGACGTTGAACTGTATGTGCTT
GAGCTATCAAGCTTCCAATTAGAAACCACCTCTAGTCTAAAACTGAAAGCGGCTGCGTTTCTCAATCTTTCTGAAGATCA
TATGGATCGTTATCAGGGGATGGGAGATTACCGCCAAGCCAAACTGCGCATTTTCGATCATGCCGAAACCGCAGTGGTGA
ATGCCGATGATACTCAAACTTTTCCTGACCACGCGGCGCATCTGCAAGTGGTGACGTTTGGTGTCGAGCAAGCTGCACAA
TTTAGCCTTGCTCAACATCAAGGCCGCGAATACCTTTTTGCGCGCGATGAGGCCGTCATGGCGTGTGCTGAGCTGAGTTT
AGTTGGCCGTCATAACGTGACAAACGTACTTACCGTGTTAGCTTTGCTGGATTCAGCCGGAGTAAACTTCCGTTTGGCTT
TGGATGCACTCAAGTCTTACACGGGTTTGACACACCGCTGCCAAGTGGTTGCCGATAATCACGGCATCAAGTGGGTCAAT
GATTCTAAGGCGACCAATGTTGCGAGTACGCTGGCAGCATTGTCGGGATTAAAAATCGAAGGCCAGCTCTATTTGTTGGT
TGGTGGCGTAGGTAAAGGGGCGGATTTCACGCCGCTCGCCCCCGTATTGGCGACATTGCCTGTGCAATTGTGCTGCTTTG
GTGTGGACGGCCATCAATTTATGCCACTGCACCCTTCGGCTCGGTTTTATGACTCGATGGAGAGCATAATTCGCTCAATT
CGCCCGCAATTAAAAAGTGGGGATATGGTGCTGCTCTCTCCCGCTTGTGCGAGCTTTGATCAGTTCAAAAACTTTATGGC
GCGTGGGGATATTTTTGCCCAACTCGCTCGGCAATATGCATAA

Protein sequence :
MDRWQGIQHVVVVGLGITGLSVVNYLRKYHPSVTVQVIDTREIPPGQEQLSSDVALHRGGWNLEWLLNADLVVTNPGIAL
ATPEIQQVLAAGIPVVGDIELFAWHVDTPVIAITGSNGKSTVTDLSGVLANAAGVKAAVGGNIGVPALDLISPDVELYVL
ELSSFQLETTSSLKLKAAAFLNLSEDHMDRYQGMGDYRQAKLRIFDHAETAVVNADDTQTFPDHAAHLQVVTFGVEQAAQ
FSLAQHQGREYLFARDEAVMACAELSLVGRHNVTNVLTVLALLDSAGVNFRLALDALKSYTGLTHRCQVVADNHGIKWVN
DSKATNVASTLAALSGLKIEGQLYLLVGGVGKGADFTPLAPVLATLPVQLCCFGVDGHQFMPLHPSARFYDSMESIIRSI
RPQLKSGDMVLLSPACASFDQFKNFMARGDIFAQLARQYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-55 42
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-55 42