Gene Information

Name : hemC (Ent638_3987)
Accession : YP_001178693.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4321292 - 4322233 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAATGTTTTGAGAATTGCCACACGCCAAAGCCCACTCGCGCTTTGGCAGGCACAATATGTGAAGCAGCGCCT
CGAAGCCTGCCATCAAGGGTTGCGTGTTGAACTGGTTCCGATGGTGACGCGCGGCGATGTGATTCTGGATACGCCCCTGG
CAAAAGTGGGTGGAAAAGGCTTGTTTGTCAAAGAGCTGGAAATCGCACTGCTTGAGAACCGCGCCGATATCGCCGTCCAT
TCAATGAAGGATGTGCCAGTCGAATTCCCAGAAGGATTAGGGCTGGTGACAATTTGCGAGCGCGAAGATCCCCGCGATGC
TTTCGTCTCAAACCGCTACGCTTCTTTGGATGATTTGCCCAAAGGAAGCGTGGTTGGCACGTCAAGTTTACGCCGTCAGT
GTCAACTGGCTGAACGCCGCCCAGACTTGGTCATCCGCTCTCTGCGCGGAAACGTCGGCACGCGCCTCGGCAAGCTCGAT
AATGGTGATTATGATGCCATTATTCTGGCGGTCGCTGGCCTTAAGCGCCTTGGGCTGGAATCACGAATTCGCGTCGCGAT
GCCACCAGAACTGTGCCTGCCCGCCGTCGGTCAGGGTGCCGTGGGGATTGAATGTCGTCTCGATGACGACCGCACCCGCG
CGCTGCTCTCGCCGCTAAATCATGATGAAACCGCTATTCGCGTCCAGGCTGAGCGGGCAATGAACATGCGACTTGAAGGC
GGCTGTCAGGTTCCGATTGGCAGCTATGCTGAATTGATTAACGGTGAGCTTTGGCTGCGCGCATTAGTGGGCGCACCAGA
CGGTTCACAGATGGTGCGTGGTGAACGCCGCGGCTTGCCGCAAGATGCCGAAATGCTGGGCATATCACTGGCCGATGAGC
TGCTGAACAATGGCGCGCGCGCGATCCTGGCAGACGTTTATAACGGAGAACCACCAGCATGA

Protein sequence :
MLDNVLRIATRQSPLALWQAQYVKQRLEACHQGLRVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLENRADIAVH
SMKDVPVEFPEGLGLVTICEREDPRDAFVSNRYASLDDLPKGSVVGTSSLRRQCQLAERRPDLVIRSLRGNVGTRLGKLD
NGDYDAIILAVAGLKRLGLESRIRVAMPPELCLPAVGQGAVGIECRLDDDRTRALLSPLNHDETAIRVQAERAMNMRLEG
GCQVPIGSYAELINGELWLRALVGAPDGSQMVRGERRGLPQDAEMLGISLADELLNNGARAILADVYNGEPPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-83 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-83 61