Gene Information

Name : leuS (Pmen_3786)
Accession : YP_001189266.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4173445 - 4176165 bp
Length : 2721 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCCGCGACAAACGGCGTGCGCGCCGCAATCTGGGTTTCCCTCGGCAGACGGCGCTCATGTATGCTACGACGTTTTCCG
CAAGCCCCATTCCTTCAGCGCCAGAGCCATGCACGAACAGTACTCGCCCCGTGAAATAGAAGCCGCCGCGCAGTCCCACT
GGGACGCGCAGAAATCCTTCGTCGTCAGCGAACAGCCCGGCAAGGACACCTTCTACTGCCTGTCGATGTTCCCCTACCCC
AGCGGCAAGCTACACATGGGGCACGTGCGCAACTACACCATCGGTGACGTGATTGCGCGCTACCAGCGCATGCAGGGCAA
GAACGTGCTGCAGCCGATGGGCTGGGACGCCTTCGGCATGCCGGCGGAAAACGCCGCGATGAAGAACCAGGTGGCGCCGG
CCAAGTGGACTTACGAGAACATCGCCTACATGAAGTCCCAGCTCAAGTCGCTGGGCCTGGCCATCGACTGGACGCGCGAA
GTCACCACCTGCAAGCCGGACTATTACCGCTGGGAACAGTGGCTGTTCACCCGCCTGTTCGAAAAGGGCGTGATCTACCG
CAAGAACGGTACCGTCAACTGGGACCCGGTGGACCAGACCGTACTGGCCAACGAGCAGGTCATCGACGGCCGCGGCTGGC
GTTCGGGTGCGCTGATCGAGAAGCGCGAAATCCCGATGTACTACTTCAAGATCACCGCTTACGCCGATGAGCTGCTGAGC
AGCCTGGACGAGCTGGATGGCTGGCCCGAGCAGGTCAAGACCATGCAGCGCAACTGGATCGGCAAGAGCTTCGGTGCCGA
CATCGTGTTCGACTACGACGTCGCCAGCATCGGCATCGATGGTCAGCTGAAGGTCTACTCCACTCGCCCCGACACCCTGA
TGGGCGCCACCTACGTCGCCGTGGCCGCCGAACACCCGCTGGCCCAGCGCGCTGCCGAATCCAATCCGGCCATCGCTGCC
TTTATCGCCGAGTGCAAGGCCGGCTCCGTGGCCGAGGCCGACATGGCCACCATGGAGAAGAAAGGCCTGGCCACCGGCCA
GTTCGTCATTCATCCGCTGACCGGCGACAAGCTGCCGGTATTCGTCGCCAACTATGTGCTGTGGGGCTACGGCGAAGGCG
CGGTGATGGCCGTGCCGGCGCATGACGAGCGCGACTTCGAGTTCGCCAACAAGTACGACCTGCCGATCAAGCAGGTCTAC
ACCGGCGAAGGCAAGGACTACGACGCCAGCACCTGGCAGGACTGGTACGGCGACAAGGCCGGCCTGACCACCATCAACTC
CGGCAAGTACGACGGTCTGGACTTCAGCGCCGCCTTCGACGCCATCGTCGGCGACCTGGAAGCCAGCGCGCATGGCGCGC
GCAAGACCCAGTTCCGCCTGCGCGACTGGGGCATCAGCCGCCAGCGCTACTGGGGCTGCCCGATCCCGATCATCCACTGC
GACAGCTGCGGCGATGTACCGGTGCCGGAAGACCAGTTGCCGGTGGTGCTGCCCGAAGACGTGGTGCCGGATGGCGCAGG
CAGCCCGCTGGCGAAGATGCCCGAGTTCTACGAGTGCACCTGCCCGAAATGCGGCGCCCCGGCCAAGCGTGAAACCGACA
CCATGGACACCTTCGTGGAGTCGTCCTGGTACTTCGCCCGCTACGCCAGCCCGAACTACGAAGGCGGCATGGTCGACCCG
CAAGCGGCCAACCACTGGTTGCCGGTGGATCAGTACATCGGCGGCATCGAGCACGCCATCCTCCACCTGCTCTACGCGCG
CTTCTTCCACAAGCTGATGCGCGACGAAGGTCTGGTGTCTTCGAATGAGCCGTTCAAGAACCTGCTGACCCAGGGCATGG
TGGTCGCCGAGACCTATTACCGCACCCTGGAAAACGGCGGCAAGGACTGGTTCAACCCGGCCGATGTCGAGGTCGAGCGT
GACGCCAAGGCCAAGGTCATCGGCGCCAAGCTCAAAAGCGACGGCCTGCCGGTGGAAATCGGCGGCACCGAGAAAATGTC
CAAGTCGAAGAACAACGGCGTGGACCCGCAGGACATGATCGATGCGTACGGCGCCGACACCTGCCGTCTGTTCATGATGT
TCGCCTCGCCGCCCGACATGAGCTGCGAATGGTCGGATGCCGGCGTCGAGGGTGCCAACCGCTTCCTGCGTCGCGTCTGG
CGTCTGGCTCACGGCCATGTCAGCGCCGGTCTGCCGGGCAAGCTGGATGTCGCCAGCCTCAGCGACGAGCAGAAAGCCGT
GCGCCGCGCCATTCACCTGGCGATCAAGCAGGCCAGCAACGATATCGGCCAGCACCACAAGTTCAACACCGCCATCGCCC
AGGTGATGACGCTGATGAACGTGCTGGAAAAGGCCGCCACCGCGACCGAACAGGACCGCGCGCTGGTACAGGAAGGCCTG
GAGATCGTCACCCTGCTGCTGGCACCGATCACCCCACACATCAGCCACGAGCTGTGGCAGCGCCTGGGTCATGCCGATGC
GGTGATCGACGCACAGTGGCCGCAGGTCGACGAATCCGCCCTGGTGCAGGACAGCCTGACCCTGGTGGTACAGGTCAACG
GCAAGCTGCGCGGGCAGATCGAAGTTCCGGCCAGCGCCTCCCGCGAGGACGTCGAAGCCGCCGCCCGCGCCAACGAGAAC
GTGCTGCGCTTTACCGAGGGCCTGAGCATTCGCAAGGTCATCGTGGTGCCAGGCAAGCTGGTCAACATAGTCGCCAACTG
A

Protein sequence :
MPRQTACAPQSGFPSADGAHVCYDVFRKPHSFSARAMHEQYSPREIEAAAQSHWDAQKSFVVSEQPGKDTFYCLSMFPYP
SGKLHMGHVRNYTIGDVIARYQRMQGKNVLQPMGWDAFGMPAENAAMKNQVAPAKWTYENIAYMKSQLKSLGLAIDWTRE
VTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYADELLS
SLDELDGWPEQVKTMQRNWIGKSFGADIVFDYDVASIGIDGQLKVYSTRPDTLMGATYVAVAAEHPLAQRAAESNPAIAA
FIAECKAGSVAEADMATMEKKGLATGQFVIHPLTGDKLPVFVANYVLWGYGEGAVMAVPAHDERDFEFANKYDLPIKQVY
TGEGKDYDASTWQDWYGDKAGLTTINSGKYDGLDFSAAFDAIVGDLEASAHGARKTQFRLRDWGISRQRYWGCPIPIIHC
DSCGDVPVPEDQLPVVLPEDVVPDGAGSPLAKMPEFYECTCPKCGAPAKRETDTMDTFVESSWYFARYASPNYEGGMVDP
QAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRTLENGGKDWFNPADVEVER
DAKAKVIGAKLKSDGLPVEIGGTEKMSKSKNNGVDPQDMIDAYGADTCRLFMMFASPPDMSCEWSDAGVEGANRFLRRVW
RLAHGHVSAGLPGKLDVASLSDEQKAVRRAIHLAIKQASNDIGQHHKFNTAIAQVMTLMNVLEKAATATEQDRALVQEGL
EIVTLLLAPITPHISHELWQRLGHADAVIDAQWPQVDESALVQDSLTLVVQVNGKLRGQIEVPASASREDVEAAARANEN
VLRFTEGLSIRKVIVVPGKLVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-142 42