Gene Information

Name : tktA-2 (VC0395_0565)
Accession : YP_001215404.1
Strain :
Genome accession: NC_009456
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 618853 - 620895 bp
Length : 2043 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGTTGAACGCACTCCGTTCAACCTCCTTTATTGAAATGAGTAACACTATGAATCGCAAACAACTTGCCAATGCTATCCG
CGCCCTGAGCATGGACGGCGTTCAAAAAGCTAACTCTGGTCACCCGGGAGCCCCAATGGGCATGGCGGATATCGCCGAAG
TGCTGTGGCGTTCACACTTAAACCACAACCCACAAAACCCAAATTGGGCTGACCGCGACCGTTTCGTACTGTCTAACGGC
CACGGCTCTATGCTGATTTACTCGCTGCTACACCTGAGCGGCTATGAGCTGTCGATTGACGATTTGAAAAACTTCCGTCA
ACTACACTCCAAAACACCGGGTCACCCAGAGTACGGTTATGCACCGGGCATCGAAACGACTACGGGCCCACTCGGCCAAG
GCATCACCAATGCCGTAGGTATGGCGATTGCTGAAAAAGCTCTGGCGGCGCAGTTCAACAAACCGGGTCACGACATCGTT
GACCACTTCACTTATGTGTTTATGGGTGACGGTTGTTTGATGGAAGGCATTTCGCACGAAGCGTGTTCACTGGCGGGCAC
ACTTGGCCTTGGCAAACTGATTGCGTTCTGGGATGACAACGGTATTTCTATTGATGGTCACGTGGAAGGCTGGTTCTCAG
ACGACACGCCAAAACGTTTTGAAGCGTACGGCTGGCATGTTATCCCTGCGGTTGATGGCCACGATGCAGATGCGATTAAC
GCTGCGATTGAAGCCGCGAAAGCAGAAACCTCTCGCCCAACGCTGATTTGTACCAAAACCATCATCGGTTTCGGCTCACC
AAACAAAGCGGGTTCACACGACTGTCACGGCGCACCTCTGGGCAACGATGAAATCAAAGCCGCGCGTGAATTCTTGGGTT
GGGAATACGCTCCGTTTGAAATCCCGGCTGACATCTACGCAGCGTGGGATGCAAAACAAGCAGGCGCAAGCAAAGAAGCC
GCTTGGAATGAGAAATTCGCCGCTTACGCGAAAGCTTACCCAGCCGAAGCTGCTGAATACAAACGCCGCGTAGCGGGCGA
GCTGCCAGCGAATTGGGAAGCCGCAACCAGCGAGATTATCGCTAACCTGCAAGCTAACCCTGCCAACATCGCATCGCGTA
AAGCATCACAAAATGCGCTGGAAGCGTTCGGCAAACTGCTGCCAGAATTTATGGGTGGTTCTGCTGACTTGGCGCCTTCT
AACCTCACCATGTGGTCTGGCTCTAAGTCACTGACAGCAGAAGATGCGTCAGGCAACTACATCCACTACGGTGTGCGTGA
GTTTGGTATGACGGCCATCATCAACGGTATCGCGCTGCACGGCGGTTTTGTCCCTTACGGTGCAACCTTCCTGATGTTTA
TGGAATACGCGCGTAACGCGATGCGTATGGCAGCACTGATGAAAGTGCAAAATATCCAAGTGTACACGCATGACTCTATC
GGTCTGGGTGAAGATGGCCCAACTCACCAACCAGTTGAGCAAATCGCTTCTCTGCGTATGACACCAAACATGAGCACATG
GCGCCCATGTGACCAAGTGGAATCGGCAGTGGCTTGGAAACTGGCCATCGAGCGTAAAGATGCGCCATCTGCGCTGATTT
TCTCGCGTCAAAACCTTGCGCAGCAACCACGCAGCGCAGAGCAAGTCGCGAACATCGCTAAAGGCGGTTACATCCTGAAA
GATTGTGCAGGCCAACCTGAGCTAATTCTGATTGCAACAGGCTCTGAAGTGGAACTGGCGGTTGCCGCTTACGAGCAACT
GAGCGCCGAAGGCAAAGCGGTTCGCGTGGTCTCTATGCCATCGACCGACGCATTTGATAAGCAAGATGCCGCTTACCGCG
AAGCCGTTCTGCCAGCGGCAGTCACCAAGCGTATCGCGATTGAAGCGGGTATTGCAGACTTCTGGTACAAGTACGTCGGC
TTTGGCGGTCGCATCATCGGTATGACCAGCTTCGGCGAATCAGCACCAGCCGGTGAGCTGTTCAAACTGTTTGGTTTCAC
GACTGAAAACGTAGTGAAACAAGCCAAAGAACTGCTGGCGTAA

Protein sequence :
MLNALRSTSFIEMSNTMNRKQLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRSHLNHNPQNPNWADRDRFVLSNG
HGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAIAEKALAAQFNKPGHDIV
DHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAIN
AAIEAAKAETSRPTLICTKTIIGFGSPNKAGSHDCHGAPLGNDEIKAAREFLGWEYAPFEIPADIYAAWDAKQAGASKEA
AWNEKFAAYAKAYPAEAAEYKRRVAGELPANWEAATSEIIANLQANPANIASRKASQNALEAFGKLLPEFMGGSADLAPS
NLTMWSGSKSLTAEDASGNYIHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSI
GLGEDGPTHQPVEQIASLRMTPNMSTWRPCDQVESAVAWKLAIERKDAPSALIFSRQNLAQQPRSAEQVANIAKGGYILK
DCAGQPELILIATGSEVELAVAAYEQLSAEGKAVRVVSMPSTDAFDKQDAAYREAVLPAAVTKRIAIEAGIADFWYKYVG
FGGRIIGMTSFGESAPAGELFKLFGFTTENVVKQAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 80
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 69