Gene Information

Name : leuS (PTH_0839)
Accession : YP_001211389.1
Strain : Pelotomaculum thermopropionicum SI
Genome accession: NC_009454
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 845968 - 848451 bp
Length : 2484 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAAAGAAAGATACGACTTTAAAGAAATAGAAGAAAAGTGGCAGGCCCGCTGGGCTGCGCAAGACCTTTACGCGGTACC
GGATTATTCAGACCGGCCGAAGTATTACTGCCTTGAAATGTTTCCGTACCCGTCTGGCAAGCTGCATATGGGCCACGTCA
GGAACTACTCCATCGGCGATGTGGTGGCCCGCTTTAAAACCATGCAGGGCTATCACGTGCTTCACCCCATGGGCTGGGAT
GCATTCGGGCTGCCCGCCGAAAACGCCGCCATCAAGCACGGCGGGGTACATCCCGCCGAATGGACCCTGGACAATATCGA
GAGCATGCGCGCCCAGCTTAAACAACTGGGCATCAGCTATGACTGGAACAGGGAAGTGGCGACCTGCCATCCGGGCTACT
ACCGCTGGACGCAGTGGCTTTTCCTGCAGCTTTTCCATAACGGCCTGGCCTATAAAAAGAAGGCGGCGGTAAACTGGTGC
CCCGGCTGCGCTACGGTGCTGGCCAACGAGCAGGTAAAGGACGGGGGCTGCGAGCGGTGCAAGGCTCCGGTGGAAAAGCG
GGAGCTGGAACAGTGGTTCTTTAAAATTACCGACTACGCCGAGCGCCTGCTAAAGGACCTGGAACTGCTGGAAGGCTGGC
CGGAAAAGGTTAAAATCATGCAGGAAAACTGGATCGGCCGCAGCGAGGGTGCGGAAATAGATTTCAAAGTGGAAGGCTCG
GACGATATCATAACTGTATACACCACGCGGCCGGATACCGTTTTTGGCGTCACCTACATGGTTTTGGCACCGGAACACCC
GCTGGTGGAAAAGCTGATTGCCGGTTCAAAGCAGGAAGCCGAGATTAAGGAATTTATCCGGAAGGTAAGGAATTTGAGGG
AGATAGACCGGACCTCCACCGAGGCGGAAAAGGTCGGCATGCCCACCGGGGCGCACTGCATCAACCCCTTGACCGGGGAA
AAGGTGCCCGTCCTGATTGCCAACTACGTCCTGATGGAATACGGCACGGGCTGCGTCATGGGGGTACCCGCCCACGACCA
GCGGGACTTTGAATTTGCCCGGAAGTACGGCTACCCGATCCGGGTGGTCATTCAGCCGCCGGGCGTCGAACTGGACCCCG
CTGCCATGGAAGCCGCTTATGAGGAAGAGGGCTTTCTGGTCAACTCCGGCCCGTTCAGCGGCATGCCCAACAAGGAGGCA
ATCAGGGCCATTACCCGCCACCTGGAAGAAAAAGGCCGGGGAAGGTTCCGCGTAACCTACCGCCTGCGGGACTGGCTCAT
TTCGCGTCAGCGTTACTGGGGGGCTCCCATCCCCATCATTTACTGCGACCGGTGTGGCACGGTCCCCGTGCCCGAGTCCG
ATTTGCCGGTGCTGCTGCCCATGGACGTTGAATTTAAACCTACCGGGCAGTCGCCCCTGGCCGAGTGCCCGGAATTCGTA
AACGCCGCCTGCCCCAGTTGCGGCGGGCCCGGCAAAAGGGAAACCGACACCATGGACACCTTCATGTGCTCGTCCTGGTA
TTACTACCGCTATACCAGTCCCAGGGACAACGACGCCCCCTGGGACAGGAACAAGGTGGACTACTGGCTGCCGGTGGACC
AGTATATCGGCGGGGTGGAGCACGCCATTCTGCACCTTTTGTATTCCCGCTTTTTTACCAAGGTGCTCTACGACCTGAAG
CTGGTGAGCAACCTGGAACCGTTTTCCAACCTGCTCACACAGGGCATGGTGTTAAAGGACGGGGCCAAGATGTCCAAATC
CAGAGGCAACGTGGTCAGCCCGGAGGATATCGTGGCCCGTTACGGAGCCGATACCGCCCGGCTGTTTATCCTTTTTGCCG
CTCCGCCGGAGCGCGATCTGGAATGGAGCGACCAGGGGGTGGAGGGGTGCTACCGGTTTTTGAACCGGGTCTGGCGCCTG
GTAATGCCCCTGGCCGGCCTGCTGAAAGAGGCGCCGGCGGCCGTTTCCGGCAAACTGGTGGGGGCAAACCGGGAGATGCG
CCGGGTTACCCACAGCACCATAAAAAAGGTAACCGAAGACATAAGCGCCCGCTTCAACTTCAACACCGCCGTCAGCGCCA
TCATGGAACTGGTCAACGCCCTTTACCAGTTCAGGGAAATACCGGAATCTGACCGCAACCCGGCGGTGCTGCGGGAAGCG
GTGGAGTCCCTGCTGCTTCTGCTGGCCCCCTTTGCGCCCCACATCACCGAAGAGCTGTGGGAGGCCACCGGGCACAGGGG
CAGCATTCACCTGCAGCCCTGGCCGTCTTACGATCCGGAGGCCATTGCGGAAGACGAAATAACCATCGTGGTGCAAATCA
ACGGCCGGGTGCGCGAACGCCTGCTGGTGCCCGCCGGAATAACCCCGCAGGAAATGCAGGACAGGGTAATGAAAGAGCCC
AGGGTGATGCGGATGGTTGAAGGGAAAAAAGTTGCAAAGGTTATAACTGTTCCAGGTAAACTTGTTAACATTGTGATAAA
GTAG

Protein sequence :
MKERYDFKEIEEKWQARWAAQDLYAVPDYSDRPKYYCLEMFPYPSGKLHMGHVRNYSIGDVVARFKTMQGYHVLHPMGWD
AFGLPAENAAIKHGGVHPAEWTLDNIESMRAQLKQLGISYDWNREVATCHPGYYRWTQWLFLQLFHNGLAYKKKAAVNWC
PGCATVLANEQVKDGGCERCKAPVEKRELEQWFFKITDYAERLLKDLELLEGWPEKVKIMQENWIGRSEGAEIDFKVEGS
DDIITVYTTRPDTVFGVTYMVLAPEHPLVEKLIAGSKQEAEIKEFIRKVRNLREIDRTSTEAEKVGMPTGAHCINPLTGE
KVPVLIANYVLMEYGTGCVMGVPAHDQRDFEFARKYGYPIRVVIQPPGVELDPAAMEAAYEEEGFLVNSGPFSGMPNKEA
IRAITRHLEEKGRGRFRVTYRLRDWLISRQRYWGAPIPIIYCDRCGTVPVPESDLPVLLPMDVEFKPTGQSPLAECPEFV
NAACPSCGGPGKRETDTMDTFMCSSWYYYRYTSPRDNDAPWDRNKVDYWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLK
LVSNLEPFSNLLTQGMVLKDGAKMSKSRGNVVSPEDIVARYGADTARLFILFAAPPERDLEWSDQGVEGCYRFLNRVWRL
VMPLAGLLKEAPAAVSGKLVGANREMRRVTHSTIKKVTEDISARFNFNTAVSAIMELVNALYQFREIPESDRNPAVLREA
VESLLLLLAPFAPHITEELWEATGHRGSIHLQPWPSYDPEAIAEDEITIVVQINGRVRERLLVPAGITPQEMQDRVMKEP
RVMRMVEGKKVAKVITVPGKLVNIVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-174 45