Gene Information

Name : Ent638_2568 (Ent638_2568)
Accession : YP_001177288.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2768692 - 2771754 bp
Length : 3063 bp
Strand : +
Note : PFAM: acriflavin resistance protein; KEGG: yps:YPTB0566 heavy metal/multi-drug efflux protein, RND family

DNA sequence :
ATGGATATCTCCCGCCAGTTTATCGACAATCCCATTCGCGTCTGGCTGACTATTCTGCTGCTGGGCGTCGGCGGTGTTTT
TGCGCTGCTGAACATCGGTCGTCTTGAAGATCCTGCGTTCACCATTAAAACTGCGGTGGTCATTACTCACTATCCGGGTG
CCTCCGCACAGCAGGTCGAAGAAGAGGTCACCCTGCCCCTGGAAAACGCGTTACAGCAGCTACCCTCGCTCGATAACGTG
AGTTCGATTTCATCAAATGGGTTATCGCAAATCACCGTCAATATTGCCTCGCGTTATCATTCCAGCGAGCTGCCGCAAAT
CTGGGATGAGCTGCGTCGTCGCGTTGGTGACGCTTCGCGCCAGTTCCCTCCGGGCGTCGTGACGCCGTTTGTGAATGATG
ATTTTGGCGATGTGTTTGGTTTCTTTTTTGCCCTTTCCGGCGATGAATTTACCAACGCTGAACTGGCGCGTTACGCCGAT
CAGCTGCGCCGCGAACTGGTCTTGATCCCCGGCGTCGGCAAAGTCGCCATTGGTGGCGCAATACCGCAGCAGATCAATGT
CGATATTTCGCTACCCAAAATGGCCGCGCGCGGGATTACGCTTGCGCAGCTTTCCGCGATCCTAAGCCGCGTAAATGTGG
TGTCTAACGCCGGTGAGATTGCCTCCGGCACCGAGTCGATTCGCCTGCATCCGACCGGCGAATTTGAAAATATCGATGAG
CTGGGTGATTTGATCATCACCCCATACGGCGCGGGGGCTGCGACGCGTCTGCGTGATATCGCCACGCTGTCACGCGGGCT
GACGGAATCGCCTTCCAGTATCTACCACGCCAACGGTCAGCAGGCCGTCACCATGGGCGTGTCGTTCATTCCCGGCGTCA
ATGTGATTGATGTGGGGCGTGCGTTAGAGGCCAAACTGCAGCAAATGTCGGCGGAAAAACCGGCGGGCATTAACATCGAT
CTGTTTTACGATCAGGCTGCGGAAGTCGGGCATTCGGTCAACGGATTTATCATCAACTTCCTGATGGCACTGGCGATTGT
TATCGGCGTTCTGCTGATTTTTATGGGCATTCGCAGCGGGATTATTATCGCGCTTTCCCTCGCGCTTAACGTGCTAGGCA
CGTTGCTCATTATGTACCTCTGGGGAATCGAGCTGCAGCGCATTTCCCTCGGGGCGCTGATCATCGCCCTGAGTATGCTG
GTCGATAACGCGATTGTGATTGTCGAAGGGGTGCTAATTGCCCGACAGCAGGGTTCAACCCTGATGACCGCCGTGAATTA
CGTGATTCGCCGCTCGGCGCTGCCGCTGCTGGGCGCCACGGTGATCGCTATACTGGCTTTTGCGCCCATCGGACTGTCTC
AGGATTCGACCGGCGAATACTGCAAATCGCTGTTCCAGGTTTTGCTGATTTCGCTGATGTTGAGCTGGTTCTCGGCGCTC
ACGATTACGCCGGTGATGATCAAATGGTGGCTGTTCAAAGGGCAAAAAACAGCGGAAACGCCTGCTGAAGCCGATCCTTA
CAACGCGCGGTTTTACCGAATTTATCAGCACATGCTGAATACCCTTCTGGCGCGAAAAACGGTGACGCTAACGTTAATGG
TTGCCTTGCTGGTCGCGGCTGTCTGGGGTTTTGGCTCGGTGCGGCAAAACTTTTTCCCCTCATCGAACACGCCTATTTTC
TTCGTCGATCTGTGGTTGCCTTACGGAACGGATATCAGCCAGACCGAGAAAATGACCGGCGACATCGAAAAAGCGATTAA
CGGCCAGGATGGCGTGGTGACCACGGTGTCGACCATCGGCCAGGGGAGCATGCGCTTTATTCTGACCTACAGCGGCCAAC
GCCAGTACAGCAACTACGCGCAAATTATGGTGCGCATGGACGACCAACGTAATATTCCTGCGCTTGCCCGCCACGTCGAT
GATTACATTGCTCGCCACTATCCGCAGGTTAACGCCAGCACCAAGCGCGTGATGTTCGGTCCGTCTGGCGATAGCGCTAT
TGAGGTGCGCATTAAAGGGCCTGATCCAGACAGACTGCGCCTGATCGCCAGTCAGGTTGACGATATTCTGAGTCGCGATC
CGGCCACCGACAGCGTGCGAAACGACTGGCAGAACCGCAGCAAAGTGATTCGTCCGCAGTATTCACCCGCATTGGGTCGG
GAACTGGGCGTCGATAAGCAAGATATTGATAATGCGCTTGAGATGAATTTCTCCGGGAGTCGGGTGGGCTTATACCGCGA
AGGTTCGGATCTGCTGCCCGTCGTCGTCCGTCCGCCAGAAAATGAACGCCAGGATGCCAACCATCTGAATAACGTGCTGG
TGTGGAGTCAAAACCGTCAGCAGTACATTCCGATGAGCAACGTGGTGAGCGACTTTACGCTCGAGTGGGAAGACCCGCTT
ATTCTGCGCCGGGACCGCAGCCGGGTGCTGACGGTTCAGACCGACCCGTCGCCGCTCAGCCAGCAAACCTCGGGCGATAT
TCTGGCGCGGGTTAAACCTCAGATTGATGCTCTGGCGCTGCCGCACGGCTACAGCATCGAATGGGGCGGCGACGCAGAAA
GTTCTAGCGAGGCACAGCAAGGAGTCTTCTCAACGCTGCCGATTGGGTATCTGGTGATGTTTATTATCACCATCCTGATG
TTCAGCTCGGTGAAAAACGCCGTCGCCATCTGGCTGACGGTGCCGCTGGCGCTGATCGGCGTCACGCCAGGCTTTTTGCT
GACCGGCATTCCGTTCGGTTTTATGGCGCTGATCGGGTTACTGAGCCTCAGTGGAATGCTTATCCGTAACGGCATTGTAT
TGGTCGAAGAAATTGAGCAGCAGAAGCAGCAAAAGCCGCAGCACGAGGCGATTGTCTATGCCGCGACGTCTCGTTTGCGC
CCTATTCTGTTGACCGCATTTACCACCGTGTTGGGGCTGGCTCCGCTCCTGCGTGATGTGTTCTTCCAGAGCATGGCGGT
GGTGATTATGTTCGGGCTAGGTTTTGCGACCATCTTGACGCTTCTGGTACTTCCGGTTATTTATGCCTGTTTCCATCGAC
CGCGAGAGAAAGAAGTACCATGA

Protein sequence :
MDISRQFIDNPIRVWLTILLLGVGGVFALLNIGRLEDPAFTIKTAVVITHYPGASAQQVEEEVTLPLENALQQLPSLDNV
SSISSNGLSQITVNIASRYHSSELPQIWDELRRRVGDASRQFPPGVVTPFVNDDFGDVFGFFFALSGDEFTNAELARYAD
QLRRELVLIPGVGKVAIGGAIPQQINVDISLPKMAARGITLAQLSAILSRVNVVSNAGEIASGTESIRLHPTGEFENIDE
LGDLIITPYGAGAATRLRDIATLSRGLTESPSSIYHANGQQAVTMGVSFIPGVNVIDVGRALEAKLQQMSAEKPAGINID
LFYDQAAEVGHSVNGFIINFLMALAIVIGVLLIFMGIRSGIIIALSLALNVLGTLLIMYLWGIELQRISLGALIIALSML
VDNAIVIVEGVLIARQQGSTLMTAVNYVIRRSALPLLGATVIAILAFAPIGLSQDSTGEYCKSLFQVLLISLMLSWFSAL
TITPVMIKWWLFKGQKTAETPAEADPYNARFYRIYQHMLNTLLARKTVTLTLMVALLVAAVWGFGSVRQNFFPSSNTPIF
FVDLWLPYGTDISQTEKMTGDIEKAINGQDGVVTTVSTIGQGSMRFILTYSGQRQYSNYAQIMVRMDDQRNIPALARHVD
DYIARHYPQVNASTKRVMFGPSGDSAIEVRIKGPDPDRLRLIASQVDDILSRDPATDSVRNDWQNRSKVIRPQYSPALGR
ELGVDKQDIDNALEMNFSGSRVGLYREGSDLLPVVVRPPENERQDANHLNNVLVWSQNRQQYIPMSNVVSDFTLEWEDPL
ILRRDRSRVLTVQTDPSPLSQQTSGDILARVKPQIDALALPHGYSIEWGGDAESSSEAQQGVFSTLPIGYLVMFIITILM
FSSVKNAVAIWLTVPLALIGVTPGFLLTGIPFGFMALIGLLSLSGMLIRNGIVLVEEIEQQKQQKPQHEAIVYAATSRLR
PILLTAFTTVLGLAPLLRDVFFQSMAVVIMFGLGFATILTLLVLPVIYACFHRPREKEVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 3e-166 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ent638_2568 YP_001177288.1 acriflavin resistance protein BAC0519 Protein 0.0 50
Ent638_2568 YP_001177288.1 acriflavin resistance protein BAC0428 Protein 0.0 49
Ent638_2568 YP_001177288.1 acriflavin resistance protein BAC0526 Protein 0.0 48
Ent638_2568 YP_001177288.1 acriflavin resistance protein BAC0425 Protein 1e-166 41