Gene Information

Name : aldA-2 (VC0395_A1414)
Accession : YP_001217357.1
Strain :
Genome accession: NC_009457
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1512348 - 1513868 bp
Length : 1521 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence : 
ATGATTTATGCACAACCGGGTAGTGACAACGCCGTTATCACCTTCAAGAGCCATTACGATAATTTCATTGGCGGCCAATG
GGTTAAACCTGTCAGTGGCGAATACTTTGGTAATATTTCACCCGTCAATGGACAGGTTTATTGCCAAGTCGCTCGCTCAA
CCCAAGCAGATATTGATTTGGCGTTAGATGCCGCACATCAAGTGCGTGAAGCATGGGCAAAAACCAGTGTGACTGAGCGC
TCTAACCTGCTACTGAAAATTGCTGATCGGATTGAAGCAAACATAGAGCAGCTTGCGGTAGCGGAATGCTGGGAGAATGG
TAAACCTGTGCGTGAAACTCTAGTGGCCGACCTCCCTCTGGTGGTTGACCATTTCCGGTATTTTGCAGGCTGTATTCGTG
CTCAAGAAGGCAGCGCCGCTGAGCTCGATAGCCACACGGCCAGTTACCATTTTCCTGAGCCAATCGGAGTGGTGGGACAA
ATCATTCCTTGGAATTTCCCAATGCTGATGGCAGCGTGGAAGTTAGCGCCAGCCCTTGCTGCAGGCTGCTGTGTGGTACT
CAAACCTGCCGAGCAAACCCCTACTTCGATCTTGGTGTTGATCGAAAAAATCGCCGATCTCATCCCAGCAGGCGTGCTCA
ACGTGGTCAACGGTTTTGGCAGTGAAGCAGGCCAAGCCTTGGCCACCAGTCAACGTATTGCCAAACTGGCGTTTACGGGC
TCAACCCAAGTGGGTCAACACATTCTCAAATGTGCGGCGCAGAGTTTAATTCCATCAACCGTAGAGCTCGGTGGGAAGTC
TCCTAATATCTATTTCCCAGATATTTTTGACCACGAAGACACCTATTTAGAGAAATGTATCGAAGGTACTTTGCTGGGCT
TTTTCAACCAAGGCGAAGTGTGTACTTGCCCTTCTCGCGTTCTGGTTCATGAGTCAATTTACGATCGCTTTGTGGCCAAA
GTCGCGGAGCGGGCGAAAGGCATCAAACAAGGCAATCCACTGGATACCGCTACTCAAGTAGGGGCTCAAGCATCTCAAGA
GCAGTTTGACAAGATCTTGAGTTACTTAGATATTGGCCGCCAGGAGGGCGCAAAAGTGCTGTTTGGTGGTGGCGTTGCCA
AACAGGAAGGGGAACTCGGTCAAGGCTACTATATTCAGCCGACCCTACTGCAAGGCCACAACAAGATGCGAGTCTTCCAA
GAAGAGATTTTTGGTCCTGTGATTGCCATTACCTCTTTTAAAGACGAAGCCGAAGCGTTGGCATTGGCTAACGATACCGA
ATACGGCCTCGGCGCAGGTATTTGGACTCGTGACCAAAACCTCGCCTACCGTATGGGAAGAAATATTCAAGCAGGCAGGA
TCTGGATCAACTGTTACCACGCTTACCCCGCGCATGCGGCCTTTGGTGGCTATAAAAAATCGGGTATTGGGCGTGAAACC
CACAAAATGATGTTGAACCACTACCAGAACACCAAAAACTTACTGATCAGCTACGATGTGAATCCTCTCGGTTTCTTCTA
A

Protein sequence : 
MIYAQPGSDNAVITFKSHYDNFIGGQWVKPVSGEYFGNISPVNGQVYCQVARSTQADIDLALDAAHQVREAWAKTSVTER
SNLLLKIADRIEANIEQLAVAECWENGKPVRETLVADLPLVVDHFRYFAGCIRAQEGSAAELDSHTASYHFPEPIGVVGQ
IIPWNFPMLMAAWKLAPALAAGCCVVLKPAEQTPTSILVLIEKIADLIPAGVLNVVNGFGSEAGQALATSQRIAKLAFTG
STQVGQHILKCAAQSLIPSTVELGGKSPNIYFPDIFDHEDTYLEKCIEGTLLGFFNQGEVCTCPSRVLVHESIYDRFVAK
VAERAKGIKQGNPLDTATQVGAQASQEQFDKILSYLDIGRQEGAKVLFGGGVAKQEGELGQGYYIQPTLLQGHNKMRVFQ
EEIFGPVIAITSFKDEAEALALANDTEYGLGAGIWTRDQNLAYRMGRNIQAGRIWINCYHAYPAHAAFGGYKKSGIGRET
HKMMLNHYQNTKNLLISYDVNPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-175 75
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 0.0 74
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 0.0 74
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 0.0 74
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 0.0 74

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA-2 YP_001217357.1 aldehyde dehydrogenase VFG0082 Protein 7e-176 75