Gene Information

Name : alr (Ent638_0257)
Accession : YP_001174997.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 302166 - 303245 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACTGTAGTCATTAACCGCCGCGCTCTGCGACACAACCTGCAACGTCTGCGTGAACTGGCGCCCGCCAG
TAAACTCGTTGCAGTCGTGAAAGCGAACGCTTACGGACACGGTCTTCTTGAGACCGCGCGAACGCTCCCTGATGCCGATG
CCTTTGGCGTCGCCCGTCTCGAAGAAGCCCTACGTTTACGCGCGGGCGGTATTACGCAACCCATTCTGTTGTTAGAAGGT
TTCTTTGAAGCGACTGACCTGACGACGATCGCCGATCAGCATCTGCACACAGCGATTCACAATGAAGAACAGCTGCTGGC
GTTGGAAACGGCTGAACTGAGCGAACCGGTCACCGTGTGGATGAAGCTTGATACTGGCATGCATCGCCTGGGCGTGCGTC
CGGAACAGGCCGAGGCGTTTTATCAGCGCTTAAGCCAGTGCAAAAACGTGCACCAGCCGGTGAATATCGTCAGCCATTTT
GCCCGCGCCGACGAACCGGAATGTGGCGCAACGGAGCAGCAGCTCGATATTTTTAATACCTTTTGCGAAGGCAAGCCAGG
CATGCGTTCTATCGCCGCTTCTGGCGGCATTTTGCTGTGGCCGCAATCGCACTTTGACTGGGCGCGGCCTGGCATCATTC
TTTACGGCGTTTCACCGCTGGAAAACAAACCCTGGGGCCCTGATTTTGGTCTGCAGCCGGTAATGTCTTTGGTGTCGAAC
CTGATCGCTGTGCGCGAGCACAAAGCGGGTGAACCTGTTGGCTATGGCGGCACGTGGGTGAGCGAGAGCGATACGCGCCT
GGGCGTTGTGGCGATGGGTTATGGCGACGGTTATCCACGCGCGGCACCTTCGGGAACGCCAGTGCTGGTGAATGGCCGTG
AGGTGAAGATTGTCGGCCGTGTCGCGATGGACATGATTTGCGTCGATCTGGGGCCAGACGCTCAGGATAAAGCGGGTGAT
GCCGTTGTGCTGTGGGGCGAAGGTTTGCCTGTTGAGCGGATTGCTGAAATCACGAAAGTGAGTGCTTACGAACTTATCAC
GCGTCTGACGTCTCGCGTGGCGATGAAATACATCGACTAA

Protein sequence :
MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITQPILLLEG
FFEATDLTTIADQHLHTAIHNEEQLLALETAELSEPVTVWMKLDTGMHRLGVRPEQAEAFYQRLSQCKNVHQPVNIVSHF
ARADEPECGATEQQLDIFNTFCEGKPGMRSIAASGGILLWPQSHFDWARPGIILYGVSPLENKPWGPDFGLQPVMSLVSN
LIAVREHKAGEPVGYGGTWVSESDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVKIVGRVAMDMICVDLGPDAQDKAGD
AVVLWGEGLPVERIAEITKVSAYELITRLTSRVAMKYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-55 42