Gene Information

Name : Pmen_2068 (Pmen_2068)
Accession : YP_001187561.1
Strain : Pseudomonas mendocina ymp
Genome accession: NC_009439
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 2289642 - 2291885 bp
Length : 2244 bp
Strand : +
Note : PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein

DNA sequence :
ATGTATAAAGATCTAAAATTCCCCGTCCTCATCGTTCACCGCGACATCAAGGCCGACACGGTGGCCGGCGATCGCGTGCG
CGCCATCGCGCGCGAGCTGGAACAGGACGGTTTCAGCATTCTCCCCACCGCCAGTGCAGCCGAGGGCCGCATCGTCGCCT
CCACCCACCACGGTCTGGCCTGCATCCTGGTGGCCGCCGAGGGCGCGGGCGAGAACAGTCGTCTGCTGCAGGACATGGTC
GAGCTGATCCGCGTGGCGCGGGTGCGTGCTCCGCAATTGCCGATCTTCGCCCTCGGCGAGCAGGTCACCATCGAGAATGC
GCCGGCCGAGGCCATGGCCGATCTCAATCACCTGCGCGGCATCCTCTACCTCTACGAAGACACCGTTTCCTTCCTGGCCC
GTCAGGTGGCGCGGGCGGCGCACAACTACCTCGACGGCCTGCTGCCGCCGTTCTTCAAGGCGCTGGTGCAGCACACCGCA
CAATCCAACTATTCTTGGCACACGCCCGGTCACGGCGGCGGCGTGGCTTACCGCAAGAGTCCGGTAGGCCAGGCGTTTCA
CCAGTTCTTCGGGGAAAACACCCTGCGTTCGGATCTGTCGGTGTCGGTGCCGGAGCTGGGGTCGCTGCTCGATCACACAG
GTCCGCTCGCCGAAGCCGAGGCGCGCGCCGCGCGCAACTTCGGCGCCGACCACACCTTCTTCGTGATCAACGGCACGTCC
ACGGCGAACAAGATCGTCTGGCATTCGATGGTCGGGCGTGACGATCTGGTACTGGTGGACCGCAACTGCCACAAGTCGAT
CCTGCATTCGATCATCATGACCGGCGCGATCCCGCTGTACCTGTGCCCCGAGCGCAACGAGCTGGGCATCATCGGGCCGA
TTCCGCTGTCGGAGTTCAGCCGTGAATCGATCCAGGCCAAGATCGACGCCAGCCCGCTGGCACGTGGTCGCGCGCCCAAG
GTCAAGCTGGCGGTGGTGACCAACTCCACCTACGACGGGCTTTGCTACAACGCCGAGATGGTCAAGCAGGCGCTGGGCGA
TTCGGTCGAGGTGCTGCACTTCGACGAGGCCTGGTACGCCTACGCCGCGTTCCATGAGTTCTATGCCGGCCGCTACGGCA
TGGGCACCCAGTGCGACGAGCGCTCGCCGCTGGTGTTCACCACCCATTCCACGCACAAGCTGCTGGCCGCGTTCAGCCAG
GCCTCGATGATCCATGTGCAGGATGGCGGGCAGCGCCAATTGGACCGTGACCGCTTCAACGAAGCCTTCATGATGCACAT
CTCCACGTCGCCGCAGTACGGCATCATCGCCTCGCTGGATGTGGCCTCGGCGATGATGGAAGGCCCGGCCGGGCGTTCGC
TGATCCAGGAAACCTTCGACGAGGCCCTGAGCTTCCGTCGTGCCCTGGCCAACGTGCGCCGCAACCTCGATGCCGAGGAC
TGGTGGTTCAGCATCTGGCAGCCGGGCGAGGCCGACGGCGCCGACAGCCTGTCGACTGCCGACTGGGTGCTGCAGCCGGA
CGCCGACTGGCACGGTTTCGGCGAGGTAGCCAATGACTATGTGCTGCTTGACCCGATCAAGGTGACGCTGGTGATGCCCG
GTCTCAACGCGGCCGGCAAGCTGCAGGAGCGTGGGATCCCGGCGGCGGTGGTCAGCAAGTTCCTCTGGGAGCGCGGCCTG
GTCGTGGAAAAGACCGGTCTGTATTCCTTCCTGGTGCTGTTTTCCATGGGCATCACCAAGGGCAAGTGGAGCACGCTGCT
GACCGAACTGCTGGAATTCAAGCGCAGCTACGACGCCAATCTGCCGCTGGTGGACGTGCTGCCCTCCATCGCTCATGCGG
GTGGCGGCTGCTATCAGGGCATGGGGCTGCGCGATCTGTGTGATGCGCTGCATGGCTGCTACCGCGACAACGCCACGGCC
AAGGCGTTGAAGAGCATGTACACGGCTTTGCCGGAAGTGGCGATCAAGCCGGCCGAGGCTTACGACCGCCTGGTGCGCGG
CGAGGTCGAGGCGGTGCCGATCGATCAGCTGCAGGGGCGCATCGCTGCCGTGATGCTGGTGCCTTATCCGCCGGGCATTC
CGCTGATCATGCCGGGTGAGCGCTTCACCGCCGCGACCCGCTCGATACTCGATTACCTGGCCTTCGCGCGGACCTTCGAT
CAGGCCTTCCCGGGCTTCGACATCGACGTGCACGGCCTGCAGACCGAGGCGGGGCAGTATTGCGTCGATTGTCTCGTGGA
GTGA

Protein sequence :
MYKDLKFPVLIVHRDIKADTVAGDRVRAIARELEQDGFSILPTASAAEGRIVASTHHGLACILVAAEGAGENSRLLQDMV
ELIRVARVRAPQLPIFALGEQVTIENAPAEAMADLNHLRGILYLYEDTVSFLARQVARAAHNYLDGLLPPFFKALVQHTA
QSNYSWHTPGHGGGVAYRKSPVGQAFHQFFGENTLRSDLSVSVPELGSLLDHTGPLAEAEARAARNFGADHTFFVINGTS
TANKIVWHSMVGRDDLVLVDRNCHKSILHSIIMTGAIPLYLCPERNELGIIGPIPLSEFSRESIQAKIDASPLARGRAPK
VKLAVVTNSTYDGLCYNAEMVKQALGDSVEVLHFDEAWYAYAAFHEFYAGRYGMGTQCDERSPLVFTTHSTHKLLAAFSQ
ASMIHVQDGGQRQLDRDRFNEAFMMHISTSPQYGIIASLDVASAMMEGPAGRSLIQETFDEALSFRRALANVRRNLDAED
WWFSIWQPGEADGADSLSTADWVLQPDADWHGFGEVANDYVLLDPIKVTLVMPGLNAAGKLQERGIPAAVVSKFLWERGL
VVEKTGLYSFLVLFSMGITKGKWSTLLTELLEFKRSYDANLPLVDVLPSIAHAGGGCYQGMGLRDLCDALHGCYRDNATA
KALKSMYTALPEVAIKPAEAYDRLVRGEVEAVPIDQLQGRIAAVMLVPYPPGIPLIMPGERFTAATRSILDYLAFARTFD
QAFPGFDIDVHGLQTEAGQYCVDCLVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 1e-131 44
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 8e-128 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pmen_2068 YP_001187561.1 lysine decarboxylase VFG1670 Protein 7e-132 44