Gene Information

Name : hemC (Pmen_0280)
Accession : YP_001185786.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 288636 - 289574 bp
Length : 939 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCCCCGCGAAATCCGCATCGCCACCCGTAAGAGCGCCCTGGCCCTGTGGCAGGCCGAATATGTCAAAGCCCGCCTCGA
ACAGGCCCACCCCGGTCTGCTGGTGAGTCTGGTGCCCATGGTCAGCCGCGGCGACAAGCTGCTCGATGCGCCGCTGGCGA
AGATCGGCGGCAAGGGCCTGTTCGTCAAGGAACTGGAAACCGCGCTGCTGGAGAACGAGGCCGACATCGCCGTGCATTCG
ATGAAGGACGTGCCGATGGACTTCCCCGAAGGCCTGGGCCTGTACTGCATCTGCGAGCGCGAGGACCCGCGCGACGCCTT
CGTTTCCAACACCTATGACAGCCTCGACGCCTTGCCGGCCGGCAGCGTGGTGGGCACCTCCAGCCTGCGTCGCCAGGCCC
AGCTGCTGGCCCGCCGGCCCGATCTGAAAATCCAGTTCCTGCGCGGCAACGTCAACACCCGCCTGGCCAAGCTCGATGCC
GGCGAGTACGACGCCATCATCCTTGCCGCCGCCGGCCTGATCCGCCTCGGCTTCCAGGACCGTATCCGCAGCTCGATCAG
CGCCGAGGACAGCCTGCCGGCCGGTGGCCAGGGTGCCGTCGGCATCGAGTGCCGAAGCGCCGACGCCGAGATCCATGCGC
TGCTGGCGCCGCTGCATCACCGCGAAACCGCGCTGCGGGTGACCGCCGAGCGCGCATTGAACAAGCGCCTCAATGGCGGC
TGCCAGGTGCCCATCGCCTGCTACGCGCTGCTGGAGAACGACCAACTGTGGCTGCGCGGCCTGGTCGGCCAGCCTGACGG
CGGCCTGTTGCTGCGCGCAGAACACCGCGCCGCCAGCAGCGACGCCGAAGCCCTGGGGGTGCGGGTGGCCGAGGCGCTGC
TGGCGCAGGGCGCCGAGGCCATCCTCAAGGCCGTTTATGGCGAGGCCGGCCACCCGTGA

Protein sequence :
MPREIRIATRKSALALWQAEYVKARLEQAHPGLLVSLVPMVSRGDKLLDAPLAKIGGKGLFVKELETALLENEADIAVHS
MKDVPMDFPEGLGLYCICEREDPRDAFVSNTYDSLDALPAGSVVGTSSLRRQAQLLARRPDLKIQFLRGNVNTRLAKLDA
GEYDAIILAAAGLIRLGFQDRIRSSISAEDSLPAGGQGAVGIECRSADAEIHALLAPLHHRETALRVTAERALNKRLNGG
CQVPIACYALLENDQLWLRGLVGQPDGGLLLRAEHRAASSDAEALGVRVAEALLAQGAEAILKAVYGEAGHP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-72 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-72 61