Gene Information

Name : guaA (Fjoh_2377)
Accession : YP_001194723.1
Strain : Flavobacterium johnsoniae UW101
Genome accession: NC_009441
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2846242 - 2847771 bp
Length : 1530 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAACACAACGTACTTATTTTAGATTTCGGATCGCAATATACTCAGCTTATTGCGCGTAGAGTTCGCGAATTAAATAT
ATTCTGCGAAATTTTTCCTTACAATCACATTCCAAGTGATTTATCAAGTTATAAAGCCGTAATTTTAGGAGGAAGCCCTT
TCTCTGTTAGAGGAGAAGATGCGCCGCATCCTGATTTATCACAAATTAGAGGTAAAATGCCTTTGCTTGCTGTTTGTTAC
GGAGCTCAATATTTAGCTCATTTCAGCGGTGGAGAAGTGGCAGCTTCTAATACAAGAGAATACGGAAGAGCAAATTTGTC
TTATATTAAAGAAGGCGAGACTTTCTTCGAAGGAGTTTCAGAAAACAGCCAGGTTTGGATGAGCCACAGCGATAGTATCA
AAGCGCTTCCAACAAATGCTGTAAAATTAGCAAGCACGCATGACGTAGAATACGCAGCTTATAAAATTGAAGGCGAAACT
ACTTATGCTATTCAATATCACCCAGAAGTTTACCATTCAACAGATGGTAAAAAAATGCTGGAAAACTTCTTGGTAAAAAT
TGCTGAAGTTCCTCAAAACTTTACTCCAAATGCTTTCGTTGACGAAATGGTGGCAGAATTAAAAGAAAAATTAGGAAACG
ATAAAGTGGTTCTTGGTTTATCTGGAGGAGTAGATTCTACTGTAGCAGCAGTTTTATTAAACAAAGCAATCGGACAAAAT
TTATATTGCATCTTCGTTAACAACGGACTTTTACGTAAAAACGAATTCCAAAATGTATTAGATCAATACAAAGGAATGGG
ATTAAATGTAAAAGGTGTAGATGCCGGAGATCGTTTCCTTGGCGAATTAGCAGGAATCAGCGATCCAGAAACAAAACGTA
AAACAATTGGTCGTGTATTTATCGAAGTTTTTGATGATGAATCACACTTATTAGAAGACGTAAAATGGTTAGCGCAGGGA
ACAATTTACCCAGACGTAATTGAGTCTGTTTCGGTAAAAGGACCATCAGCAACTATTAAATCGCACCACAATGTGGGTGG
ATTGCCGGATTATATGAAATTAAAAATTGTAGAACCGCTTAGAATGTTGTTTAAAGACGAAGTTCGTAGAGTTGGAGCTA
CATTAGGAATAGATCCTGAATTATTAGGAAGACACCCTTTCCCAGGACCAGGATTATCAATTAGAATTTTAGGAGATATT
ACGCCGGAGAAAGTACAAATTTTACAAGATGTCGATTCTGTATTTATAGAAGGATTAAAATCTTGGGGATTATATGACAA
AGTTTGGCAGGCGGGAGCCATTTTGCTTCCAGTAAACAGTGTTGGAGTTATGGGCGATGAGCGTACTTACGAAAAAGTAG
TAGCGCTTAGAGCAGTAGAATCAACAGATGGTATGACTGCTGACTGGGTTCACTTACCGTATGATTTCTTGATGAAAGTA
TCAAATGATATTATCAATAAGGTAAAAGGCGTGAATCGTGTAGTTTACGATATTAGTTCAAAACCACCTGCAACAATTGA
GTGGGAATAG

Protein sequence :
MQHNVLILDFGSQYTQLIARRVRELNIFCEIFPYNHIPSDLSSYKAVILGGSPFSVRGEDAPHPDLSQIRGKMPLLAVCY
GAQYLAHFSGGEVAASNTREYGRANLSYIKEGETFFEGVSENSQVWMSHSDSIKALPTNAVKLASTHDVEYAAYKIEGET
TYAIQYHPEVYHSTDGKKMLENFLVKIAEVPQNFTPNAFVDEMVAELKEKLGNDKVVLGLSGGVDSTVAAVLLNKAIGQN
LYCIFVNNGLLRKNEFQNVLDQYKGMGLNVKGVDAGDRFLGELAGISDPETKRKTIGRVFIEVFDDESHLLEDVKWLAQG
TIYPDVIESVSVKGPSATIKSHHNVGGLPDYMKLKIVEPLRMLFKDEVRRVGATLGIDPELLGRHPFPGPGLSIRILGDI
TPEKVQILQDVDSVFIEGLKSWGLYDKVWQAGAILLPVNSVGVMGDERTYEKVVALRAVESTDGMTADWVHLPYDFLMKV
SNDIINKVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-106 45
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-106 45
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-106 45
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-106 45