Gene Information

Name : pilR (DNO_0435)
Accession : YP_001209349.1
Strain : Dichelobacter nodosus VCS1703A
Genome accession: NC_009446
Putative virulence/resistance : Virulence
Product : two-component response regulator PilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 473960 - 475546 bp
Length : 1587 bp
Strand : +
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954

DNA sequence :
ATGAATCACGCGTTAGTTGTTGATGATGAAAAAGATATCTGCGAATTAATTGAAATGGCATTAATGGGACAATATATTGA
ATTTAAAAGCGCTTTTAATGTTAAAACGGCGATTAAATTATTAAAAGAAAATCGTTTTGACGTTGTTTTTTGTGATGTGC
GTTTGCCTGATGGCGACGGTCTCGATCTGCTCGCCCATATTCAAAAACAATATCCCAATACGCCCGTATGCATGATAACG
GCGCACGGCAATATGGATATGGCAATTCGGGCGTTGAAAATCGGCGCTTTTGATTTTATTAATAAACCTTTTGAATTGAA
ACAGTTACGCACAATTTGCCGTTCAGCGTTAAGCAGTCAACCTAAAAATAAAAAAGATAACGGGGAACCGCGAAAAACGG
CATTAATCGGCGAGGCACCGGTGATGGAAAAAGTGCGGGCATTGATTGCAAAAGTCGCGCGGTCGCAAGCGCCGGTATTT
ATTCACGGCGAATCGGGTACGGGAAAAGAAGTTGCCGCGCGGTCAATTCACGAACAAAGTAACCGCGCCGACGGCGCTTT
TATTGCCGTTAACTGCGGTGCAATTCCGGAAAATTTAGTGGAAAGTGAATTTTTTGGTTATAAAAAAGGTTCATTTACCG
GCGCTAATCAAGATACGGATGGGTTATTTGTTGCTGCAAATGGCGGTACGCTTTTTTTAGATGAAGTTGCAGATTTGCCG
TTATCGATGCAAGTAAAATTGTTGCGCGCGATTCAAGAGCGGGCGGTGCGTCCGATTGGCGGCGATAAAGAGGAAAAGGT
TGACGTGCGCATTATTTCGGCAACGCACGATAATTTGGCAGAAAAAGTGCAATTGGGCGAATTTCGCGAGGACTTGTATT
ACCGTTTAAACGTTGTTGCATTAACGATGCCGCCGCTGCGCGATCGCACGGGCGATGTCAATATATTGACAGATTTTTTG
TTAAAAAAATTAGCCGAACAACGCGGTTATCCGTTAGCGAAATTAACCGATGAAGCGCTTAATAAATTAAATTCTTATGC
TTTTCCGGGCAATGTGCGCGAATTGGAAAACATTTTGGAGCGCGCGCTGACTTTTATGGACGGAGAACAAATTGAAGCCG
AAGATATTCATCTTAATCTTGCATTGCAAGCGGCGATGAAACCGGCGGCAACCAATGAGGAAGAGGATATCTTTTTCGGC
ATTGAAACGAAATCTAATAAAGAAACGGAACCCAACGAAAATAACGATGGCGGTTTTCAAAATAATATTGGCTACGTTAG
CAATAATCCGCCGCCGCTCAACGCGTTTTCTTTCCAATTTCACGATGAACAAACAAAGCAAACAACGGCGCCTTCATCTC
AAACGCCGCCGCCAACGATTCAAAAATCTTCCGAACGCGTACATAAATCAGATGAAAAAGCGCAGGAAATGCCCGACGAT
CTCGAAGGGTTTATGCAAGAAATGGAGCGCAAATTGTTGATTAAAGCCTTAAAAGAAAACGGCAACAATAAAACGAAAGC
CGCCGAATCTTTGGGCATTAGTTTTCGGGCAATGCGTTATAAATTAAAAAAATTAGGAATTGATTGA

Protein sequence :
MNHALVVDDEKDICELIEMALMGQYIEFKSAFNVKTAIKLLKENRFDVVFCDVRLPDGDGLDLLAHIQKQYPNTPVCMIT
AHGNMDMAIRALKIGAFDFINKPFELKQLRTICRSALSSQPKNKKDNGEPRKTALIGEAPVMEKVRALIAKVARSQAPVF
IHGESGTGKEVAARSIHEQSNRADGAFIAVNCGAIPENLVESEFFGYKKGSFTGANQDTDGLFVAANGGTLFLDEVADLP
LSMQVKLLRAIQERAVRPIGGDKEEKVDVRIISATHDNLAEKVQLGEFREDLYYRLNVVALTMPPLRDRTGDVNILTDFL
LKKLAEQRGYPLAKLTDEALNKLNSYAFPGNVRELENILERALTFMDGEQIEAEDIHLNLALQAAMKPAATNEEEDIFFG
IETKSNKETEPNENNDGGFQNNIGYVSNNPPPLNAFSFQFHDEQTKQTTAPSSQTPPPTIQKSSERVHKSDEKAQEMPDD
LEGFMQEMERKLLIKALKENGNNKTKAAESLGISFRAMRYKLKKLGID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 3e-84 49
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 3e-84 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_001209349.1 two-component response regulator PilR VFG1214 Protein 6e-100 57
pilR YP_001209349.1 two-component response regulator PilR VFG1249 Protein 6e-66 42