Gene Information

Name : smpB (Ent638_3100)
Accession : YP_001177815.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3374155 - 3374661 bp
Length : 507 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACCTATGGTTTTACGACACTTATGACGAAGAAAAAAGTACATAAACCTGGCTCGGCCACCATTGCGCTCAACAAGCG
TGCCCGCCATGAATATTTCATTGAAGAAGAATTCGAAGCTGGTCTCTCCTTACAGGGCTGGGAAGTTAAATCCCTGCGTG
CGGGGAAAGCCAATATCAGCGACAGCTATGTGATCCTGATTGATGGCGAAGCCTTCCTGTTCGGCGCGAACTTCACGCCG
CTGGCTGTCGCCTCTTCCCACTACGTTTGCGATCCGATTCGCACCCGTAAACTGCTGCTGAATCAGCGCGAGCTGGAATC
CCTTTTCGGGCGTATCAACCGTGAAGGTTACACCGTCGTTGCGCTCTCGCTGTACTGGAAGAACGCCTGGTGCAAAGTCA
AAATTGGCGTTGCGAAAGGTAAGAAACAGCATGACAAACGTTCAGATCTGAAAGATCGCGAATGGCAGGTCGATAAAGCA
CGAATCATGAAACATGCAGGGCGTTAA

Protein sequence :
MTYGFTTLMTKKKVHKPGSATIALNKRARHEYFIEEEFEAGLSLQGWEVKSLRAGKANISDSYVILIDGEAFLFGANFTP
LAVASSHYVCDPIRTRKLLLNQRELESLFGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKDREWQVDKA
RIMKHAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-50 69
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-26 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-18 41