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Name : lysS (Msed_2161) Accession : YP_001192224.1 Strain : Metallosphaera sedula DSM 5348 Genome accession: NC_009440 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 2075586 - 2077076 bp Length : 1491 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTTGGCTATGAAATGGGACGAGAGGAGAATCCAAGTTTTAGAGGAACTTAGAGCTCGCGGAGTAAACCCTTACCCACA GAAATATCCAATTACTCACACGGTAGTTCAGTTGAGACAGATAGGGAACCAGAGACAGGACAAGCCCAAGGATCCCTTCC TTACAGGAGTTAGGACAGCTGGAAGGGTGGCCAATCTCAGAAGGCACGGGAAAGCCTCGTTCGTCGATATATTTGATGAT GGGGAGAAACTTCAGCTATACCTGAGGGTAAATGAGCTTGGTGACAAGTATGAGTATTTCTTCAAGGTCGTGGATAGGGG AGACATAATAGGCATTCAGGGGGATCTGTTTTTCACGGCAAAGGGAGAGCTAACACTGCTGGTTAAGGATTTTGCCATGC TTGCCAAATCCTTGATAGAGCCCCCTGATTGGTCTACGATGAGCCCGGAGTTTAGGTATTCCCACAGATACGTTGATTTC CTATATAACGACAATGCGAGAAGGTTTATGGAAACCAGGTTCAAGATCATCAGGGAAATAAGGAACATACTTGGAGAGGA GGGTTTTATTGAGGTGGAGACTCCAATTCTTCAACCTGTGTATGGAGGTGCCCTGGCTAGACCTTTCAAATCTCACGTTA ACTACCTTAATGAGGACTGGTACCTCAGAATCTCCTTGGAACTTTATCTGAAGAGGTTCATTGTGGGAGGCTTCAATAAG GTCTTTGAGATCGGAAAGGTATTCAGGAACGAGGATATAGATGTCACTCACAACCCAGAGTTCACGCTCATGGAGCTATA CTGGGCCTACGCTGACTATAACGATATCATGGATCTCACAGAGAGGTTATTCAAACAGCTAGCTGATAGGGTTCTTCACT CCACCAAGATACCCTACAAGGTTGGGGAGAAAACTGTGGAGATCAACCTGGAAAGCTTCAGGCGCGTCTCCATGTACGAT TCCCTGTCAGAGGCCCTTGGGAAGAACGTGGAGGAGATGACCGATGACCAGCTTAAGGAATTGATGCAGAGGAACGGGCT GGTTCCAAGGGGTTCACTGTATATCCGAGGTCTTATGATCGAGAAGTTATTTGATAAACTCGTCACACCTAGCCTAGTTC AACCTACTTTCGTGACTGACTATCCCATAGAGACTACCCCACTTTGCAAGCCTCACAGAAATAAGCCAGGACTTGTGGAG AGATTCGAGCTCTACATTGCAGGAGTGGAATTCGCCAATGCCTACACGGAGCTCAACGATCCCATTTTACAGGACAAGCT GTTCAGGGAAGAGCAGGACATGATGAAACGTGGCGACCAAGAGGCACATCCCTACGATAAGGATTTCATAAACGCCTTAA GTTACGGTATGCCACCCACGGGAGGCTTGGGGATTGGTATTGACAGGCTCGTGATGCTTTTCACCAATAACCAGAGCATA AAGGAAGTTATTCCATTCCCCATGGTCAGCTCGAAGCTTATTGAGGAATAA Protein sequence : MLAMKWDERRIQVLEELRARGVNPYPQKYPITHTVVQLRQIGNQRQDKPKDPFLTGVRTAGRVANLRRHGKASFVDIFDD GEKLQLYLRVNELGDKYEYFFKVVDRGDIIGIQGDLFFTAKGELTLLVKDFAMLAKSLIEPPDWSTMSPEFRYSHRYVDF LYNDNARRFMETRFKIIREIRNILGEEGFIEVETPILQPVYGGALARPFKSHVNYLNEDWYLRISLELYLKRFIVGGFNK VFEIGKVFRNEDIDVTHNPEFTLMELYWAYADYNDIMDLTERLFKQLADRVLHSTKIPYKVGEKTVEINLESFRRVSMYD SLSEALGKNVEEMTDDQLKELMQRNGLVPRGSLYIRGLMIEKLFDKLVTPSLVQPTFVTDYPIETTPLCKPHRNKPGLVE RFELYIAGVEFANAYTELNDPILQDKLFREEQDMMKRGDQEAHPYDKDFINALSYGMPPTGGLGIGIDRLVMLFTNNQSI KEVIPFPMVSSKLIEE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 8e-81 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_001192224.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 4e-81 | 41 |
