Gene Information

Name : thyA (Ent638_3269)
Accession : YP_001177984.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3569360 - 3570154 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTTGAATTGATGAAAAAAGTGCTTGATGAGGGCACGCCGAAAAACGACCGCACCGGAACGGGTACGCT
CTCTATTTTTGGCCACCAGATGCGTTTCAATCTGCAAGAAGGCTTCCCACTGGTGACAACGAAGCGCTGCCATTTGCGCT
CGATCATTCATGAGCTACTCTGGTTCCTGCAAGGCGATACTAACGTTGCTTATCTGCGTGAAAACAACGTATCTATCTGG
GACGAATGGGCGGATGAAAATGGCAACCTGGGGCCGGTTTATGGTCACCAGTGGCGCGCTTGGCCTACGCCTGATGGCCG
TCATATTGATCAGATCACCACCGTGCTCAATCAGCTAAAAAACGATCCAGACTCGCGACGCATTATTGTGTCCGCCTGGA
ACGTCGGTGAGCTGGACAAAATGGCGCTAGCGCCTTGTCATGCTTTCTTCCAGTTCTACGTTGCCGATGGCAAGCTCTCT
TGTCAGCTTTACCAACGCTCTTGCGATGTCTTCCTTGGTTTGCCATTCAACATTGCCAGCTACGCGTTGCTGGTGCATAT
GATGGCGCAGCAATGCGACCTGGAAGTGGGTGATTTTGTCTGGACAGGTGGCGATACCCATCTCTACAGCAATCACATGG
AACAGACGCACCTTCAGTTGACTCGTGAACCGCGGGCTTTGCCGAAGCTGGTCATCAAGCGTAAGCCGGAGTCTATCTTC
GACTATCGCTTCGAAGATTTTGAAATTGAAGGCTACGATCCGCACCCTGGCATTAAAGCGCCCGTGGCTATCTAA

Protein sequence :
MKQYLELMKKVLDEGTPKNDRTGTGTLSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNVAYLRENNVSIW
DEWADENGNLGPVYGHQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMEQTHLQLTREPRALPKLVIKRKPESIF
DYRFEDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-88 66