Gene Information

Name : thyA (BRADO5578)
Accession : YP_001207467.1
Strain : Bradyrhizobium sp. ORS278
Genome accession: NC_009445
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 5761728 - 5762522 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCACCAGTATCACGACCTGCTCGAACGCATTTTGTCCGATGGCGCGCAGAAGCACGACCGCACCGGCACCGGCACGCT
GTCCGTGTTCGGCCATCAGATGCGCTTCAACCTCGCCGCCGGCTTCCCGATGGTCACCACCAAGCGGTTGCCGCTGAAGG
CGATCGTGCACGAGCTGCTGTGGTTTCTGAAGGGCGACACCAACATCAAATATCTGCACGACCACGGAGTCACCATCTGG
GACGAGTGGGCCGATGCCAACGGCGATCTCGGTCCCGTCTACGGCTACCAGTGGCGCTCCTGGCCGACGTCGGACGGCGG
CCAGATCGACCAGATCAGCAATGTCGTCGACATGATCCGGCGCAACCCGGATTCGCGCCGGCTGATCGTCACCGCGTGGA
ATCCGGCCGACGTCGAGAAGATGGCGCTGCCGCCGTGCCACTGCCTGTTCCAGTTCTACGTGGCCAATGGCAAGCTGTCC
TGCCAGCTCTATCAGCGCTCGGCCGACGTCTTCCTCGGCGTGCCCTTCAACATCGCCTCCTATGCGCTGCTGACGATGAT
GGTGGCGCAAGTGACGGGGCTGAAGCTCGGCGAGTTCGTGCACTCGTTCGGCGACGTGCATCTCTATTCCAACCACATCG
AGCAGGCCCGCCTGCAACTGAGCCGAACCCCGCGGCCGCTGCCGACCATGACGCTCAATCCCGACGTGAAGGACATCTTC
GCCTTCCGCTATGAGGATTTTGCGCTCGCCGGCTACGATCCGCATCCGCACATCAAGGCCGAGGTCGCGGTCTAG

Protein sequence :
MHQYHDLLERILSDGAQKHDRTGTGTLSVFGHQMRFNLAAGFPMVTTKRLPLKAIVHELLWFLKGDTNIKYLHDHGVTIW
DEWADANGDLGPVYGYQWRSWPTSDGGQIDQISNVVDMIRRNPDSRRLIVTAWNPADVEKMALPPCHCLFQFYVANGKLS
CQLYQRSADVFLGVPFNIASYALLTMMVAQVTGLKLGEFVHSFGDVHLYSNHIEQARLQLSRTPRPLPTMTLNPDVKDIF
AFRYEDFALAGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 7e-85 65