Gene Information

Name : Msed_1241 (Msed_1241)
Accession : YP_001191325.1
Strain : Metallosphaera sedula DSM 5348
Genome accession: NC_009440
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1219394 - 1220740 bp
Length : 1347 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase

DNA sequence :
ATGCATAAGCTGGCCATAATCGGGTATGGGGCGGCCGGATTTGCTGCAATGATTAAGGCCAACGAGTTGGGAGTTAAACC
TGTTCTAATAGGGAAGGGGGAAATAGGAGGAACTTGCGTTAACGTAGGCTGTGTCCCTTCTAAGAGGATGTTATACATCG
CAGAAATCTACAAGAAAGCTAGGGAGGTCACGGGAAGCGAGGTATATCCGCCCTTCAGTTCCTTTCAGGAGAAAGATGGT
CTAGTTCAGGAGATGAGGAAGACGAAGTATGAAGACCTCCTCTCATACTATGACGTGGAACTGATTCAGGGCGAGGCCAG
GTTCATCTCTCCCCACGCGGTAAAGGTGAATGGCCAGGTAATTGAGGCCGAGAAATTCGTGATTGCAACTGGGTCATCTC
CCCTAATCCCAAGGATACCTGGCCTGGACAAGGTTGGGTTCTGGACCAACAGAGAGGCCCTGTCCCCGGACAGGAGAATT
GACTCCCTTGCAGTGATAGGTGGAAGGGCCCTGGCCCTCGAGTTCGCACAGATGTACTCTAGGATGAAGGTTGAGGTCGC
AATCCTTCAGAGGAGTCCCGTACTGATCCCAGACTGGGAGCCTGAGGCCTCAGTAGAGGCAAGGAGGATCATGGAAAATG
ACGGAGTTGCTGTAGTCACAGGTGTGAACGTCAAGGAGGTCAGGAAAGGGGCAGGAAAGATCGTGATAACGGACAAGGGC
GAAGTTGAGGCTGACGAGATACTCCTGGCCACGGGGAGGAAGCCCAACGTTGACCTAGGACTTGAGAATGCTGGTGTTCG
CCTAAATGAGAGGGGAGGAATTAAGGTGGACGACGAACTGAGGACTGACAACCCACACATATACGCGGCAGGGGACGTCT
TGGGAGGTAAAATGTTGGAGGCCCTAGCAGGTAGGCAAGGTTCAATTGCCACAGAGAACGCGTTAACAGGTTCGCACAAA
AGAGTGGACGAGAACGCGGTCCCTCAGGTCATCTTTACTCAGCCCAACCTTGCGAGGGTTGGTCTCACGGAGGCTGAAGC
TAGAGCTAAGGAAGGTGAAGTTGAGGCAAGGGTTCTTCCCATGAGCTCAGTGGCAAAGGCTGAGATCATCAACTCTAGAC
TGGGTTTCGTCAAGATGGTAACCATGAACGGGAGGATCGTTGGAGTTCATGCCGTCGGAGAGAACGTCGCGGAGATGATC
GGTGAAGCTGCTCTTGCGATAAGGTTTGGGGCCACGGTGCACGACCTCATAGATACAGTGCACATGTTTCCAACAATCGC
CGAATCCCTCAGGTTAGTTGCACTGGCATTTAGGTCTGACGTGAGTAGGTTAAGCTGTTGTGTGTGA

Protein sequence :
MHKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAREVTGSEVYPPFSSFQEKDG
LVQEMRKTKYEDLLSYYDVELIQGEARFISPHAVKVNGQVIEAEKFVIATGSSPLIPRIPGLDKVGFWTNREALSPDRRI
DSLAVIGGRALALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKGAGKIVITDKG
EVEADEILLATGRKPNVDLGLENAGVRLNERGGIKVDDELRTDNPHIYAAGDVLGGKMLEALAGRQGSIATENALTGSHK
RVDENAVPQVIFTQPNLARVGLTEAEARAKEGEVEARVLPMSSVAKAEIINSRLGFVKMVTMNGRIVGVHAVGENVAEMI
GEAALAIRFGATVHDLIDTVHMFPTIAESLRLVALAFRSDVSRLSCCV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 6e-75 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 4e-75 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msed_1241 YP_001191325.1 mercuric reductase BAC0651 Protein 3e-75 41