Gene Information

Name : Csac_2467 (Csac_2467)
Accession : YP_001181235.1
Strain : Caldicellulosiruptor saccharolyticus DSM 8903
Genome accession: NC_009437
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2614481 - 2616193 bp
Length : 1713 bp
Strand : -
Note : TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGGCATACCATATCAAAAGAGAGGATTATGTCAAAATATACGGACCTACAGTTGGTGATAAAATACGACTTGCAGATAC
TGATTTAATAATTGAAATTGAAAAAGATTATACAGTCTATGGAGAAGAATGTAAATTTGGTGCTGGAAAAAATATTAGAG
ATGGAATGAGCCAAAATCAGTTTGCTTGCAATAATAGTGCTTTAGATATTGTAATAACAAATGTTGTGATAATAGATTGG
TGGGGAATTGTAAAAGGAGATATAGGAATTAAAGATGGTAAGATAGTCGGAATTGGAAAAGCGGGGAATCCAAATGTCAT
GGATGGAGTTACTCCTAATATGGTGATAGGTCCTTCAACTGATGTTATTTCGGGTGAAGGCTTGATTGCTACAGCAGGTG
CAATTGACACTCATGTTCATTTCATTTGTCCTCAGCAAATAGAGACTGCTCTTTATAAAGGGATAACGACATTAATAGGT
GGCGGGATAGGACCTACTGAAGGAACTAAAGCTACAACTTGTACTCCAGGAGCTTGGAATATATTCAAAATGTTAAAAGC
AGTAGATAATTTTCCTGTGAATATTGGGCTGACAGGGAAGGGGAATTCCTCATATGAAAAGCCGTTAATTGAACAAGTGA
AAGCAGGGGTAGTAGGTTTTAAAATACATGAAGACTGGGGTGCAACACCAACAGTTATAGATACATGTTTGAAAGTAGCT
GATGAGTTTGACGTCCAAGTAGCTTTGCACACTGATAGTATGAATGAAGCGGGATTTGTTGAGGATACAATAAAAGCTAT
TGGCAATAGAGTTTTACATGCATATCATGTTGAAGGTGCAGGTGGTGGCCATGCACCAGACGTTCTGAAAGTTGTACAGT
ATAAAAATATAATACCTTCATCTACCACTCCTACAATGCCGCATACAATAAATACTTTTTCAGAACATCTTGATATGCTG
ATATTCTGTCATCATCTTGATAAGAATTTAGAAGAAGATGTTGAATTTGCAAAAGCAAGAATAAGAGAAACAACCATGGC
AGCAGAGGACTACTTACATGATATAGGAGCAATAAGCATTATAAATTCTGATTCACAAGCTATGGGAAGAATAGGAGAGG
TAATTACTCGAACATGGCAAACAGCTGACAAAATGAAAAAGATATACGGACGTCTACCAGAAGATACCCAAAATGATAAT
TATCGTGTAAAGAGATATATAAGTAAGTATACGATTAATCCAGCAATTGCTCATGGTATTTCACAATATATTGGTTCTCT
TGAACCAGGAAAAATTGCAGATATAGTTTTGTGGAAACCTGCATTCTTCGGAGTAAAGCCAGAGATGATAATAAAAGGAG
GATTTATTATAGCATCAAAAATGGGTGATGCTAATGCTTCAATACCAACCCCTCAACCTGTTATTATGAAAAAAATGTTT
GGAGCATTTGGAAAAGCTGTTTATGATACTGCTGTTACATTTGTTTCTGGTTATTTCTATGAAAATGAGATAAATAAGAA
AATAGGAATAAACAAAAAAGTCTTGCCAGTGAAAAATTGTAGAAATATATCAAAGGAAAATATGATATATAATAACCAAC
TGCCGAAGATAGAAATTGATTATAAGACATTTGAAGTATTTGTCAATGGCAACAAGATTAATGTTCCTCCTGCAGTTTCC
TTAAACATGACACGAAGATATAACCTATTTTAA

Protein sequence :
MAYHIKREDYVKIYGPTVGDKIRLADTDLIIEIEKDYTVYGEECKFGAGKNIRDGMSQNQFACNNSALDIVITNVVIIDW
WGIVKGDIGIKDGKIVGIGKAGNPNVMDGVTPNMVIGPSTDVISGEGLIATAGAIDTHVHFICPQQIETALYKGITTLIG
GGIGPTEGTKATTCTPGAWNIFKMLKAVDNFPVNIGLTGKGNSSYEKPLIEQVKAGVVGFKIHEDWGATPTVIDTCLKVA
DEFDVQVALHTDSMNEAGFVEDTIKAIGNRVLHAYHVEGAGGGHAPDVLKVVQYKNIIPSSTTPTMPHTINTFSEHLDML
IFCHHLDKNLEEDVEFAKARIRETTMAAEDYLHDIGAISIINSDSQAMGRIGEVITRTWQTADKMKKIYGRLPEDTQNDN
YRVKRYISKYTINPAIAHGISQYIGSLEPGKIADIVLWKPAFFGVKPEMIIKGGFIIASKMGDANASIPTPQPVIMKKMF
GAFGKAVYDTAVTFVSGYFYENEINKKIGINKKVLPVKNCRNISKENMIYNNQLPKIEIDYKTFEVFVNGNKINVPPAVS
LNMTRRYNLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-139 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-139 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-131 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-133 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 5e-133 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-133 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Csac_2467 YP_001181235.1 urease subunit alpha VFG0270 Protein 1e-148 60