Gene Information

Name : guaA (Pmen_3485)
Accession : YP_001188965.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3844964 - 3846541 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCACGACATTCACGCCCACCGCATCCTCATTCTGGACTTCGGTTCCCAGTACACCCAACTGATCGCCCGCCGTGT
ACGCGAGATCGGCGTCTATTGCGAACTGCACCCCTGGGACATGAGCGACGAGGACATCCGCGCCTTCGCTCCGCGCGGCA
TCATCCTCGCCGGCGGCCCGGAGTCGGTGCATGAAGCCAATAGCCCGCGCGCGCCGCAAGCGGTGTTCGACCTGAACGTC
CCGGTGCTGGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGCTCGGCGGCAAGGTGGAAGGCTCCGACCTGCGCGA
GTTCGGCTATGCCCGTGTCGACGTGGTCGGCAAGAGCCAGCTGCTGGCCGGTATCGAAGACCATGTCGACGCCGATGGCG
TATTCGGCCTCGACGTGTGGATGAGCCACGGCGACAAGGTCACCCGCCTGCCGGAGGGCTTCCACATCCTCGCCAGCACC
CCGAGCTGCCCGATCGCCGCCATGAGCGACGACACCCGCCACTACTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CAAGCAGGGCGGCCGCATTCTGTCCCGCTTCGTGCTGGAGATCAGCGGCTGCGAGGCTCTGTGGACCCCGGCCAACATCG
TCGAAGACGCCGTGGCCGCCGTGCGTGCCCAGGTCGGCGACGCCAACGTGCTGCTCGGCCTGTCCGGCGGTGTCGACTCT
TCCGTGGTCGCGGCGCTGCTGCACAAGGCCATCGGCGATCAGCTCACCTGCGTGTTCGTCGACAACGGCCTGCTGCGTCT
GCACGAGGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTGAAGGTGATCCGTGCCAATGCCGAGGAGCAGT
TCCTCTCCAACCTGGCCGGCGAGTCCGACCCGGAGAAGAAGCGCAAGATCATCGGCCGTACCTTCATCGACGTGTTCGAT
GCCGAGGCCAGCAAGCTGGACAACATCCAGTTCCTCGCCCAGGGCACCATCTACCCGGACGTGATCGAGTCGGCCGGCGC
CAAGAGCGGCAAGGCCCACGTGATCAAGAGCCACCACAACGTCGGTGGCCTGCCCGAGGAAATGAACCTCAAGCTGGTCG
AGCCGCTGCGTGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAACTGGGCCTGCCCTACGACATGGTCTACCGC
CACCCGTTCCCGGGCCCGGGCCTGGGCGTGCGTATCCTCGGCGAAGTGAAGAAGGAATACGCCGACCTGCTGCGCCGTGC
CGACCATATCTTCATCGAAGAGCTGCGCAAGGCCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCGG
TGAAATCGGTCGGCGTGGTAGGTGATGGCCGCCGCTACGCCTGGGTCGTCGCCCTGCGCGCCGTGGAAACCGTGGACTTC
ATGACCGCACGCTGGGCGCACCTGCCCTACGAGCTGCTGGAAACCGTCAGCGGCCGCATCATCAACGAGATCGAAGGCAT
CTCCCGCGTCACCTACGACGTGTCGAGCAAGCCGCCCGCGACCATCGAGTGGGAGTGA

Protein sequence :
MAHDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPWDMSDEDIRAFAPRGIILAGGPESVHEANSPRAPQAVFDLNV
PVLGICYGMQTMAEQLGGKVEGSDLREFGYARVDVVGKSQLLAGIEDHVDADGVFGLDVWMSHGDKVTRLPEGFHILAST
PSCPIAAMSDDTRHYYGVQFHPEVTHTKQGGRILSRFVLEISGCEALWTPANIVEDAVAAVRAQVGDANVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEEQFLSNLAGESDPEKKRKIIGRTFIDVFD
AEASKLDNIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADLLRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDF
MTARWAHLPYELLETVSGRIINEIEGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-129 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-129 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-129 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-115 49