Gene Information

Name : guaA (BRADO3169)
Accession : YP_001205202.1
Strain : Bradyrhizobium sp. ORS278
Genome accession: NC_009445
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3373161 - 3374768 bp
Length : 1608 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGCCCCAGCCAACAATACCCCCGCCGCCGCCGCCACCGACACCTCCGTGGCCGCGCTCCACGACAAGATCCTGAT
CGTCGATTTCGGCAGCCAGGTCACGCAGCTGATCGCGCGCCGGGTGCGCGAGGACGGCGTGTATTGCGAGATCGTGCCGT
TCCAGAAGGCGGAGGCCGCCTTCCGGCAGATGAACCCGAAGGCCGTGATCCTGTCCGGCGGCCCCGAATCCGTCCACGAG
GAAGGCTCGCCGCGCGCCCCGCAGCTGATCTTCGAGTCAGGCGTCCCCGTGATGGGCATCTGCTACGGCCAGATGACGAT
GGCCGCCCAGCTCGGCGGCACCGTCGAGGGCGGTCACCACCGCGAGTTCGGCCGCGCCGACGTCGAGGTGAAGACCAACA
GCCTGCTGTTCGACGGCGTCTGGCAGCCGGGTGAGCAGCACCAGGTGTGGATGAGCCATGGCGACCGCATCACCCAGATG
CCGCCGGGCTTCTCGGTCGCCGGCGTCTCGCCGAACGCGCCGTTCGCCGTGATCCAGGACGAGGCGCGCAAATATTACGG
CCTGATGTTCCACCCCGAGGTGGTGCACACACCCGACGGCGCCAAGCTGATCCGCAACTTCGTCCGCAACATCTCAGGCC
TCGGCGGCGACTGGACCATGCACGCCTTCCGCGAGGAGGAGATCAAGAAGATCCGCGCCCAGGTCGGCCAGGGCAAGGTG
ATCTGCGGTCTCTCCGGCGGCGTCGATTCCGCTGTCGCCGCGGTGCTGATCCACGAGGCGATCGGCGACCAGCTCACCTG
CGTCTTCGTCGACCACGGCCTGCTGCGCCTGAACGAGGCCGAGACCGTCGTCGACCTGTTCCGCCACCACTACAACATCC
CGCTGGTGCATGTGGACGCCTCAAAGCTCTTCCTCGGCGAGCTCGCAGGCGTCACCGACCCGGAAGCGAAGCGCAAGACC
ATCGGAAGGCTCTTCATCGACGTGTTCGAGGCCGAGGCCAAGAAGATCGGCGGCGCCGATTTCCTGGCGCAGGGCACGCT
CTATCCCGACGTGATCGAGAGCGTCTCCTTCACCGGCGGCCCCTCGGTGACGATCAAGTCGCACCACAATGTCGGCGGCC
TGCCGGCGCGCATGAACATGAAGCTGGTCGAGCCGCTGCGCGAGCTGTTCAAGGACGAGGTCCGCGTGCTCGGCCGCGAG
CTCGGCCTCCCCGACGTCTTCGTCGGCCGCCACCCGTTCCCGGGCCCCGGCCTCGCCATCCGCTGCCCCGGCGAGATCAC
GACAGACAAGCTCGACATCCTGCGCAAGGCCGACGCCATCTACATCGACGAGATCCGCAAAGCCGGCCTCTACGACACCA
TCTGGCAGGCCTTCGCCGTGCTGCTCCCCGTCAAGACCGTCGGCGTCATGGGCGACGGCCGCACCTACGACTACGTCGTC
GGCCTGCGCGCGGTCACCTCGACGGATGGCATGACGGCGGACTTCTATCCGTTTGATATGAAGTTCTTAGGGAATACGGC
GACGCGCATCATCAACGAGGTGAAGGGCGTGAACCGGGTGGTGTATGACGTGACGAGCAAGCCTCCGGGAACGATTGAGT
GGGAGTAG

Protein sequence :
MTAPANNTPAAAATDTSVAALHDKILIVDFGSQVTQLIARRVREDGVYCEIVPFQKAEAAFRQMNPKAVILSGGPESVHE
EGSPRAPQLIFESGVPVMGICYGQMTMAAQLGGTVEGGHHREFGRADVEVKTNSLLFDGVWQPGEQHQVWMSHGDRITQM
PPGFSVAGVSPNAPFAVIQDEARKYYGLMFHPEVVHTPDGAKLIRNFVRNISGLGGDWTMHAFREEEIKKIRAQVGQGKV
ICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRLNEAETVVDLFRHHYNIPLVHVDASKLFLGELAGVTDPEAKRKT
IGRLFIDVFEAEAKKIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPARMNMKLVEPLRELFKDEVRVLGRE
LGLPDVFVGRHPFPGPGLAIRCPGEITTDKLDILRKADAIYIDEIRKAGLYDTIWQAFAVLLPVKTVGVMGDGRTYDYVV
GLRAVTSTDGMTADFYPFDMKFLGNTATRIINEVKGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-132 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-132 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-132 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-120 52