Gene Information

Name : murD (Ent638_0634)
Accession : YP_001175372.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 717966 - 719282 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCAGATTACCAGGGCAAAAAAGTCGTTATCATCGGGTTAGGCCTGACGGGTCTTTCCTGCGTGGACTTTTTCCTCGG
ACGGGGCGTGACGCCGCGTGTGATGGATACGCGTGTTTCACCGCCGGGTCTGGATAAACTTCCGGAAGAGGTGGAACGCC
ACCTTGGTGGTCTGAACGATGATTGGCTGCTGGCCGCCGATTTAATTGTGGCAAGCCCAGGGTTTGCTCTGGCGCACCCT
TCGTTAAGCGCTGCGGCTGATGCGGGCGTTGAGATTGTTGGCGATATCGAACTGTTCTGCCGCGAAGCGCAGGCACCGGT
TATCGCGATCACTGGCTCCAACGGCAAAAGCACCGTCACCACGCTGGTGGGTGAAATGGCGAAAGCCGCGGGCATTAACG
TGGGCGTCGGCGGCAATATCGGTTTACCTGCTCTGATGCTGCTGGATCAGGATCGTGAATTGTACGTTCTGGAACTCTCA
AGCTTCCAGCTCGAGACCACGTCGAGTTTGCACGCCGTTGCTGCGACGATCCTGAACGTTACCGAAGATCATATGGACCG
TTATCCGTTTGGGTTGCAGCAATATCGTGCGGCCAAACTGCGCGTCTATGAAAATGCCAAAGTGTGCGTAGTGAATGCCG
ACGATGCGCTGACCATGCCGGTGCGCGGTGCGGATGAACGCTGCGTCAGTTTTGGCATCAATATGGGTGACTATCACCTG
AATCATCAGCAGGGCGAAACCTGGCTGCGTGTGAAAGGTGAGAAAGTGTTGAACGTGAAAGAGATGAAACTTTCCGGACA
GCATAACTACACCAATGCGCTGGCAGCACTGGCGCTGGCAGATGCTGCGGGTCTACCGCGTGCATCAAGTCTGAAAGCAT
TGACCACGTTTACGGGCCTGGCGCATCGCTTCCAACTGGCGCTTGAGCATAACGGCGTTCGCTGGATCAACGACTCAAAA
GCCACCAACGTCGGCAGCACAGAAGCCGCGCTAAATGGGTTACGTGTCGATGGTACGTTATACCTGCTGCTCGGCGGCGA
CGGTAAATCAGCGGATTTCTCATCTCTCAAGCCTTATCTGACAGGCGATAAAATCCGCTTGTACTGCTTTGGCCGTGACG
GTGCTGAACTGGCCGCGTTGCGCCCGGAAATCGCGACACAGACTGAGACCATGGAACAGGCGATTCGCCTTATTGCACCG
GCAGTTCAGCCGGGTGATATGGTGCTGCTGTCTCCAGCCTGTGCGAGCCTCGATCAGTTTAAGAATTTCGAACAGCGTGG
CGATCTCTTTGCCCGCCTGGCGAAGGAGTTAGGCTGA

Protein sequence :
MADYQGKKVVIIGLGLTGLSCVDFFLGRGVTPRVMDTRVSPPGLDKLPEEVERHLGGLNDDWLLAADLIVASPGFALAHP
SLSAAADAGVEIVGDIELFCREAQAPVIAITGSNGKSTVTTLVGEMAKAAGINVGVGGNIGLPALMLLDQDRELYVLELS
SFQLETTSSLHAVAATILNVTEDHMDRYPFGLQQYRAAKLRVYENAKVCVVNADDALTMPVRGADERCVSFGINMGDYHL
NHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSK
ATNVGSTEAALNGLRVDGTLYLLLGGDGKSADFSSLKPYLTGDKIRLYCFGRDGAELAALRPEIATQTETMEQAIRLIAP
AVQPGDMVLLSPACASLDQFKNFEQRGDLFARLAKELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-54 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-54 43