Gene Information

Name : sirA; uvrY (Ent638_2501)
Accession : YP_001177221.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 2699598 - 2700254 bp
Length : 657 bp
Strand : -
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATCAACGTCCTTCTTGTTGATGACCACGAACTCGTGCGCGCAGGGATACGTCGCATACTTGAAGATATAAAGGGTAT
TAAAGTGGCCGGAGAAGCCTGCTGCGGTGAAGACGCCGTGAAGTGGTGCCGAAGCAACTCTGCCGATGTGGTGCTTATGG
ACATGAATATGCCTGGCATCGGTGGGCTTGAAGCCACGCGCAAAATCGCCCGCGCCTTCGTTGATACCAAAGTCATCATG
CTGACCGTGCATACTGAAAACCCCTTGCCCGCGAAAGTGATGCAGGCTGGCGCAGCCGGTTATCTCACTAAAGGCGCTGC
GCCGCAGGAAGTGGTGAATGCCATTCGCTCCGTGTATGCCGGACAGCGCTATATCGCTTCGGATATCGCTCAACAGATGG
CGTTGAGCCAGATTGAGCCGGAAAAGACGGGTTCACCGTTTGCCAGTTTGTCTGAGCGCGAATTGCAGATTATGCTGATG
ATCACCAAAGGCCAAAAGGTGAATGAGATTTCGGAGCAACTGAATCTTAGCCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTGAACATTCATGGCGATGTCGAACTCACTCACCTGGCTATTCGTCATGGTCTGTGTAATACAGAGA
CCCTAACCAGCCAGTGA

Protein sequence : 
MINVLLVDDHELVRAGIRRILEDIKGIKVAGEACCGEDAVKWCRSNSADVVLMDMNMPGIGGLEATRKIARAFVDTKVIM
LTVHTENPLPAKVMQAGAAGYLTKGAAPQEVVNAIRSVYAGQRYIASDIAQQMALSQIEPEKTGSPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNTETLTSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 1e-45 51
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 1e-45 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA; uvrY YP_001177221.1 response regulator VFG1889 Protein 1e-52 52