Gene Information

Name : FliI (PTH_2085)
Accession : YP_001212635.1
Strain : Pelotomaculum thermopropionicum SI
Genome accession: NC_009454
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2193856 - 2195196 bp
Length : 1341 bp
Strand : -
Note : -

DNA sequence :
TTGGAGAGCTTCTCAATAGACATTTCTCACTGGAGGTCCCGCCTGAAGGAGGCCAGACTGTTAAGGCTTACCGGGCAGGT
TACCAGGGTTATCGGGCTAACTGTCGAGGTTAAGGGGATAAACGCATCGATAGGTGAAGTGTGTGAGATTACCGTGCCCG
GCGAGCCGGAGCCGGTACGGGCCGAAGTGGTGGGCTTCCGCGACGGAAGTACGCTTTTGATGCCGCTGGGCGAACTCAAG
GGGATTTACCAGGGGTGCAGCGTTACCCCCAGCGGCCGGCCGTTTACCATCAAGGTGGGAGAAGGGCTTCTGGGCAGGGT
GCTGAACGGGCTGGGCGAACCCATGGACGGCCTTGGCCCTGTGGGCGGGCGCACCGAAAATTACCCGGTTGACAACCGCC
CTCCCAATCCCCTGAAGAGAAGGCGAATTACCGAGGTCCTGTCAACCGGAGTGCGGGCGGTGGATGGCCTGCTTACCTGC
GGCAGAGGCCAGCGGATCGGCATATTTTCCGGCAGCGGGGTCGGCAAAAGCACCCTTCTGGGAATGGTTTCCCGTTTCAG
CGACGCCGACGTCAACGTTATCGGGCTTATCGGGGAGCGGGGGCGGGAGGTCCTGGATTTTATCGAGACTGACCTGGGTC
CGGAAGGCCTGGCCCGTTCGGTCGTGGTGGTGGCCACGTCGGAGCAGCCGGCGCTGGTGCGCCTGAAAGGAGCCTTTGTG
GCCTGTGCAGTGGCCGAGTACTTCCGCGATCAGGGCAGGGACGTGCTTTTAATGATGGACTCCATAACCAGGTTTGCCAT
GGCCCAGCGGGAGGTCGGCCTGGCCATCGGGGAACCGCCGGCTACCAAGGGGTACACCCCCTCAGTGTTCGCCCTGCTCC
CCCGCCTTCTCGAGCGGGCCGGAATGTCAAGCGCCGGCTCAATAACCGCGTTTTTCACCGTCCTGGTGGACGGGGACGAC
TTAAACGAGCCTATCTCCGACGCGGTGAGGGGCATCCTGGACGGGCACATCGTCCTGTCACGCTCCCTGGCAGCGTCCAA
CCACTTTCCGGCGGTAGACGTGTTGAACAGCGTCAGCCGGCTAATGCCCGACATAACAACGGAGGAACACCGGGCCTGGG
CCGGCAGGCTGCGCGATTTGCTGGCGGCCTACCGCCAGGCCGAGGATCTGATAAACATAGGCGCCTACGTGGCCGGCTCA
AACCCGCGCGTGGATGAAGCAATAGCCTGTTACCAGGATATTGTTGCATTCCTGCGGCAGGATTTGAAAGAACATGCCCG
TTTTGAGGAAACCCTTGCGATGCTTGAGAAAATAGTTAATAGAGGAGTGAATGGGCAGTAG

Protein sequence :
MESFSIDISHWRSRLKEARLLRLTGQVTRVIGLTVEVKGINASIGEVCEITVPGEPEPVRAEVVGFRDGSTLLMPLGELK
GIYQGCSVTPSGRPFTIKVGEGLLGRVLNGLGEPMDGLGPVGGRTENYPVDNRPPNPLKRRRITEVLSTGVRAVDGLLTC
GRGQRIGIFSGSGVGKSTLLGMVSRFSDADVNVIGLIGERGREVLDFIETDLGPEGLARSVVVVATSEQPALVRLKGAFV
ACAVAEYFRDQGRDVLLMMDSITRFAMAQREVGLAIGEPPATKGYTPSVFALLPRLLERAGMSSAGSITAFFTVLVDGDD
LNEPISDAVRGILDGHIVLSRSLAASNHFPAVDVLNSVSRLMPDITTEEHRAWAGRLRDLLAAYRQAEDLINIGAYVAGS
NPRVDEAIACYQDIVAFLRQDLKEHARFEETLAMLEKIVNRGVNGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-105 54
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-102 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-102 54
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-101 54
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-101 54
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-102 54
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-103 54
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-103 54
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-101 54
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 8e-102 54
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-91 53
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-84 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-84 52
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-84 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-84 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-84 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-87 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-87 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-78 48
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-86 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-86 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-86 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-86 47
escN AAL57542.1 EscN Virulence LEE Protein 2e-86 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-86 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-86 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-86 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-84 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-86 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-86 47
escN AAC38383.1 EscN Virulence LEE Protein 3e-86 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-86 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-75 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-82 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-83 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-83 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-85 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-80 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-82 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-75 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-79 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-79 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-74 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-74 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-76 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-73 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-72 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-72 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-72 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0390 Protein 3e-108 54
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2144 Protein 8e-111 53
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0192 Protein 9e-103 53
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0048 Protein 3e-107 52
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1254 Protein 1e-99 52
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0515 Protein 3e-84 52
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2331 Protein 8e-94 50
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2499 Protein 1e-99 49
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0730 Protein 2e-86 47
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0812 Protein 9e-87 47
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1778 Protein 1e-75 45
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2459 Protein 5e-78 43
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0555 Protein 3e-72 42
FliI YP_001212635.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1008 Protein 8e-76 42