Gene Information

Name : Csac_1466 (Csac_1466)
Accession : YP_001180257.1
Strain : Caldicellulosiruptor saccharolyticus DSM 8903
Genome accession: NC_009437
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 1627773 - 1629119 bp
Length : 1347 bp
Strand : +
Note : TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein

DNA sequence :
ATGGAACCTGATATTCTCCAAAGCCACAGTGAAATGCCAGAAAGCCGCGAGGCAGAAGAGGCTGTTGTTGGGGCGATGCT
TCTTGACAAAGAGGTAATTTCTGACATCACAGAGATTTTGACAGAAGATGATTTTGCAACCCCACAGCTAAAAGAAGTTT
TTGCAGCTATCATGGACCTTTTTGAAGAGGGCAAGCCCATAGATGTTATAACAGTTTCAGAACGTCTAAGAGAAAGAGGA
AGTTTTGAGGCGGTTGGTGGAAGTGAATATTTGACAAATCTTGTTATAAACACGCCAACATCTGCAAATGCTACATATTA
TGCAAGGATTGTTGAGGAAAAGTCGCTACTTAGAAAGCTTATAAACTCATCAATGAAGATAATAGAAAAGTGTAAAAGCC
AGACAGAAAGAGTTGAAGATATAGTTGATTTTGCTGAAAAGACTATCTTCAATGTGATTTCTCACAAAAGCTCAAGAGAT
TTTTCTCATTTAAAAGAAATATTAATTGAAACATACAATAAGATAGAGGAACTGTATCTCAGAAAATCACATATCATAGG
TGTGCCAACAGGATTTGCTGAATTTGACAGAATGACAGCAGGGCTTCAGCCATCAGATCTGATTTTGATTGCTGCAAGGC
CTGCAATGGGCAAGACAAGCTTTGCACTTAACATTGTCCAGCATGCAGCCTTAAGGGCAGGTGTTCCTGTTGCTATATTT
TCGCTTGAGATGTCAAAAGAACAGCTTGTAACCCGTATGATTTGCTCAGAAGCAATGATAGACAGTCACAAACTTCGTAC
TGGCAACTTAGAGGATGAAGAGTGGAAAAAGTTTGCAAAGGCTTTGGCACTTTTGTCAAATGCTCCAATTTATATTGACG
ACACACCTGCCATAACAGTTTCTGAGATGAGGGCAAAGTGTAGAAGGCTCAAACTCAAAGAAAAAGGTCTTGGTCTTGTG
ATGGTTGACTATTTGCAGCTTATGACAGCTCGTGGCAGATTTGAAAGCAAACAACAAGAAATTGCTGAGATTTCAAGGTC
ATTAAAAGCTTTGGCAAGAGAGCTAAATGTCCCTGTGCTTGCTCTTTCACAGCTATCCCGTGCACCTGAAACAAGGGCTG
ACCACAGACCGATACTCTCTGACCTTCGTGAAAGTGGTGCAATTGAGCAAGATGCGGATATTGTTGCGTTTTTGTACAGG
GACGAGTATTACAATCCTGACACTGACAAAAAACACATAGCAGAACTTATAATTGCAAAGCACAGAAATGGTCCGACTGG
AACAATTGAGCTTTTGTTCTTGGACAAGCATACAAAGTTCAAGGACTTAGAGAAAAACAGAGTATAA

Protein sequence :
MEPDILQSHSEMPESREAEEAVVGAMLLDKEVISDITEILTEDDFATPQLKEVFAAIMDLFEEGKPIDVITVSERLRERG
SFEAVGGSEYLTNLVINTPTSANATYYARIVEEKSLLRKLINSSMKIIEKCKSQTERVEDIVDFAEKTIFNVISHKSSRD
FSHLKEILIETYNKIEELYLRKSHIIGVPTGFAEFDRMTAGLQPSDLILIAARPAMGKTSFALNIVQHAALRAGVPVAIF
SLEMSKEQLVTRMICSEAMIDSHKLRTGNLEDEEWKKFAKALALLSNAPIYIDDTPAITVSEMRAKCRRLKLKEKGLGLV
MVDYLQLMTARGRFESKQQEIAEISRSLKALARELNVPVLALSQLSRAPETRADHRPILSDLRESGAIEQDADIVAFLYR
DEYYNPDTDKKHIAELIIAKHRNGPTGTIELLFLDKHTKFKDLEKNRV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 3e-69 44
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 8e-70 43
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 4e-70 41
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 7e-67 41
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-66 41