Gene Information

Name : Pmen_4225 (Pmen_4225)
Accession : YP_001189704.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4629853 - 4632057 bp
Length : 2205 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein

DNA sequence :
ATGAGCCGTTGCTGCGACCATTCGCACGAACCCGTTGCCGGGGGCGGGCAGCCCGTCGGGCATGAGCACCACGCTGCTCC
CCAGCTGCAGTCTGACGAGGCGCTGGGCGGTGCGTTCACCACGCGCATCCGCATCGAGCAGATGGACTGTCCGACCGAGG
AGCGGCTGCTCCGCGATGCCCTGGGCAAGCTGCCGGGCGTCGCCGCCCTGCATTTCAATCTGCTGCAGCGCGTGCTCACC
GTCGGCCATGACGAAGGCGCGCTGACGCGCGTGCTGTCGGCGATCCGGGCGCTGGGGTTCACCCCGCAGGTGGAAGGGCA
GGCTGGGGCGCCTGCGCCCGCCGTAGCGCCTGCGCACAAACCCTGGTGGCCGCTGGCGCTGGCCGGCGTGCTGGCCACGG
CCTCGGAGCTGGTGCATTTCGCGGCTCTCGGTCCCGACTGGCTGGTGGCGCTGCTCGCCGTGATGGCCATCGCCATCTGC
GGGCCGAGCACCTACAGAAAAGGCTGGGTCGCCCTGAAGAACCGCAACCTCAACATCAATGCGCTGATGAGCATCGCCGT
GACCGGCGCGGTGCTGACCGGCCAGTGGCCGGAAGCGGCGATGGTGATGGTGCTTTTCACCCTGGCCGAGCTGATCGAGG
CGCGTTCGCTGCAGCGGGCGCGCAACGCCATTGCCAGTCTGATGGACCTGGCACCGCCGCGCGCCACGCGGCGCCAGGCC
GATGGCAGCTGGCAGGAGGTGGACGTGCAGGCGGTGGCGGTCGGCGATGTGCTGCGGGTGCGGCCGGGCGAACGCATCGG
CCTGGATGGCGAGGTGATCGCCGGTGCCTCGACGGTCAACCAGGCGCCGATCACCGGTGAGAGCCTGCCGCTGGACAAGG
GCGTCGGTGACACGCTGTTCGCCGGCACCATCAACCAGGCGGGGTCGCTGGAATACCGGGTGACGGCGGCGGCGCGCGAC
ACCACGCTGGCGCGCATCATCCATGCGGTGGAGGAGGCGCAGGGCTCGCGCGCGCCGACCCAGCGCTTCGTCGATCGCTT
CTCGCGCATCTATACCCCCACGGTGTTCGCCTTCGCCCTGGCGGTCGCCGTGCTGCCGCCGCTGTTGGCGGGCGGCGCCT
GGCTCGACTGGATCTACCGCGCGCTGGTGCTGCTGGTGGTGGCCTGCCCCTGCGCGCTGGTGATTTCCACGCCGGTGACC
ATCGTCAGCGGCCTGGCCGCGGCGGCGCGCAAGGGCATCCTGATCAAGGGCGGCGTGTACCTGGAAAGCGGTCGACACCT
GGCGCTGCTGGCGCTGGACAAGACCGGCACCCTGACCCATGGCAAACCGGTGCAGACCGACTGCCTGAGCCTGGGCGATG
GCGATACGCAGCAGCTCGCGCTGTGGGCTGCCAGCCTGGCGGCGCGTTCCGATCACCCGGTTTCCCAGGCGCTGGCCCGT
GCCCTGGAGGGCCAGGCGCTGGCTGAAGTGGAGGCGTTCGAGGCGTTGCCGGGGCGCGGCACCCGCGGCCGTATCGACGG
GCGCCTGCTGCACCTGGGCAATCACCGCCTGGTCGAGGAACTCGGGCTGTGCTCGCCGGCACTGGAGCAGCGCCTGGAGG
CGTTGGAGCGGCAGGGCAAGAGTGTGGTGCTGCTGTGCGACGAGCAGCGTGCGCTGATGCTCTTCGCCGTGGCCGACACG
CTACGCCAGAGCAGCCGCGAGGCGGTGCAGCAGTTGCACGCGCTGGGCGTGCGCACCTGCATGCTCAGCGGCGACAACGC
CCACACCGTGGCGGCCATCGCCGAACAGGTCGGCATCGACGAGGCGCGCGGCGACCTGCTGCCGGCGGACAAGCTGGCCT
GGGTCGAGACGCGTCAGGCACAGGGGCGGGTGGTCGGCATGGTCGGCGATGGCATCAACGACGCACCGGCGCTGGCCAAG
GCGCAGATCGGCTTCGCCATGGGCGCTGCCGGCACCGACACGGCCATCGAGACGGCGGATGTTGCGCTGATGGATGACGA
CCTGCGCAAGATCCCCGCCTTCGTCCGCCTGTCCCGCCAGACCCACGCCATTCTCGTGCAGAACATCGTGCTGGCGCTGG
GCATCAAGGCGATCTTCCTGGCCCTGACCCTGGCTGGCGAGGCGACAATGTGGATGGCCGTGTTCGCCGACATGGGCGTG
AGCCTTCTGGTGGTGTTCAACGGCCTGCGCCTGCTGCGCAAGTGA

Protein sequence :
MSRCCDHSHEPVAGGGQPVGHEHHAAPQLQSDEALGGAFTTRIRIEQMDCPTEERLLRDALGKLPGVAALHFNLLQRVLT
VGHDEGALTRVLSAIRALGFTPQVEGQAGAPAPAVAPAHKPWWPLALAGVLATASELVHFAALGPDWLVALLAVMAIAIC
GPSTYRKGWVALKNRNLNINALMSIAVTGAVLTGQWPEAAMVMVLFTLAELIEARSLQRARNAIASLMDLAPPRATRRQA
DGSWQEVDVQAVAVGDVLRVRPGERIGLDGEVIAGASTVNQAPITGESLPLDKGVGDTLFAGTINQAGSLEYRVTAAARD
TTLARIIHAVEEAQGSRAPTQRFVDRFSRIYTPTVFAFALAVAVLPPLLAGGAWLDWIYRALVLLVVACPCALVISTPVT
IVSGLAAAARKGILIKGGVYLESGRHLALLALDKTGTLTHGKPVQTDCLSLGDGDTQQLALWAASLAARSDHPVSQALAR
ALEGQALAEVEAFEALPGRGTRGRIDGRLLHLGNHRLVEELGLCSPALEQRLEALERQGKSVVLLCDEQRALMLFAVADT
LRQSSREAVQQLHALGVRTCMLSGDNAHTVAAIAEQVGIDEARGDLLPADKLAWVETRQAQGRVVGMVGDGINDAPALAK
AQIGFAMGAAGTDTAIETADVALMDDDLRKIPAFVRLSRQTHAILVQNIVLALGIKAIFLALTLAGEATMWMAVFADMGV
SLLVVFNGLRLLRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 68
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-109 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-109 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-108 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pmen_4225 YP_001189704.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 68
Pmen_4225 YP_001189704.1 heavy metal translocating P-type ATPase BAC0461 Protein 2e-72 42