Gene Information

Name : lysS (DehaBAV1_0551)
Accession : YP_001214014.1
Strain : Dehalococcoides sp. BAV1
Genome accession: NC_009455
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 538496 - 539992 bp
Length : 1497 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCCGGAAGAATATTTAAACGCTCAAAAGATGGAAAAACTTGAACGGATAAAGAGCCGGGGTATCAACCCTTATCCGTC
CACTTTTCATCCCAGCCATACCAGCGCACAGGCAGTTGCTTTGCTGGTTGAGATTGAAACACAGGAAAATCATCTGAAGG
AAGTCCTTAAGCTTGCCGGACGGATAATGACCCGCCGTGATATGGGCAAGATTTCCTTTATGGATATACGTGACGGCAGT
GGTAAAATGCAGATTTTTTTCCGTCAGAATGACCTTGACGAAGCCAGTATAGAACTGCTTAAAGACTTGGATTTGGGTGA
TTTTATCGGGGTAGAGGGTAGCCTGATGCGTACCCGCACTGGTGAGCCCAGTCTGGCTGCTACCAAAGTAAGTATGCTTT
CAAAATCACTCCTGCCTCTGCCTGAGAAATGGCACGGCCTGCAAGATGTAGAGAAACGCTACCGCCAGCGTTACCTTGAC
CTGATTTCCAACGCAGATGCCCGCCAGACCTTCCTGACCCGCAGCCGGGTTATCAGTGTTATACGTGCCTTTATGAATGC
TAAAGGGTTTCTGGAAGTAGAAACACCTGTTCTTCAGCCTGAGGCAGGCGGGGCACTTGCACGCCCGTTTATTACCCATC
ATCAGGCTTTGAACTGTGATTTTTATATGCGAATAGCTCTGGAACTGCACCTGAAAAGGCTGATAGTGGGCGGTTTTGAC
CGGGTGTATGAAATTGGGCGTATTTTCCGTAACGAAGGCATCTCCACCAGGCATAACCCCGAATTTACCATGATGGAAAG
CTACCAGGCTTACGCTAACTATAAAGACGTTATGGATTTTCTTGAGGAAATGGTTTCAAGCGTGGTCAAAGAGATTAGCG
GTGGATACACCCTGCCGTTTGGAGATATTACCTTGGACTTTACTCCCCCGTGGCCCCGCCTGACCATGCGTGATGCTGTA
AAACAATATGCCGGCATAGACTTTTTTGATTTCCCCACCAAAGAAACACTGGCAGCAGAAATGACCCGCCGCAAACTCAA
AGTAGATCCCGCCAAAGACTGGGGGAAACTGGTAGATGAGCTGGTAGGTGAATTTGTAGAACCCCACCTTGTTCAACCCA
CTTTCCTTACTGACCACCCTGTGGCCATGTCTCCCCTTGCCAAACAGAAACCGGAAGACCCCCGCCTGACAGAGCGGTTT
GAGGCCATCTGCGCAAATATGGAAATAGCCAACGCTTTTTCCGAACTGAATGACCCGGTAGAGCAAAGGGCACGTTTTAA
AGAACAGCTTGAAAAACGCAGTCAGCTACGCACGGACGAATCTGAAAGCGTGGATGAAGACTTTTTGGCCGCTCTGGCAT
ACGGTATGCCGCCCACCGGCGGTCTGGGTGTGGGTATTGACCGTCTGGTGATGCTCTTTACCAACCATGACTCTATCCGC
GAGGTTATTCTATTTCCTGCCCTGAAGGACCGGGAAGACACTAAAACACAGGAATAA

Protein sequence :
MPEEYLNAQKMEKLERIKSRGINPYPSTFHPSHTSAQAVALLVEIETQENHLKEVLKLAGRIMTRRDMGKISFMDIRDGS
GKMQIFFRQNDLDEASIELLKDLDLGDFIGVEGSLMRTRTGEPSLAATKVSMLSKSLLPLPEKWHGLQDVEKRYRQRYLD
LISNADARQTFLTRSRVISVIRAFMNAKGFLEVETPVLQPEAGGALARPFITHHQALNCDFYMRIALELHLKRLIVGGFD
RVYEIGRIFRNEGISTRHNPEFTMMESYQAYANYKDVMDFLEEMVSSVVKEISGGYTLPFGDITLDFTPPWPRLTMRDAV
KQYAGIDFFDFPTKETLAAEMTRRKLKVDPAKDWGKLVDELVGEFVEPHLVQPTFLTDHPVAMSPLAKQKPEDPRLTERF
EAICANMEIANAFSELNDPVEQRARFKEQLEKRSQLRTDESESVDEDFLAALAYGMPPTGGLGVGIDRLVMLFTNHDSIR
EVILFPALKDREDTKTQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-109 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001214014.1 lysyl-tRNA synthetase VFG1668 Protein 2e-109 47