Gene Information

Name : hemC (PTH_0972)
Accession : YP_001211522.1
Strain : Pelotomaculum thermopropionicum SI
Genome accession: NC_009454
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 997298 - 998236 bp
Length : 939 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAGCGGGAGATTGCAGTGGGCACCAGGGTAAGCAAGCTGGCCATGTGGCAGGCCCGGTGGGTGGTAGACCGCCTGAA
GGAGCTCTGCCCCGGTTGCAGCTTCCGGATTGTAGGAATCCGTACCCTGGGCGACCGTATCCTTGACGCGGCCCTTGTTA
AAATAGGAGATAAGGGCCTTTTTACTAAAGAACTGGAAGCGGCCATGCTGCGCGGGGAAATCGACATGGCGGTGCACAGC
ATGAAGGACCTGCCCACCGAACTGCCCGAAGGCCTGGTCATAGGTGCCGTGTGCAAGAGGGAACACCCGGCCGACGTGCT
GGTTTCCCGCCGGGGCAAAAAGCTGGATGAGCTGCCCGGAGGGGCGCTTGTCGGCACCAGCAGCCTCAGGCGCTGCGCCC
AGCTTTTGTGGTACCGCGACGATCTCAGGATGGTAAACCTGCGGGGGAACATCAACACCCGCTTGCGCAAGCTGGAGGAG
GAGAATCTGGACGCCGCCGTGCTGGCTTATGCCGGCCTGTTCAGGATGGGCCGGCAGGACGCAATTACCCAGGTTATTCC
CTTCGACATTTGCCTGCCGGCGGTGGGCCAGGGTTCGATTGGGGTGGAGGTGCGCAGCGATGACGGGGAAGTGCTGGAGC
TGGTGAAAAAGATAGATCACCGGGAATCCCGCCTGGCCGTTTTTGCCGAAAGGGCCTTTTTAAGAAGGCTGGAGGGCGGG
TGCCAGGTTCCCGTCGGCGCCCTGGGAACGGTGGAAAACGACCGGCTGCGCCTGGAGGGGGTGGTCGCCACCCCGGACGG
AAAGCAGCTTGTGCGTTCATTTGTGGAGGGAAACGGCGGCGACGCCGCCGCAATTGGGTTAAGGCTGGCGGAGAAGCTCC
TGGAGCTGGGGGCGGGGGAAATTTTAAAAAGGGCAAGGCAGGAGGAAAGACGTGAGTAA

Protein sequence :
MKREIAVGTRVSKLAMWQARWVVDRLKELCPGCSFRIVGIRTLGDRILDAALVKIGDKGLFTKELEAAMLRGEIDMAVHS
MKDLPTELPEGLVIGAVCKREHPADVLVSRRGKKLDELPGGALVGTSSLRRCAQLLWYRDDLRMVNLRGNINTRLRKLEE
ENLDAAVLAYAGLFRMGRQDAITQVIPFDICLPAVGQGSIGVEVRSDDGEVLELVKKIDHRESRLAVFAERAFLRRLEGG
CQVPVGALGTVENDRLRLEGVVATPDGKQLVRSFVEGNGGDAAAIGLRLAEKLLELGAGEILKRARQEERRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-57 49
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-57 49