Gene Information

Name : leuS (SSU05_2081)
Accession : YP_001199447.1
Strain : Streptococcus suis 05ZYH33
Genome accession: NC_009442
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1982572 - 1985091 bp
Length : 2520 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGACATGGAGAAATGACATGAGCTTCTATAATCACAAGGAAATCGAGCCCAAATGGCAAGAATTTTGGGCAAAAAATCA
TACTTTTAAGACAGGAACAGATGCAGAAAAGCCAAACTTTTATGCCCTAGATATGTTCCCTTATCCGTCTGGTGCGGGCT
TGCACGTTGGTCACCCTGAGGGCTATACGGCGACGGACATTCTCAGCCGTTACAAGCGTGCCCAAGGTTACAACGTTCTT
CACCCAATGGGTTGGGATGCCTTTGGTCTGCCAGCTGAGCAATACGCTATGGATACAGGCAATGACCCAGCTGACTTTAC
GGCGGAAAATATTGCCAACTTCAAACGTCAGATTAACGCCCTTGGCTTTTCTTACGACTGGGACCGCGAGGTTAATACGA
CTGACCCTAACTACTACAAGTGGACTCAGTGGATTTTCACCAAATTGTATGAAAAAGGCCTAGCCTATGAGGCAGAAGTG
CCTGTAAACTGGGTAGAAGAATTGGGAACAGCTATCGCCAACGAAGAGGTCCTTCCTGACGGAACGTCTGAACGTGGTGG
TTATCCAGTTGTCCGCAAGCCAATGCGCCAATGGATGTTGAAAATAACGGCCTATGCAGAGCGTTTGCTTAATGACTTAG
AAGAAGTTGATTGGCCAGAGTCTATCAAGGATATGCAACGCAACTGGATTGGCAAGTCTACGGGTGCCAATGTGACTTTC
AAGATTAAGGACACAGATAAGGACTTCACAGTCTTTACTACCCGTCCTGACACCCTTTTCGGTGCGACCTACGCAGTCCT
TGCCCCTGAGCATGACTTGGTAGATAGTATCACATCAGCTGAACAAGCAGAAGCTGTGGCAGAATACAAACGCCAAGCCT
CTCTCAAATCAGACCTGGCTCGTACTGACCTGGCTACAGACAAGACCGGTGTCTGGACAGGTGCTTATGCCATCAACCCT
GTCAACGGTAAAGAAATTCCAATCTGGATTGCCGACTATGTACTGGCAAGCTACGGAACAGGTGCTATCATGGCCGTTCC
TGCTCATGACGAGCGTGACTGGGAATTTGCCAAACAGTTTGGTTTGGACATTATTCCAGTTCTGGAAGGTGGCAATGTAG
AAGAAGCTCCTTACACAGAGGACGGTGCCCACATCAATTCTGATTTCCTAGATGGTCTTAACAAGGAAGAAGCTATTGCC
AAAATGGTAGCTTGGTTGGAAGAAAACGGTGTCGGTCAGGAGAAGATTTCTTACCGCCTCCGCGACTGGCTCTTCAGCCG
CCAGCGTTATTGGGGTGAGCCAATTCCAATCATCCACTGGGAAGATGGAACTTCCACAGCCGTACCAGAAAATGAGTTAC
CTTTGGTATTGCCAAAAACCTCAGACATCAAGCCTTCAGGTACAGGGGAGTCACCTCTTGCTAACTTGACAGACTGGTTG
GAAGTGGTGCGTGAAGACGGTGTTAAAGGTCGCCGTGAAACCAACACTATGCCACAATGGGCGGGTTCTAGCTGGTACTA
CCTCCGCTATATCGACCCGCACAATGATGAGAAATTGGCAGACGAGGATCTTCTCAAAGCTTGGTTGCCAGTGGACATCT
ACATCGGTGGTGCTGAGCACGCAGTCCTTCACCTGCTCTACGCTCGCTTCTGGCACAAGTTCCTTTACGACCTTGGCGTT
GTGCCGACCAAAGAGCCATTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACTAGCTACCGCGACAGCCGTGGTGC
CCTTGTAGCGACAGATAAAGTTGAAAAACGCGATGGGTCCTTCTTCCACATGGAAACTGGTGAAGAGTTGGAGCAGGCAC
CTGCTAAGATGTCTAAGTCTCTTAAAAACGTGGTTAACCCAGATGATGTGGTCGAGCAATTCGGTGCGGACACTCTCCGT
GTTTATGAAATGTTCATGGGTCCACTTGATGCGTCAATCGCTTGGTCAGAAGAAGGTCTCGAAGGCAGCCGTAAGTTCCT
TGACCGTGTCTATCGCCTCTTAACCACTAAGGAGCTTGTGGCGGAAAATAGCGGAGCGCTTGATAAAGTTTACAATGAAA
CTGTGAAGACGGTGACAGAGCATATTGAAGACCTGAAATTCAACACAGCTATCGCCCAGCTCATGATTTTTGTCAACGCA
GCCAACAAGGAAGACAAGCTTTATGTTGACTACGCCAAAGGTTTTGTCCAATTGATCGCCCCATTTGCACCACACTTGGC
AGAAGAACTCTGGCAGGGTCTTGCAAATACAGGCCAGTCAATCAGCTATGTCGCATGGCCAACATATGACGAAAGCAAGC
TGGTAGAAAGCGAAGTGGAAATCGTTGTCCAAATCAAAGGCAAGGTAAAAGCTCGCTTGACCGTAGCCAAAGACTTAGCA
CCAGCTGAACTTGAAAAAGTTGCCCTTGCAGATGAAAAAGTCCAAGCTGAAATAGCTGGTCAAACAGTGGTGAAGGTGAT
TAGTGTTCCGAATAAACTAGTTAATATTGTTGTGAAATAA

Protein sequence :
MTWRNDMSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVL
HPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEV
PVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANVTF
KIKDTDKDFTVFTTRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLATDKTGVWTGAYAINP
VNGKEIPIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIPVLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIA
KMVAWLEENGVGQEKISYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWL
EVVREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLLYARFWHKFLYDLGV
VPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLR
VYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNA
ANKEDKLYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIKGKVKARLTVAKDLA
PAELEKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90