Gene Information

Name : SerS (PTH_0013)
Accession : YP_001210563.1
Strain : Pelotomaculum thermopropionicum SI
Genome accession: NC_009454
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 16565 - 17833 bp
Length : 1269 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATATGAAGTTCGTGCGGAACAACCCGGCAGCGGTCAGGGATGCCCTTGCCAGGCGAGGCGTTTCGGTGGCCCT
GGACGAATTTTATAAATTGGACGAAGAGCGCCGGGAAAAGCTCTTTATCGTGGAGCAGATGAAAAACAGGCGCAACGTCG
TTTCCGAGGAGATCGGCCGGCTGAAAAAATCCGGCAAGGACGCGCCGGAAATGGTCCTGGAAATGCGGGACCTGTCCCGG
CAGATCAAGGAAATCGACGAGGAAATAAAGGAACTTGACGGCAGGCTGCAGGACATGCTGCTCAACATTCCCAACATTCC
CCATGAATCCGTACCGGAAGGTGCCGGCGCGGCGGAGAACCCCGTGGTGCGCACCTGGGGAAAGCCGCGGGATTTTGGTT
TCACGCCCAGGCCCCACTGGGAGATAGGCGAGCAGCTTGATATTATAGATTTCGAACGGGGCGGCAAGGTGGCCGGGGCC
AGGTTCAGCTTTTATAAGGGTTACGGGGCCCGCCTGGAGCGGGCAGTAATCAATTTCATGCTGGACCTGCACACTGCCGA
ACACGGCTACGTGGAAATATTCCCGCCCTTCATCGTAAACCGCGACAGCATGGTGGGAACCGGGCAATTGCCTAAGTTTG
CCGAGGACATGTTTAAGCTGGAGGGTGCCGAATATTACCTTATACCCACCGCCGAGGTGCCGGTGACCAATCTTTACCGC
AACGAAATACTGGACGGCGAAAAGCTGCCCATTTTGCATTGCGCTTACAGCGCCTGCTTCAGGGCCGAAGCCGGGGCCGC
CGGCCGGGATACTCGCGGCCTGATCCGCCAGCACCAGTTCAACAAGGTGGAGCTGGTCAAATTCTGCCGGCCGGAGGATT
CCTATGACGAGCTGGAGAAGCTGACCGCGGACGCCGAAAAAGTGCTCCAGAAACTGGGGCTTCCCTACCGGGTGGTGGTC
CTGTGCACCGGGGATCTGGGCTTTTCGGCGGCAAAGACGTACGACCTGGAAGTCTGGCTGCCCAGCTACCAGGAGTACAA
AGAGATTTCTTCCTGCAGCAACTTCGCCGATTTTCAGGCCCGCCGGGCCGGCATCCGCTTCCGGAACGCCAGGGGCAAAA
CCGAGTTCGTACACACCCTGAACGGTTCGGGGCTGGCCGTAGGCCGCACGGTTGCCGCCATTTTAGAAAATTACCAGGAG
GCCGACGGCTCGGTGACCGTCCCCGAGGCCCTGCGCCCCTATATGGGCGGCTTGAGCCGGATCGGCTGA

Protein sequence :
MLDMKFVRNNPAAVRDALARRGVSVALDEFYKLDEERREKLFIVEQMKNRRNVVSEEIGRLKKSGKDAPEMVLEMRDLSR
QIKEIDEEIKELDGRLQDMLLNIPNIPHESVPEGAGAAENPVVRTWGKPRDFGFTPRPHWEIGEQLDIIDFERGGKVAGA
RFSFYKGYGARLERAVINFMLDLHTAEHGYVEIFPPFIVNRDSMVGTGQLPKFAEDMFKLEGAEYYLIPTAEVPVTNLYR
NEILDGEKLPILHCAYSACFRAEAGAAGRDTRGLIRQHQFNKVELVKFCRPEDSYDELEKLTADAEKVLQKLGLPYRVVV
LCTGDLGFSAAKTYDLEVWLPSYQEYKEISSCSNFADFQARRAGIRFRNARGKTEFVHTLNGSGLAVGRTVAAILENYQE
ADGSVTVPEALRPYMGGLSRIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-121 62