Gene Information

Name : ClpA (PTH_2122)
Accession : YP_001212672.1
Strain : Pelotomaculum thermopropionicum SI
Genome accession: NC_009454
Putative virulence/resistance : Virulence
Product : ATPase with chaperone activity, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2229363 - 2231978 bp
Length : 2616 bp
Strand : -
Note : -

DNA sequence :
ATGAGACTGGATAAACTCACTTTAAAGACCCAGGAAGCTTTTGAGGCCGCCCAGAGGCTGATGGCCCAGTACAGCCACCA
GCAGATGGAAGGGGTGCACCTGCTGCTGGGCCTGCTTCAGCAGGAGGAAGGTATTGTCAGGCCGGTTTTGCAAAAGCTGG
AAGTGGATGTCAATAAATTAAAAGCCCAGGTTCAGGCTGCGGTGGAGCGCCTGCCCAGGGTGCACGGCGCCGGGGGGGTT
TACGTTTCCCAGGAGCTCTCCCGGATCATCGATCTGGCCTGGAAGGAAGCGGAGAGGTTTAAGGACGAGTACCTGAGCAC
GGAGCACATCCTGCTGGGGATGGTTGGCCTGCGTGAAGGAGAGGCGGGCAGAATCCTGCGTTCCAGCGGGGTAACCCAGG
ATCGCCTGTACAGAGCCCTGGCCGAAATCCGCGGCAGCCAGCGGGTGACCGATCAGAACCCGGAAGACAAATACCAGGCG
CTGGCCCGCTTTACCAGGGATCTCACCGAACTGGCCCGCAAGGGCAAACTTGACCCGGTTATCGGCAGGGACGAAGAAAT
TCGCCGGGTCATTCAGGTGCTTTCCAGGCGCACCAAGAACAACCCGGTCTTAATCGGCGAGCCCGGCGTGGGCAAGACGG
CCATAGTGGAGGGGCTGGCCCAGCGGATCATGAGCGGCGACGTGCCGGAAAGCCTGAAAAACAAGCGCCTTTTGAGCCTG
GACATGGGCGCGCTGATCGCCGGATCGAAGTACCGGGGCGAGTTTGAAGACAGGATGAAGGCGGTTTTGAAGGAAATAAA
CGACGCTCACGGCGAGATCGTGCTGTTCATCGACGAACTGCACACCCTGGTGGGCGCCGGGGCGGCAGAGGGGGCGGTGG
ACGCGGCCAATATGCTCAAGCCGGCCCTGGCCCGGGGCGAGCTGCGCTGCGTGGGAGCCACCACCCTGGACGAGTACCGC
AAGCACATCGAGAAGGATGCCGCCCTGGAGCGGCGCTTCCAGCCGGTCTATGTAGGTGAGCCCGGCGTGGAGGACACCAT
TGCCATACTGAGGGGCTTGAAGGAAAAATACGAAGTGCACCACGGGGTGCGGATCAAGGACGCGGCCCTGGTGGCGGCGG
CCATGCTTTCCCACCGCTACATTTCCGACCGCTTCCTGCCTGACAAGGCCATCGACCTGGTGGATGAGGCGGCTTCCCGC
CTGCGCATCGAGATCGACAGCATGCCCACCGAGATTGACGAGATCGACCGGCGGATCCGGCAACTGGAGATCGAAAAGCA
GGCCCTGGCCAAGGAACAGGACAAGGGCAGCCAGGAAAGGCTTCAAAAGATTGAAGGAGAACTGGCCGCGCTTAAGAGCA
GGCTGGAGGATTTAAAGGAACACTGGCGAAAAGAAAAAGAGTTAATCCAGAGCATCCGGGAAATAAAGGAGAGGATTGAG
GAAACCAGGCTGGCGGAGCAAGCCGCCGAGCGGGAAGCCGACCTGGGCAAGGTGGCCGAATTGCGCTACGGCGTAATGCC
TGAGCTGAACAGGCGCCTGCAGCAGAACAACGAAAAACTGGCGGAGTTGCAAAAGGCCCATAAAATGCTGAAGGAGGAAG
TGGACGAGGAGGACATCGCCGAAGTGGTGGCCAAGTGGACCGGCATTCCGGTAAGCCGCATGCTGGAAGGGGAGGTCCAG
AAACTGCTTAAAATGGAGGAACTGCTGAAAGAGCGGGTGGTCGGGCAGGACCGGGCGGTAAAGGCGGTGTCCGACGCCAT
CCGCCGGGCCAGGGCCGGCGTGGCCGACCCGAACCGGCCCATGGGTTCCTTCATCTTCCTGGGGCCCACCGGCGTGGGTA
AGACCGAGCTGGCCAGGGCCCTGGCGCACTTCCTCTTCAACGACGAGCGGGCCATGCTCCGTTTCGACATGAGCGAGTAC
ATGGAGAAGCACGCCGTCTCCCGTCTCATCGGCGCCCCGCCGGGCTACGTGGGCTACGACGAGGGCGGGCAGCTCACCGA
GGCTGTAAGGCGCCGGCCCTATGCGGTAATTCTCTTTGACGAGATAGAAAAGGCCCACCCGGACGTGTTCAACATCCTGC
TGCAACTCCTGGACGACGGCCGCCTTACCGACGGGCACGGCCGCACGGTGGACTTCAAAAACACGGTGGTGATCATGACC
TCCAACCTGGGCAGCCACTGGTTCCGGGAGATTAATTTGAAAAACCGGGCCGAGCTGGAAGCGCGGGTAATGGACGAGCT
GAAGGCCAGCTTCCGTCCCGAGTTTTTGAACCGCATTGACGAGGTGGTGATATTCAACAATCTGGGCAAGGAAGAGCTCA
TCAAGATTGTGGATATCCAGCTGAACCTGCTTAAGGCGAGGCTGGCCAAACTGGGCCTGACCCTGGAGGTGACTCCGGAG
GTCAAGGCGCTCCTGGCGGAAGAAGGGTTCGACCCGGTGTACGGGGCCCGTCCCCTGAAGCGGGCCATCCAGCGCCGCCT
GGAGAATCCTCTTTCCGTGCACATTCTGGAAGGAAAGCATGCCCAGGGAGACAGCATCCTGGTGACGGTGGATAAGGCTA
CCGGCAGCCTGACCTTCCAGAGCCGGTCATCTGCTCAGGCGGGGCAGCCTGCCTGA

Protein sequence :
MRLDKLTLKTQEAFEAAQRLMAQYSHQQMEGVHLLLGLLQQEEGIVRPVLQKLEVDVNKLKAQVQAAVERLPRVHGAGGV
YVSQELSRIIDLAWKEAERFKDEYLSTEHILLGMVGLREGEAGRILRSSGVTQDRLYRALAEIRGSQRVTDQNPEDKYQA
LARFTRDLTELARKGKLDPVIGRDEEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIMSGDVPESLKNKRLLSL
DMGALIAGSKYRGEFEDRMKAVLKEINDAHGEIVLFIDELHTLVGAGAAEGAVDAANMLKPALARGELRCVGATTLDEYR
KHIEKDAALERRFQPVYVGEPGVEDTIAILRGLKEKYEVHHGVRIKDAALVAAAMLSHRYISDRFLPDKAIDLVDEAASR
LRIEIDSMPTEIDEIDRRIRQLEIEKQALAKEQDKGSQERLQKIEGELAALKSRLEDLKEHWRKEKELIQSIREIKERIE
ETRLAEQAAEREADLGKVAELRYGVMPELNRRLQQNNEKLAELQKAHKMLKEEVDEEDIAEVVAKWTGIPVSRMLEGEVQ
KLLKMEELLKERVVGQDRAVKAVSDAIRRARAGVADPNRPMGSFIFLGPTGVGKTELARALAHFLFNDERAMLRFDMSEY
MEKHAVSRLIGAPPGYVGYDEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNILLQLLDDGRLTDGHGRTVDFKNTVVIMT
SNLGSHWFREINLKNRAELEARVMDELKASFRPEFLNRIDEVVIFNNLGKEELIKIVDIQLNLLKARLAKLGLTLEVTPE
VKALLAEEGFDPVYGARPLKRAIQRRLENPLSVHILEGKHAQGDSILVTVDKATGSLTFQSRSSAQAGQPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-100 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-98 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ClpA YP_001212672.1 ATPase with chaperone activity, ATP-binding subunit VFG2076 Protein 1e-115 46
ClpA YP_001212672.1 ATPase with chaperone activity, ATP-binding subunit VFG2084 Protein 4e-100 44