Gene Information

Name : cvrA; nhaP2; ycgO (Ent638_2361)
Accession : YP_001177081.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 2550341 - 2552074 bp
Length : 1734 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCGCAGCGATAATCAGTCTTTTCATTTTGGGTTCAGTCCTCGTAACCTGCAGTATTTTATTAAGTTCATTTTC
GTCGCGTCTCGGCATACCTATACTAGTTATCTTCCTCGCCATCGGCATGCTTGCTGGCATCGATGGTATTGGCGGTATTC
CCTTCGATAACTATCCCTTCGCCTACATGGTGAGTAACCTCGCGCTGGCGGTGATATTGCTGGATGGCGGGATGCGTACG
CAGGCCAGCTCCTTTCGCGTGGCACTCGGTCCAGCGCTGTCGCTGGCGACGGTCGGTGTCCTGATCACTTCCGGTCTGAC
CGGCATGATGGCCGCCTGGCTGTTCCACCTGGATATCATGGAAGGGCTGCTGATCGGCGCGATCGTCGGGTCTACCGATG
CCGCCGCGGTGTTTTCCCTGCTCGGCGGTAAAGGGCTGAACGAACGTGTTGGCTCAACGCTGGAGATTGAATCCGGCAGC
AACGATCCGATGGCGGTGTTTCTGACCATCACGCTGATTGAGATGATTCAGCAGCATGAAACCGGCCTGAGCTGGATGTT
CGCCTGGCATATTCTGCAGCAGTTTGGACTGGGGATTATCATCGGCTTAGCGGGTGGCTACCTGCTGCAACAGATGATCA
ACCGTATTTCCCTGCCTGCTGGCCTGTATCCTCTGCTCGCACTGAGCGGCGGTATTCTGATTTTCGCCCTGACGACCGCA
CTAGACGGCAGCGGCATTCTGGCTGTTTATCTCTGCGGTTTTCTGCTGGGTAATCGCCCGATACGCAACCGCCACGCGAT
TTTGCAAAACTTTGACGGCCTGGCGTGGCTGGCGCAAATCGGCATGTTCCTGGTGCTCGGCCTGCTGGTGACGCCGTCCG
ATCTGCTGCCGATTGCCATTCCGGCGCTGCTGCTTTCGGCGTGGATGATTTTCTTTGCCCGTCCGCTGTCAGTCTTTGCC
GGACTGCTGCCGTTTCGCGGGTTTAATCTGCGCGAACGCATCTTCATCAGTTGGGTCGGTCTGCGCGGCGCGGTGCCGAT
CATTCTTGCCGTTTTCCCGATGATGGCAGGTCTGGATAACGCGCGGCTGTTCTTCAACGTCGCATTTTTTGTGGTTTTGG
TGTCGCTGCTATTCCAGGGGACGTCTCTGGGATGGGCGGCAAAAAAAGCGAAAGTGGTGGTTCCACCTGTCGGTTTACCG
GTTTCACGCGTAGGGCTCGATATTCATCCGGAAAATCCGTGGGAGCAGTTTGTTTATCAGCTGAGTGCTGATAAATGGTG
CGTTGGCGCATCGCTTCGCGATCTGCATATGCCCACCGAAACGCGTATTGCCGCGCTGTTTCGTGATAATGCCCTACTGC
ACCCGACTGGCAGTACCCGCCTGCGCGAGGGGGATATTCTCTGCGTAATCGGCCGTGAAACCGACCTTCCGGCGCTCGGC
AAGCTGTTCAGCCAGTCGCCACCGGTGGCGCTGGATCAGCGTTTCTTCGGTGATTTTATACTGGAAGCCAGCGCGAAATT
TGCCGATGTGGCTCTGATTTACGGGCTGGATGAGGGTCTGGAGTACCGCGATAAACAGCAGACGCTGGGCGAGATCGTGC
AGCAACTTCTGGGCGCTGCACCCGTCGTCGGCGATCAGGTTGAATTTGCCGGGATGATCTGGACCGTCGCGGAGAAAGAA
GATAACGCGGTGCGCAAAGTGGGCGTGCGCCCTACAGAGGATGAGCCTGAGTAA

Protein sequence :
MDAAAIISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALGPALSLATVGVLITSGLTGMMAAWLFHLDIMEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHETGLSWMFAWHILQQFGLGIIIGLAGGYLLQQMINRISLPAGLYPLLALSGGILIFALTTA
LDGSGILAVYLCGFLLGNRPIRNRHAILQNFDGLAWLAQIGMFLVLGLLVTPSDLLPIAIPALLLSAWMIFFARPLSVFA
GLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLFQGTSLGWAAKKAKVVVPPVGLP
VSRVGLDIHPENPWEQFVYQLSADKWCVGASLRDLHMPTETRIAALFRDNALLHPTGSTRLREGDILCVIGRETDLPALG
KLFSQSPPVALDQRFFGDFILEASAKFADVALIYGLDEGLEYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNAVRKVGVRPTEDEPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 92
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 92