Gene Information

Name : murD (Pmen_0920)
Accession : YP_001186420.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1039216 - 1040562 bp
Length : 1347 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
GTGACCCTGATCGCTTCCGACCAGTTCCGCATCGTTGTCGGCCTCGGCAAGAGCGGCATGTCCCTGGTGCGCTTTTTCGC
GCAGCAGGGCGTGCGCTTCGCCGTGGCCGACACGCGCGCGAACCCGCCGGAGCTGGACACGCTCAAGCGTGACTACCCGC
AGGTGGAAGTGCGTTGCGGCGAGCTGGACGTGGAGTTCCTCTGCCGCGCCTCGGAGCTTTACGTGAGCCCGGGCCTGGCC
ATTTCCACGCCCGCCCTGGCCGCGGCCGCCGCGCGCGGGGTCAAGCTGTCCGGCGATATCGATCTGTTCGCCCGCCACGC
CAAGGCGCCGATCGTGGCCATCACCGGCTCCAACGCCAAGAGCACCGTTACCACCCTGGTCGGCGAAATGGCCGCTGCAG
CCGGCAAGCGCGTCGCCGTCGGCGGCAACCTCGGCACGCCGGCGCTGGATCTGCTGGCCGACGATGTCGAGCTGTACGTG
CTGGAGCTGTCCAGCTTCCAGCTGGAGACCACCGATCAGCTCAACGCCGAAGTGGCCACCTGCCTCAACATCAGCGAAGA
CCACATGGATCGCTACAGCGGTCTGCCGGCCTATCACCTGGCCAAGCACCGCATCTTCCGCGGCGCGCGTCAGGTGGTGG
TCAACCGCGACGACGCCCTGTCGCGTCCGCTGATCGCCGATCAGGTGACCTGCTGGGAATTCGGCCTGGGCAAACCGGAC
TTCAAACGCTTCGGTCTGCTCGAGGAAAACGGCGAGAAGTCCCTGGCGTTTCGCTTCGAAGCGCTGCTGCCGGTGAGCGA
GCTGAAGATCCGCGGCGCGCACAATCAGTCCAACGCCCTGGCGGCGTTGGCGCTCGGCCATGCCGTTGGCCTGCCGATGG
AAGCCATGCTCGCCACCCTGCGCCAGTTCGCCGGATTGCCGCATCGTTGCCAGTGGGTCGGCGAGCGCGCCGGGGTCAAT
TATTACGATGATTCCAAGGCCACCAACGTCGGTGCCGCGCTGGCGGCCATCGAAGGCCTCGGTGCCGATATCGCCGGCAA
GCTGGTGCTGATCGCCGGTGGCGACGGCAAAGGCGCCGACTTCTCCGCGCTGAAGGCGCCGGTGGCGCGATTCTGCCGCG
CCGTGGTGCTGCTCGGTCGCGATGCCGAGCTGATCGCCGCCGCTCTGGGCGATGCCGCGCCGCTGGTGCGGGTGACAACC
CTGGACGAAGCGGTGCAGCGCTGCAGCGAACTGGCAGAGGCTGGCGATGCCGTGCTGCTGTCGCCGGCCTGCGCCAGCCT
GGACATGTTCAAGAACTTCGAAGAGCGCGGGCGTCTGTTCGCCCAGGCCGTGGGAGGGCTCGTCTGA

Protein sequence :
MTLIASDQFRIVVGLGKSGMSLVRFFAQQGVRFAVADTRANPPELDTLKRDYPQVEVRCGELDVEFLCRASELYVSPGLA
ISTPALAAAAARGVKLSGDIDLFARHAKAPIVAITGSNAKSTVTTLVGEMAAAAGKRVAVGGNLGTPALDLLADDVELYV
LELSSFQLETTDQLNAEVATCLNISEDHMDRYSGLPAYHLAKHRIFRGARQVVVNRDDALSRPLIADQVTCWEFGLGKPD
FKRFGLLEENGEKSLAFRFEALLPVSELKIRGAHNQSNALAALALGHAVGLPMEAMLATLRQFAGLPHRCQWVGERAGVN
YYDDSKATNVGAALAAIEGLGADIAGKLVLIAGGDGKGADFSALKAPVARFCRAVVLLGRDAELIAAALGDAAPLVRVTT
LDEAVQRCSELAEAGDAVLLSPACASLDMFKNFEERGRLFAQAVGGLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-85 53
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-85 53